PACERONE
NowPatient helps you obtain your PACERONE prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Upsher-Smith Laboratories
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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PACERONE key facts
What is PACERONE?
PACERONE is the brand name for amiodarone and is available as an oral tablet.
What dosages is PACERONE available in?
PACERONE is available as a 100 mg, 200 mg, and 400 mg oral tablet.
What is PACERONE used for?
PACERONE is an antiarrhythmic and is used for the:
- Prevention of recurrent (keeps happening) ventricular arrhythmia
- Treatment of ventricular arrhythmia
How does PACERONE work?
PACERONE is an antiarrhythmic. It works by blocking various receptors and channels in your heart, which play a major part in your heart’s electrical activity. PACERONE slows down the electrical activity to help your heartbeat stay in a normal ‘sinus’ rhythm.
How do I take PACERONE?
PACERONE tablets are usually started in the hospital. The typical ‘loading dose’ is 800 mg to 1600 mg per day until the arrhythmia is controlled, which usually takes 1 to 3 weeks. Then the dose goes down to 600 mg to 800 mg per day for one month, then 400 mg per day long-term.
Is it safe for me to take PACERONE?
PACERONE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have:
- Cardiogenic shock
- Sick sinus syndrome, second- or third-degree atrioventricular block, bradycardia leading to syncope without a functioning pacemaker
- Known hypersensitivity to the drug or to any of its components, including iodine
PACERONE Common Side Effects
Common side effects of PACERONE:
- Nausea
- Vomiting
- Constipation
- Poor appetite
- Abdominal pain
- Skin irritation from sun, or sunburn
- Feeling unwell
- Fatigue
- Tremor or abnormal movement
- Poor coordination
- Difficulty walking
- Headache
- Change in vision
- Abnormal liver tests
- Lung inflammation or scarring
- Flushing
- Dizziness
- Pins and needles sensation in the skin
- Lower sex drive
- Difficulty sleeping
PACERONE Serious Side Effects
Serious side effects are rare with PACERONE. Contact your healthcare provider immediately if you experience any of the following.
- New or worsening arrhythmia: Chest discomfort, dizziness, or fainting
- Lung damage: Cough or shortness of breath
- Liver damage: Nausea, vomiting, right-sided stomach pain, fatigue, poor or no appetite, or yellowing of the skin or eyes
- Vision problems
Effects of other drugs, drug classes and over-the-counter products on PACERONE
The following medications may interact with PACERONE:
- QT Prolonging Drugs (class I and III antiarrhythmics, lithium, certain phenothiazines, tricyclic antidepressants, certain fluoroquinolone and macrolide antibiotics, azole antifungals, halogenated inhalation anesthetic agents): Increased risk of Torsade de Pointes. Avoid concomitant use
- Digoxin, beta blockers, verapamil, diltiazem, clonidine, ivabradine: Potentiates the electrophysiologic and hemodynamic effects of amiodarone, resulting in bradycardia, sinus arrest, and AV block. Monitor heart rate
- CYP450 Inhibitors (grapefruit juice, certain fluoroquinolone and macrolide antibiotics, azole antifungals, cimetidine, certain protease inhibitors): Increased exposure of amiodarone. Avoid concomitant use
- CYP450 Inducers (St. John’s Wort): Reduced amiodarone serum levels
- Cyclosporine: Increased plasma levels of cyclosporine have been reported resulting in elevated creatinine, despite reduction of cyclosporine dose. Monitor cyclosporine drug levels and renal function with concomitant use
- Digoxin: Increased digoxin concentration. Reduce digoxin by half or discontinue. If continued, monitor for evidence of toxicity
- HMG-CoA Reductase Inhibitors (simvastatin, lovastatin, atorvastatin): Increased plasma concentration of HMG-CoA reductase inhibitor
- Warfarin: Potentiates anticoagulant response and can result in serious or fatal bleeding. Reduce warfarin dose by one-third to one-half and monitor prothrombin times
- Phenytoin: Increased steady-state levels of phenytoin. Monitor phenytoin levels
Who makes PACERONE?
Upsher-Smith Laboratories
Is PACERONE safe in pregnancy?
Available data from post-marketing reports and published case series indicate that PACERONE use in pregnant women may increase the risk for fetal harm. You should talk to your healthcare provider before taking this medication if you are pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my PACERONE prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your PACERONE prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient PACERONE savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient PACERONE savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for PACERONE | Canadian Prescription Savings* for PACERONE | PACERONE Drug Coupon* | PACERONE Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of PACERONE?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for PACERONE | Canadian Prescription Savings* for PACERONE | PACERONE Drug Coupon* | PACERONE Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the PACERONE savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the PACERONE drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for PACERONE, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the PACERONE prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, PACERONE is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed PACERONE for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the PACERONE prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the PACERONE prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for PACERONE
If you are having trouble paying for your PACERONE medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for PACERONE you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- PACERONE is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers PACERONE
- If PACERONE is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for PACERONE
If you are having trouble paying for your PACERONE medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for PACERONE you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers PACERONE
- If PACERONE is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for PACERONE
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your PACERONE treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for PACERONE you will need to meet the following criteria:
- You must be currently insured and have coverage for PACERONE
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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