RoflumilastPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Roflumilast
    Generic for Daliresp
    30 tablets $17.4 USD
    Save $374.70
  3. Roflumilast
    Generic for Daliresp
    141 tablets $77.4 USD
    Save $1765.47
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Do you need a prescription for roflumilast?

Yes, roflumilast is only available with a valid physician Rx.

How much is roflumilast without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase roflumilast, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for roflumilast in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a roflumilast savings card?

Yes. Save up to 90% on your roflumilast with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a roflumilast coupon provider in the US?

No. Now Patient does not provide roflumilast coupons or FREE roflumilast samples.

Do you accept commercial, Medicare or Medicaid coverage for roflumilast in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much roflumilast?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using roflumilast. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much roflumilast. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic roflumilast?

Generic roflumilast refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of roflumilast

Roflumilast is approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic obstructive pulmonary disease (COPD), a progressive lung disease.

Active ingredient of roflumilast

The active ingredient of roflumilast is roflumilast.

US brand name of roflumilast and manufacturer

Roflumilast is available in the US under the brand name Daliresp. The manufacturer is AstraZeneca Pharmaceuticals.

UK brand name of roflumilast and manufacturer

In the UK, roflumilast is available under the brand name Daxas. The manufacturer is AstraZeneca UK Limited.

Prescription requirement for roflumilast

A prescription (Rx) is required for roflumilast in both the US and the UK.

Availability of roflumilast in the UK with NHS prescription

Roflumilast is available in the UK with an NHS prescription.

Conditions treated by roflumilast

Roflumilast is a selective phosphodiesterase-4 inhibitor, primarily used for the maintenance treatment of severe chronic obstructive pulmonary disease (a disease that affects the lungs and airways) associated with chronic bronchitis and a history of exacerbations. It helps reduce the frequency of exacerbations and improve lung function.

How does roflumilast work?

Roflumilast is converted to the active metabolite roflumilast N-oxide by CYP3A4 and CYP1A2. Roflumilast is a PDE4 Inhibitor. It works by inhibiting an enzyme called phosphodiesterase-4. By inhibiting PDE4, it helps reduce inflammation in the lungs, leading to improved lung function and decreased symptoms of severe COPD exacerbation.

Forms of roflumilast available

Roflumilast is available in the form of oral tablets.

Dosage of roflumilast

The dosage of roflumilast is typically one tablet (500 mcg) taken orally once daily. It is important to follow the recommended dosage instructions and medication guide provided by the healthcare provider.

Directions for roflumilast use

Roflumilast should be taken exactly as directed by the healthcare provider. The specific instructions may include the timing of administration, dosage adjustments, and any necessary precautions.

Warnings and contraindications for roflumilast

  • Roflumilast may have certain risks and potential side effects. It is important to discuss these with a healthcare provider before starting the medication
  • Roflumilast is not indicated for the relief of acute bronchospasm or for the treatment of asthma
  • Roflumilast is not recommended for use in patients with moderate to severe hepatic impairment
  • It is not known if roflumilast passes into breast milk. Speak to your doctor before breast-feeding

Use of roflumilast if pregnant or planning pregnancy

The use of roflumilast during pregnancy should be discussed with a healthcare provider. The potential benefits and risks should be evaluated on an individual basis.

Possible side effects of roflumilast

In clinical trials common side effects of roflumilast may include diarrhea, abdominal pain, weight loss, nausea, headache, and back pain. Serious adverse events are rare but can occur. Promptly report any concerning symptoms to a healthcare provider. Get medical help right away if you have a life-threatening allergic reaction. Symptoms include hives, trouble breathing, shortness of breath, chest pain, swelling of the face, tongue or throat (angioedema), skin rash, and severe skin reactions. Promptly report any adverse effects to a caregiver for medical advice.

Interactions with other drugs

Roflumilast may interact with certain medications, including rifamycins (such as rifampicin), strong cytochrome P450 inducers, such as carbamazepine and phenytoin, cimetidine, erythromycin, ketoconazole, and certain oral contraceptives. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medication, supplements, and vitamins you are taking to avoid potential adverse reactions and drug interactions.

Similar drugs to roflumilast

Other medications, such as bronchodilators and inhaled corticosteroids, may be used in combination with or as alternatives to roflumilast for the treatment of COPD.


About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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