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PROMACTA

PROMACTA

Are you tired of high medication costs? Our service offers unbeatable savings on your PROMACTA prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by Novartis Pharmaceuticals

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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PROMACTA cost saving options available to you

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    Buy your PROMACTA without insurance from Canada at discounts of up to 90% using NowPatient's Canadian Prescription savings program.
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    Drug Coupons

    Obtain your PROMACTA for as little as $0 per fill. Suitable for insured individuals only.

    You can pay as little as $0

  • Available

    Patient Assistance Programs

    Obtain your PROMACTA at no cost. Suitable for insured, underinsured and uninsured individuals

    You can receive for FREE

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PROMACTA Uses, Side Effects, Interactions, Warnings & Dosing

What is PROMACTA?

What is PROMACTA?

PROMACTA is the brand name for eltrombopag and is available as an oral tablet and suspension.

What dosages is PROMACTA available in?

What dosages is PROMACTA available in?

PROMACTA is available as a 12.5 mg, 25 mg, 50 mg, and 75 mg oral tablet and a 12.5 mg and 25 mg oral suspension.

What is PROMACTA used for?

What is PROMACTA used for?

PROMACTA is a thrombopoietin receptor agonist and is used for the following:

  • Low platelet count in people with immune thrombocytopenic purpura (ITP) when other medications haven’t worked – adults and children
  • Low platelet count in people with long-term hepatitis C – adults only
  • Used alone or with other medications in people who can’t make enough blood cells (severe aplastic anemia) – adults and children
How does PROMACTA work?

How does PROMACTA work?

PROMACTA is a thrombopoietin receptor (TPO) agonist, meaning it acts like TPO. TPO is a natural hormone that tells your bone marrow to make more blood cells. By working like TPO, PROMACTA raises the level of platelets, red blood cells, and white blood cells in your body. This is important because having a healthy level of these components helps to lower your risk for bleeding, fight against infections, and makes sure enough oxygen is carried throughout your body.

How do I take PROMACTA?

How do I take PROMACTA?

PROMACTA is dosed as follows:

Low platelet count in people with long-term ITP:

  • Adults and children ages 6 and older: The typical starting dose is 50 mg by mouth once daily
  • Children ages 1 to 5 years old: The typical starting dose is 25 mg by mouth once daily
  • Your healthcare provider will adjust your dose based on your platelet levels. The maximum dose is 75 mg a day. Your dose might be lowered if you’re of East Asian or Southeast Asian descent, or if you have liver problems

Low platelet count in people with long-term hepatitis C:

  • The typical starting dose is 25 mg by mouth once daily. Your healthcare provider will adjust your dose based on your platelet levels. The maximum dose is 100 mg a day

Severe aplastic anemia as a first-choice treatment:

  • Adults and children ages 12 and older: The typical starting dose is 150 mg by mouth once daily for 6 months
  • Children ages 6 to 11 years old: The typical starting dose is 75 mg by mouth once daily for 6 months
  • Children ages 2 to 5 years old: The starting dose will depend on your child’s weight. The typical starting dose is 2.5 mg/kg by mouth once daily for 6 months
  • Your dose might be lowered if you’re of East Asian or Southeast Asian descent, or if you have liver problems

Severe aplastic anemia that hasn’t responded to treatment (refractory):

  • Adults and children ages 2 and older: The typical starting dose is 50 mg by mouth once daily
  • Your healthcare provider will adjust your dose based on your platelet levels. The maximum dose is 150 mg a day.
  • Your dose might be lowered if you’re of East Asian or Southeast Asian descent, or if you have liver problems
Is it safe for me to take PROMACTA?

Is it safe for me to take PROMACTA?

PROMACTA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

PROMACTA Common Side Effects

PROMACTA Common Side Effects

Common side effects of PROMACTA:

  • Low red blood cell levels
  • Fever
  • Tiredness
  • Headache
  • Nausea
  • Diarrhea
  • Cough
PROMACTA Serious Side Effects

PROMACTA Serious Side Effects

Serious side effects are rare with PROMACTA. Contact your healthcare provider immediately if you experience any of the following.

  • Liver damage: stomach swelling, dark stool or urine, tiredness, confusion, and yellowing of the skin or eyes
  • Blood clot in the liver: nausea, vomiting, abdominal pain, and diarrhea
  • Other types of blood clots: legs, (redness, pain, tenderness, swelling of the skin), lungs (cough, difficulty breathing, chest pain), heart attack (chest pain, pain in the arms or shoulders, pain in the neck or jaw), stroke (difficulty speaking, numbness on one side of the body, confusion)
Effects of other drugs, drug classes and over-the-counter products on PROMACTA

Effects of other drugs, drug classes and over-the-counter products on PROMACTA

The following medications may interact with PROMACTA:

  • Polyvalent Cations (Chelation): Take PROMACTA at least 2 hours before or 4 hours after any medications or products such as antacids, dairy products, and mineral supplements to avoid significant reduction in absorption of PROMACTA
  • Transporters: Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g. atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin,sulfasalazine, topotecan). Monitor patients closely for signs and symptoms of excessive exposure to the drugs that are substrates of OATP1B1 or BCRP and consider reduction of the dose of these drugs, if appropriate. In  clinical trials with PROMACTA, a dose reduction of rosuvastatin by 50% was recommended
Who makes PROMACTA?

Who makes PROMACTA?

Novartis Pharmaceuticals

Is PROMACTA safe in pregnancy?

Is PROMACTA safe in pregnancy?

It is not known if PROMACTA will harm an unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with PROMACTA.
o Females who are able to become pregnant, should use effective birth control (contraception) during treatment with PROMACTA and for at least 7 days after stopping treatment with PROMACTA. Talk to your healthcare provider about birth control methods that may be right for you during this time.

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What to do if you missed your PROMACTA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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