omalizumab
Used for Asthma
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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omalizumab Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is omalizumab available in?
omalizumab is available as a 75 mg/0.5 mL, 150 mg/mL, and 300 mg/2 mL single-dose prefilled syringe and autoinjector.
What is omalizumab used for?
omalizumab is an immunoglobulin E (IgE) monoclonal antibody and is used for the following:
- Moderate-to-severe allergic asthma
- Chronic rhinosinusitis with nasal polyps
- Chronic spontaneous urticaria (CSU) (chronic hives of unknown cause)
- Lower risk of severe allergic reactions after accidental exposure to food triggers
How does omalizumab work?
omalizumab is a monoclonal antibody. It targets a specific protein in the immune system called immunoglobulin E (IgE). This protein is typically involved in ramping up your immune system’s allergic response to something, like certain food. omalizumab stops IgE from releasing histamine and other chemicals that cause symptoms of allergic asthma, nasal polyps, hives, and allergic reactions from food.
How do I take omalizumab?
omalizumab is dosed as follows:
- Your allergist will determine and adjust your dose of omalizumab based on different factors like body weight, serum IgE level, and how well the medication is working for you
- omalizumab is given as an injection under the skin (subcutaneous or SC) in either the front and middle of your thigh, stomach area (2 inches away from your belly button), or in the back of the upper arm (if given by a caregiver)
Allergic asthma
- Adults and children ages 6 years and older: The typical dose ranges from 75 mg to 375 mg injected SC every 2 or 4 weeks.
Chronic rhinosinusitis with nasal polyps
- Adults: The typical dose ranges from 75 mg to 600 mg injected SC every 2 or 4 weeks
Chronic idiopathic urticaria (hives)
- Adults and children ages 12 years and older: The typical dose ranges from 150 mg or 300 mg SC every 4 weeks
- Prevention of severe food allergy reactions
- Adults and children ages 1 year and older: The typical dose ranges from 75 mg to 600 mg injected SC every 2 or 4 weeks
Is it safe for me to take omalizumab?
omalizumab is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
omalizumab Common Side Effects
Common side effects of omalizumab:
- Injection site reaction
- Common cold symptoms
- Joint pain
- Body pain
- Leg pain
- Dizziness
- Fatigue
- Headache
omalizumab Serious Side Effects
Serious side effects are rare with omalizumab. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reactions: hives, wheezing, difficulty breathing, swelling of face, mouth, tongue, or throat
- Inflammation of blood vessels: rash, difficulty breathing, tingling or numbness in arms or legs, chest pain
- Heart and blood circulation problems: chest pain, heart attack, blood clots, stroke
- Fever, joint pain, or rash after an injection
- Parasitic infections
Effects of other drugs, drug classes and over-the-counter products on omalizumab
- No formal drug-drug interaction studies with omalizumab have been conducted. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes omalizumab?
Various FDA-approved generic manufacturers
Is omalizumab safe in pregnancy?
It is not known if omalizumab will harm your unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using omalizumab.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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