laronidase
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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laronidase Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is laronidase available in?
laronidase is available as a 2.9 mg/5 mL vial for IV infusion.
What is laronidase used for?
laronidase is an enzyme replacement therapy and is used for the following:
- Certain forms of mucopolysaccharidosis type I (MPS I):
- Hurler and Hurler-Scheie forms
- Scheie form with moderate-to-severe symptoms
How does laronidase work?
laronidase works by replacing an enzyme that’s missing in some forms of mucopolysaccharidosis type I (MPS I). People with MPS I don’t have enough of or are missing an enzyme that’s needed to break down long chains of sugar molecules, which can lead to cell, tissue, or organ damage.
How do I take laronidase?
laronidase is only available as an intravenous (IV) infusion that’s administered by a healthcare provider. The recommended dose is 0.58 mg/kg of body weight, given as an infusion into the vein once a week. Your provider will determine the appropriate dose based on your body weight and health conditions.
Is it safe for me to take laronidase?
laronidase is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
laronidase Common Side Effects
Common side effects of laronidase:
- Infusion reactions (pyrexia, chills, blood
- pressure increased, tachycardia, and oxygen saturation decreased).
- Rash
- Upper respiratory tract infection
- Flushing
laronidase Serious Side Effects
Serious side effects are rare with laronidase. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction
- Acute respiratory failure
Effects of other drugs, drug classes and over-the-counter products on laronidase
- There are no major drug interactions listed for laronidase. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes laronidase?
Various FDA-approved generic manufacturers
Is laronidase safe in pregnancy?
It is not known if laronidase will harm your unborn baby. Tell your healthcare provider if you become pregnant while taking laronidase. An MPS I Registry has been established and pregnant women with MPS I should be encouraged to enroll in the pregnancy sub-registry. For more information, visit www.registrynxt.com or call 1-800-745-4447 ext. 15500.
What is the brand name for laronidase?
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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