eltrombopag
NowPatient helps you obtain your eltrombopag prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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eltrombopag key facts
What dosages is eltrombopag available in?
eltrombopag is available as a 12.5 mg, 25 mg, 50 mg, and 75 mg oral tablet and a 12.5 mg and 25 mg oral suspension.
What is eltrombopag used for?
eltrombopag is a thrombopoietin receptor agonist and is used for the following:
- Low platelet count in people with immune thrombocytopenic purpura (ITP) when other medications haven’t worked – adults and children
- Low platelet count in people with long-term hepatitis C – adults only
- Used alone or with other medications in people who can’t make enough blood cells (severe aplastic anemia) – adults and children
How does eltrombopag work?
eltrombopag is a thrombopoietin receptor (TPO) agonist, meaning it acts like TPO. TPO is a natural hormone that tells your bone marrow to make more blood cells. By working like TPO, eltrombopag raises the level of platelets, red blood cells, and white blood cells in your body. This is important because having a healthy level of these components helps to lower your risk for bleeding, fight against infections, and makes sure enough oxygen is carried throughout your body.
How do I take eltrombopag?
eltrombopag is dosed as follows:
Low platelet count in people with long-term ITP:
- Adults and children ages 6 and older: The typical starting dose is 50 mg by mouth once daily
- Children ages 1 to 5 years old: The typical starting dose is 25 mg by mouth once daily
- Your healthcare provider will adjust your dose based on your platelet levels. The maximum dose is 75 mg a day. Your dose might be lowered if you’re of East Asian or Southeast Asian descent, or if you have liver problems
Low platelet count in people with long-term hepatitis C:
- The typical starting dose is 25 mg by mouth once daily. Your healthcare provider will adjust your dose based on your platelet levels. The maximum dose is 100 mg a day
Severe aplastic anemia as a first-choice treatment:
- Adults and children ages 12 and older: The typical starting dose is 150 mg by mouth once daily for 6 months
- Children ages 6 to 11 years old: The typical starting dose is 75 mg by mouth once daily for 6 months
- Children ages 2 to 5 years old: The starting dose will depend on your child’s weight. The typical starting dose is 2.5 mg/kg by mouth once daily for 6 months
- Your dose might be lowered if you’re of East Asian or Southeast Asian descent, or if you have liver problems
Severe aplastic anemia that hasn’t responded to treatment (refractory):
- Adults and children ages 2 and older: The typical starting dose is 50 mg by mouth once daily
- Your healthcare provider will adjust your dose based on your platelet levels. The maximum dose is 150 mg a day.
- Your dose might be lowered if you’re of East Asian or Southeast Asian descent, or if you have liver problems
Is it safe for me to take eltrombopag?
eltrombopag is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
eltrombopag Common Side Effects
Common side effects of eltrombopag:
- Low red blood cell levels
- Fever
- Tiredness
- Headache
- Nausea
- Diarrhea
- Cough
eltrombopag Serious Side Effects
Serious side effects are rare with eltrombopag. Contact your healthcare provider immediately if you experience any of the following.
- Liver damage: stomach swelling, dark stool or urine, tiredness, confusion, and yellowing of the skin or eyes
- Blood clot in the liver: nausea, vomiting, abdominal pain, and diarrhea
- Other types of blood clots: legs, (redness, pain, tenderness, swelling of the skin), lungs (cough, difficulty breathing, chest pain), heart attack (chest pain, pain in the arms or shoulders, pain in the neck or jaw), stroke (difficulty speaking, numbness on one side of the body, confusion)
Effects of other drugs, drug classes and over-the-counter products on eltrombopag
The following medications may interact with eltrombopag:
- Polyvalent Cations (Chelation): Take eltrombopag at least 2 hours before or 4 hours after any medications or products such as antacids, dairy products, and mineral supplements to avoid significant reduction in absorption of eltrombopag
- Transporters: Use caution when concomitantly administering eltrombopag and drugs that are substrates of OATP1B1 (e.g. atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin,sulfasalazine, topotecan). Monitor patients closely for signs and symptoms of excessive exposure to the drugs that are substrates of OATP1B1 or BCRP and consider reduction of the dose of these drugs, if appropriate. In clinical trials with eltrombopag, a dose reduction of rosuvastatin by 50% was recommended
Who makes eltrombopag?
Various FDA-approved generic manufacturers
Is eltrombopag safe in pregnancy?
It is not known if eltrombopag will harm an unborn baby. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with eltrombopag.
o Females who are able to become pregnant, should use effective birth control (contraception) during treatment with eltrombopag and for at least 7 days after stopping treatment with eltrombopag. Talk to your healthcare provider about birth control methods that may be right for you during this time.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my eltrombopag prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your eltrombopag prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient eltrombopag savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient eltrombopag savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for eltrombopag | Canadian Prescription Savings* for eltrombopag | eltrombopag Drug Coupon* | eltrombopag Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of eltrombopag?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for eltrombopag | Canadian Prescription Savings* for eltrombopag | eltrombopag Drug Coupon* | eltrombopag Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the eltrombopag savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the eltrombopag drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for eltrombopag, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the eltrombopag prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, eltrombopag is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed eltrombopag for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the eltrombopag prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the eltrombopag prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for eltrombopag
If you are having trouble paying for your eltrombopag medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for eltrombopag you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- eltrombopag is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers eltrombopag
- If eltrombopag is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for eltrombopag
If you are having trouble paying for your eltrombopag medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for eltrombopag you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers eltrombopag
- If eltrombopag is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for eltrombopag
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your eltrombopag treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for eltrombopag you will need to meet the following criteria:
- You must be currently insured and have coverage for eltrombopag
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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