roflumilast
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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roflumilast Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is roflumilast available in?
roflumilast is available as a 250 mcg and 500 mcg oral tablet.
What is roflumilast used for?
roflumilast is a PDE-4 inhibitor used for COPD (chronic obstructive pulmonary disease).
How does roflumilast work?
roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. PDE-4 is a protein in your body that is involved in making inflammatory chemicals in the lungs. Because it blocks PDE-4, roflumilast prevents inflammation, which helps you breathe better and prevent COPD flare-ups.
How do I take roflumilast?
roflumilast is typically taken by mouth once daily with or without food. The typical maintenance dose is 500 mcg per day.
Is it safe for me to take roflumilast?
roflumilast is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have moderate to severe liver impairment.
roflumilast Common Side Effects
Common side effects of roflumilast include:
- Diarrhea (10%)
- Weight loss (8%)
- Nausea (5%)
- Headache (4%)
Other Side Effects:
- Back pain
- Flu
- Difficulty sleeping
- Dizziness
- Loss of appetite
- Upset stomach
- Runny nose
- Sinus inflammation
- Urinary tract infection
- Muscle spasm
- Tremor
- Anxiety
- Depression
roflumilast Serious Side Effects
Serious side effects are rare with roflumilast. Contact your healthcare provider immediately if you experience any of the following.
- Depression or suicidal thoughts
Effects of other drugs, drug classes and over-the-counter products on roflumilast
The following medications may interact with roflumilast:
- Inhibitors of CYP3A4 or dual inhibitors of CYP3A4 and CYP1A2 (e.g., erythromycin, ketoconazole, fluvoxamine, enoxacin, cimetidine) – Will increase roflumilast levels and may result in increased adverse reactions
Who makes roflumilast?
Various FDA-approved generic manufacturers
Is roflumilast safe in pregnancy?
It is not known if roflumilast will harm your unborn baby. If you become pregnant while receiving roflumilast, talk to your healthcare provider.
What to do if you missed your roflumilast dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
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Does roflumilast cause anxiety?
What does DALIRESP do to lungs?
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What should I monitor after giving roflumilast?
Is roflumilast effective?
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