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selexipag

selexipag

Used for Hypertension

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Manufactured by various FDA-approved generic manufacturers.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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    Obtain your selexipag at no cost. Suitable for insured, underinsured and uninsured individuals
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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

selexipag Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is selexipag available in?

What dosages is selexipag available in?

selexipag is available as a 200 mcg, 400 mcg, 600 mcg, 800 mcg, 1000 mcg, 1200 mcg, 1400 mcg, and 1600 mcg oral tablet and a 1800 mcg injection for IV use.

What is selexipag used for?

What is selexipag used for?

selexipag is a prostacyclin agonist and is used to treat pulmonary arterial hypertension or PAH (high blood pressure in the blood vessels in your lungs).

How does selexipag work?

How does selexipag work?

selexipag is a prostacyclin agonist. It acts like prostacyclin, a natural chemical in your body, to relax the blood vessels in your lungs. This lowers the blood pressure in your lungs and allows more blood to flow through. As a result, your heart is able to pump better, your body gets more oxygen, and you should be able to breathe and exercise easier.

How do I take selexipag?

How do I take selexipag?

selexipag is typically started at 200 mcg by mouth twice daily. Your provider will slowly raise your dose to the highest dose you can tolerate. The maximum dose is 1,600 mcg twice daily. Your dose might differ if you have liver problems. It might also differ you’re taking certain medications that can interact with selexipag, such as clopidogrel (Plavix) or rifampin (Rifadin). selexipag is also available as an intravenous (IV) infusion into your veins that’s given by a healthcare provider in the hospital.

Is it safe for me to take selexipag?

Is it safe for me to take selexipag?

selexipag is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:

  • Concomitant use with strong CYP2C8 inhibitors
  • Hypersensitivity to the active substance or to any of the excipients
selexipag Common Side Effects

selexipag Common Side Effects

Common side effects of selexipag:

  • Headache
  • Diarrhea
  • Nausea
  • Jaw pain
  • Vomiting
  • Pain in arms or legs
  • Muscle pain
  • Flushing
selexipag Serious Side Effects

selexipag Serious Side Effects

Serious side effects are rare with selexipag.

Effects of other drugs, drug classes and over-the-counter products on selexipag

Effects of other drugs, drug classes and over-the-counter products on selexipag

The following medications may interact with selexipag:

  • Moderate CYP2C8 inhibitors (e.g., clopidogrel, deferasirox and teriflunomide) increase exposure to the active metabolite of selexipag. Reduce the dosing of selexipag to once daily CYP2C8 inducers (e.g., rifampin) decrease exposure to the active metabolite
  • Increase up to twice the dose of selexipag
Who makes selexipag?

Who makes selexipag?

Various FDA-approved generic manufacturers

Is selexipag safe in pregnancy?

Is selexipag safe in pregnancy?

There are no adequate and well-controlled studies with selexipag in pregnant women. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

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What to do if you missed your selexipag dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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