Liothyronine Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Liothyronine Sodium
    Generic for Cytomel
    30 tablets $9 USD
    Save $27.00
  3. Liothyronine Sodium
    Generic for Cytomel
    30 tablets $8.4 USD
    Save $27.60
  4. Liothyronine Sodium
    Generic for Cytomel
    50 tablets $13.8 USD
    Save $46.20
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Do you need a prescription for liothyronine?

Yes, liothyronine is only available with a valid physician Rx.

How much is liothyronine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase liothyronine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for liothyronine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a liothyronine savings card?

Yes. Save up to 90% on your liothyronine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a liothyronine coupon provider in the US?

No. Now Patient does not provide liothyronine coupons or FREE liothyronine samples.

Do you accept commercial, Medicare or Medicaid coverage for liothyronine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much liothyronine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using liothyronine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much liothyronine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic liothyronine?

Liothyronine is the active form of thyroxine, its name refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of liothyronine

Liothyronine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypothyroidism, a condition characterized by an underactive thyroid gland.

Active ingredient of liothyronine

The active ingredient of liothyronine is liothyronine sodium.

US brand name of liothyronine and manufacturer

Liothyronine is available in the US under various brand names, including Cytomel. The manufacturers may vary depending on the brand names.

UK brand name of liothyronine and manufacturer

In the UK, liothyronine is available under various brand names, including Tertroxin. The manufacturer may vary depending on the brand name.

Prescription requirement for liothyronine

A prescription (Rx) is required for liothyronine in both the US and the UK.

Availability of liothyronine in the UK with NHS prescription

Liothyronine is available in the UK with an NHS prescription.

Conditions treated by liothyronine

Liothyronine is primarily used for the treatment of hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone. It may also be used to treat other thyroid problems, such as goiters, and thyroid cancer. Liothyronine may also be used to test for hyperthyroidism, where the thyroid gland produces too much thyroid hormone.

How does liothyronine work?

Liothyronine is a synthetic form of triiodothyronine (T3), which is a thyroid hormone. Liothyronine is a thyroid hormone replacement therapy, used to suppress TSH (thyroid-stimulating hormone), helping to restore normal thyroid hormone levels.

Dosage forms of liothyronine available

Liothyronine is available in the form of oral tablets.

Dosage of liothyronine

The initial dose of liothyronine is 25 micrograms (mcg) once a day, but this may vary depending on specific needs of the individual. If you take cholestyramine, colesevelam, or colestipol take them at least 4 to 5 hours before or after you take liothyronine. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for liothyronine use

Liothyronine should be taken exactly as directed by the healthcare provider. The specific instructions may include the timing of administration, dosage adjustments, and any necessary precautions.
If you miss a dose of your medication, take it as soon as you can. If it is almost time for you next dose, skip the missed dose and take your next dose at the regular time.

Warnings and contraindications for liothyronine

  • Liothyronine may have certain risks and potential side effects. It is important to discuss these with a healthcare provider before starting the medication
  • You will need regular thyroid function tests while you are taking this medication
  • Liothyronine should not be used as a weight-loss medication or for the treatment of obesity
  • Speak to your doctor before starting treatment with liothyronine if you have problems with your pituitary or adrenal gland (adrenal insufficiency), cardiovascular disease, heart failure, angina (chest pain), high blood pressure, a blood clotting disorder, diabetes or osteoporosis

Use of liothyronine if pregnant or planning pregnancy

The use of liothyronine during pregnancy should be discussed with a healthcare provider. The potential benefits and risks should be evaluated on an individual basis. Liothyronine passes into breast milk during breast feeding, but is not likely to harm the baby.

Possible side effects of liothyronine

In clinical trials, common side effects of liothyronine may include increased heart rate, palpitations, tremors, sweating, and nervousness. Serious adverse events are rare but can occur. Seek emergency medical help if you have a life-threatening allergic reaction to this medication.

Interactions with other drugs

Liothyronine may have drug interactions with other prescription drugs. It is important to speak to a healthcare professional for further medical advice and drug information about all the medications you are taking, including vitamins, minerals, or other dietary supplements, to avoid potential interactions.

Similar drugs to liothyronine

Other thyroid hormone replacement medications, such as levothyroxine, may be used as alternatives for the treatment of hypothyroidism.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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