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Rotigotine is available as a patch that delivers 1 mg/24 hours, 2 mg/24 hours, 3 mg/24 hours, 4 mg/24 hours, 6 mg/24 hours, and 8 mg/24 hours of Rotigotine.

Rotigotine is a dopamine agonist and is used for the following:
Parkinson’s disease Moderate-to-severe restless legs syndrome

Rotigotine is a dopamine agonist that binds to and stimulates dopamine receptors in the brain. This raises the levels of dopamine, which is a chemical that can help lessen movement problems for people with Parkinson’s Disease or restless legs syndrome.

Rotigotine is dosed as follows:

• Early-stage Parkinson’s Disease: The recommended starting dose is 2 mg applied as a patch on the skin once daily. If needed and as instructed by your provider, the dose can be raised by 2 mg on a weekly basis until desired effects are reached. The maximum recommended dose is 6 mg per 24 hours
• Advanced-stage Parkinson’s Disease: The recommended starting dose is 4 mg applied as a patch on the skin once daily. If needed and as instructed by your provider, the dose can be raised by 2 mg on a weekly basis until desired effects are reached. The maximum recommended dose is 8 mg per 24 hours
• Restless legs syndrome: The recommended starting dose is 1 mg applied as a patch on the skin once daily. If needed and as instructed by your provider, the dose can be raised by 1 mg on a weekly basis until desired effects are reached. The maximum recommended dose is 3 mg per 24 hours

Rotigotine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a hypersensitivity to Rotigotine or components of the transdermal patch.

Common side effects of Rotigotine:

• Nausea
• Vomiting
• Sleepiness
• Skin irritation where the patch is applied
• Dizziness
• Headache
• Tiredness
• Uncontrolled, involuntary muscle movements
• Swelling of lower legs or hands
• Trouble sleeping
• Hallucinations
• Joint pain
• Common cold

Serious side effects are rare with Rotigotine. Contact your healthcare provider immediately if you experience any of the following.

• Serious allergic reactions: trouble breathing, swelling of your face, lips, tongue, and throat, hives
• Neuroleptic malignant syndrome (NMS): very high fevers, irregular pulse, sweating, muscle stiffness, confusion, changes in blood pressure

The following medications may interact with Rotigotine:

• Dopamine Antagonists: Dopamine antagonists, such as antipsychotics or metoclopramide, may diminish the effectiveness of Rotigotine

Various FDA-approved generic manufacturers

Rotigotine may cause harm to your unborn baby, based on animal data. Tell your healthcare provider right away if you become pregnant while taking Rotigotine. You and your healthcare provider will have to decide if you should take Rotigotine while you are pregnant.

• Neupro