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Octreotide is available as a 20 mg oral delayed-release capsule.

Octreotide is a somatostatin analog indicated for long-term maintenance treatment in acromegaly patients who have responded to and tolerated treatment with Octreotide or lanreotide.

Octreotide is a somatostatin analog. This means it acts just like the somatostatin hormone your body makes. Somatostatin blocks many other hormones from releasing in your body. This includes growth hormone (GH). Octreotide helps treat acromegaly by blocking your body from releasing too much GH.

The typical starting dose of Octreotide is 20 mg by mouth twice daily on an empty stomach (at least 1 hour before a meal or at least 2 hours after a meal). Your dose may be increased depending on your IGF-1 levels and your symptoms. The maximum dose is 40 mg twice daily.

Octreotide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Hypersensitivity to Octreotide or any of the components of the product

Common side effects of Octreotide:

• Headache
• Nausea
• Joint pain
• Weakness
• Diarrhea
• Sweating a lot
• Swelling in your arms, legs, or feet

Serious side effects are rare with Octreotide. Contact your healthcare provider immediately if you experience any of the following:

• Gallstones and resulting problems: sudden pain in the upper right area of your stomach, swelling in the belly, back pain between your shoulder blades, nausea, vomiting, fever, fast heartbeat, difficulty breathing, yellowing of your skin or eyes
• Dangerously low blood sugar: feeling faint, shaking, sweating, dizziness, fast heartbeat, nervousness, anxious, confused, irritable, feeling very hungry
• Dangerously high blood sugar: feeling thirsty often, needing to urinate often, feeling tired, nausea, vomiting, difficulty breathing, fruity breath, dry mouth
• Heart rate or heart rhythm problems: pounding chest, fluttering in the chest, chest pain, difficulty breathing, feeling faint or lightheadedGallstones and resulting problems: sudden pain in the upper right area of your stomach, swelling in the belly, back pain between your shoulder blades, nausea, vomiting, fever, fast heartbeat, difficulty breathing, yellowing of your skin or eyes
• Dangerously low blood sugar: feeling faint, shaking, sweating, dizziness, fast heartbeat, nervousness, anxious, confused, irritable, feeling very hungry
• Dangerously high blood sugar: feeling thirsty often, needing to urinate often, feeling tired, nausea, vomiting, difficulty breathing, fruity breath, dry mouth
• Heart rate or heart rhythm problems: pounding chest, fluttering in the chest, chest pain, difficulty breathing, feeling faint or lightheaded

The following medications may interact with Octreotide:

• Proton ppump inhibitors, H2-receptor antagonists, or antacids
• Cyclosporine
• Insulin and antidiabetic meds
• Digoxin
• Lisinopril
• Levonorgestrel
• Bromocriptine
• Beta-blockers
• Calcium channel blockers

Various FDA-approved generic manufacturers

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.

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