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MEDICAL INFORMATION
Itraconazole Key Facts
What dosages is Itraconazole available in?
Itraconazole is available as a 100 mg oral capsule and a 10 mg/ml oral solution.
What is Itraconazole used for?
Itraconazole is an antifungal and is used to treat oral fungal infections (thrush) of the mouth and throat.
How does Itraconazole work?
Itraconazole is an antifungal solution. It kills the fungus causing the infection by damaging its protective outer layer.
How do I take Itraconazole?
Itraconazole is dosed as follows:
- Oral thrush of the mouth: The typical dose is 200 mg by mouth without food once a day for 1 to 2 weeks
- Oral thrush of the mouth when fluconazole has already been tried: The typical dose is 100 mg by mouth without food twice a day for 2 to 4 weeks
- Oral thrush of the esophagus: The typical dose is 100 mg without food once a day for at least 3 weeks and until you’ve been symptom-free for 2 weeks in a row. Some people might need to take 200 mg per day if the lower dose isn’t working
Is it safe for me to take Itraconazole?
Itraconazole is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if any of the following apply:
- Congestive heart failure
- Taking medications that can lead to QT prolongation (e.g. dofetilide (Tikosyn), quinidine, pimozide (Orap), cisapride, methadone (Methadose), disopyramide (Norpace), Multaq (dronedarone), and ranolazine (Ranexa))
- Taking dihydroergotamine or ergotamine.
People with kidney or liver problems taking colchicine (Colcrys), fesoterodine (Toviaz), or solifenacin (Vesicare)
Itraconazole Common Side Effects
Common side effects of Itraconazole:
- Nausea
- Diarrhea
- Vomiting
- Fever
- Rash
Itraconazole Serious Side Effects
Serious side effects are rare with Itraconazole. Contact your healthcare provider immediately if you experience any of the following.
- Congestive heart failure (CHF): trouble breathing, swelling in the arms and legs, sudden weight gain, tiredness, dizziness, lightheadedness, feeling your heart beat very fast
- Abnormal heart rhythm: dizziness, feeling faint, lightheaded, feeling your heart beating fast
- Liver failure: nausea, vomiting, unusual tiredness, yellowing of the skin or whites of the eyes (jaundice), dark-colored urine, pale-colored stools
Effects of other drugs, drug classes and over-the-counter products on Itraconazole
The following medications may interact with Itraconazole:
- Coadministration of a number of CYP3A4 substrates are contraindicated with Itraconazole
- Some examples of drugs for which plasma concentrations increase are: methadone, disopyramide dofetilide, dronedarone, quinidine, isavuconazole, ergot alkaloids (such as dihydroergotamine ergometrine (ergonovine), ergotamine, methylergometrine (methylergonovine)), irinotecan lurasidone, oral midazolam, pimozide, triazolam, felodipine, nisoldipine, ivabradine, ranolazine eplerenone, cisapride, naloxegol, lomitapide, lovastatin, simvastatin, avanafil, ticagrelor finerenone, voclosporin
Who makes Itraconazole?
Various FDA-approved generic manufacturers
Is Itraconazole safe in pregnancy?
Itraconazole can harm your unborn baby. Tell your healthcare
provider right away if you become pregnant while taking Itraconazole. Females who are able to become
pregnant must use effective forms of birth control during treatment and for 2 months after stopping treatment with
Itraconazole.
What is the brand name for Itraconazole?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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