HydroxychloroquinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Hydroxychloroquine Sulfate
    Generic for Plaquenil
    30 tablets $6.9 USD
    Save $66.30
  3. Hydroxychloroquine Sulfate
    Generic for Plaquenil
    75 tablets $13.5 USD
    Save $169.50
  4. Hydroxychloroquine Sulfate
    Generic for Plaquenil
    75 tablets $13.5 USD
    Save $169.50
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Do you need a prescription for hydroxychloroquine?

Yes, hydroxychloroquine is only available with a valid physician Rx.

How much is hydroxychloroquine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase hydroxychloroquine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for hydroxychloroquine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a hydroxychloroquine savings card?

Yes. Save up to 90% on your hydroxychloroquine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a hydroxychloroquine coupon provider in the US?

No. Now Patient does not provide hydroxychloroquine coupons or FREE hydroxychloroquine samples.

Do you accept commercial, Medicare or Medicaid coverage for hydroxychloroquine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much hydroxychloroquine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using hydroxychloroquine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much hydroxychloroquine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic hydroxychloroquine?

US brand name of hydroxychloroquine and manufacturer

Hydroxychloroquine is available in the US under the brand name Plaquenil. It is manufactured by various pharmaceutical companies.

UK brand name of hydroxychloroquine and manufacturer

Hydroxychloroquine is available in the UK under the generic name hydroxychloroquine. It is manufactured by various pharmaceutical companies.

Is hydroxychloroquine available in the UK on the NHS?

Hydroxychloroquine may be available on the NHS in the UK in certain circumstances and for specific indications. The availability and prescription of hydroxychloroquine on the NHS are subject to clinical guidelines and assessment by healthcare providers.

Prescription requirement for hydroxychloroquine

Hydroxychloroquine is a prescription medication and requires a prescription from a healthcare provider.

FDA approval of hydroxychloroquine

Hydroxychloroquine has received FDA approval for the treatment of certain autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, and malaria. It is important to note that the FDA has also issued a cautionary statement regarding the use of hydroxychloroquine for COVID-19, highlighting the need for careful consideration and evaluation of risks and benefits.

Active ingredient of hydroxychloroquine and mechanism of action

The active ingredient in hydroxychloroquine is hydroxychloroquine sulfate. It belongs to a class of medications called antimalarials which are also known as disease-modifying antirheumatic drugs (DMARDs). The exact mechanism of action of hydroxychloroquine in autoimmune diseases is not fully understood, but it is thought to affect the immune response and reduce inflammation.

Uses of hydroxychloroquine

Hydroxychloroquine is used for the treatment of several conditions, including:

  • Rheumatoid arthritis
  • Systemic lupus erythematosus (SLE)
  • Malaria (both treatment and prevention)

Hydroxychloroquine has been investigated for its potential use in treatment of COVID-19. Early in the pandemic, there was some speculation that hydroxychloroquine could be effective in treating COVID-19, leading to a surge in its popularity. However, it is important to note that the effectiveness of hydroxychloroquine in treating coronavirus disease (COVID-19) remains highly controversial. Several clinical trials and studies have been conducted to evaluate its efficacy, but the results have been mixed. Some studies have suggested that hydroxychloroquine may have some benefits in certain patient populations, while others have found no significant benefits or even potential harm. It is important to note that hydroxychloroquine should be prescribed and used according to specific indications and guidelines established by healthcare providers.

Forms of hydroxychloroquine

Hydroxychloroquine is available in the form of oral tablets. The specific strength and formulation will depend on the prescribed dosage and the manufacturer.

Dosage of hydroxychloroquine

The dosage of hydroxychloroquine will vary depending on the specific condition being treated, individual patient factors, and response to therapy. It is important to follow the dosage instructions provided by your healthcare provider. Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Precautions and warnings for hydroxychloroquine

  • Prior to starting hydroxychloroquine, inform your healthcare provider about any medical conditions, including eye problems, heart disease, liver disease, and any allergies to similar drugs such as chloroquine
  • Hydroxychloroquine can cause vision problems. Regular eye examinations may be recommended during treatment with hydroxychloroquine to monitor for potential ocular side effects
  • Hydroxychloroquine may interact with other medications, so it is important to inform your healthcare provider about all the medications you are taking
  • Avoid consuming alcohol while taking hydroxychloroquine
  • Take hydroxychloroquine at least 4 hours before or after using antacids
  • It is essential to follow your healthcare provider’s instructions regarding lifestyle modifications, including sun protection, if applicable
  • If an individual has previously experienced an allergic reaction or hypersensitivity to hydroxychloroquine or any of its components, its use should be avoided
  • Hydroxychloroquine can prolong the QT interval, which may lead to irregular heart rhythms, including a potentially life-threatening arrhythmia called torsades de pointes. Individuals with a history of heart problems, such as QT prolongation syndrome, bradycardia, or heart rhythm disturbances, should avoid the use of hydroxychloroquine
  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited condition that affects red blood cells. Hydroxychloroquine can cause hemolysis, or the breakdown of red blood cells, in individuals with this deficiency. Therefore, the use of hydroxychloroquine should be avoided in individuals with G6PD deficiency
  • Hydroxychloroquine can exacerbate psoriasis, a chronic skin condition characterized by red, itchy, and scaly patches. Individuals with psoriasis should exercise caution when using this medication
  • Hydroxychloroquine passes into breast milk. Speak to your doctor before breast feeding

Side effects of hydroxychloroquine

Common side effects of hydroxychloroquine may include:

  • Nausea
  • Diarrhea
  • Abdominal pain
  • Headache
  • Dizziness

Contact your healthcare provider if you experience any severe or persistent side effects.

Drug interactions 

Hydroxychloroquine may interact with certain medications, including other antimalarials, drugs affecting heart rhythm, and medications that suppress the immune system. It is important to inform your healthcare provider about all the medications you are taking to avoid potential adverse effects. Here are some examples of drugs that may interact with hydroxychloroquine:

  • There have been reports of potential interactions between hydroxychloroquine and azithromycin, an antibiotic commonly used to treat various bacterial infections. These drugs might increase the risk of an irregular heart rhythm, especially in individuals with existing heart conditions. If both medications are necessary, close monitoring is recommended
  • Digoxin is a medication commonly prescribed for heart conditions. There have been reports suggesting that hydroxychloroquine may increase the concentration of digoxin in the blood, potentially leading to toxicity. Regular monitoring of digoxin levels is advised when using both drugs together
  • Warfarin is an anticoagulant medication used to prevent blood clotting. Hydroxychloroquine may enhance the effects of warfarin, increasing the risk of bleeding. Careful monitoring of blood clotting parameters, such as the International Normalized Ratio (INR), is important when these drugs are used concomitantly
  • Methotrexate is a medication used to treat rheumatoid arthritis and other autoimmune conditions. Hydroxychloroquine may increase the toxicity of methotrexate, potentially leading to severe side effects. Close monitoring of blood counts and liver function is recommended when these medications are used together
  • Cyclosporine is an immunosuppressant medication commonly used after organ transplantation. Hydroxychloroquine may increase the concentration of cyclosporine in the blood, potentially leading to toxicity. Regular monitoring of cyclosporine levels is advised when using both drugs together
  • Hydroxychloroquine can affect blood glucose levels and may require adjustments in the dose of insulin or oral hypoglycemic agents used to control diabetes. Regular monitoring of blood sugar levels is important when these medications are used concurrently

It is essential to discuss with your healthcare provider any medications you are currently taking including prescription drugs, over-the-counter medication and supplements before starting hydrochlorothiazide. They can determine if there are any potential adverse effects and make necessary adjustments to your treatment plan.


Please note that this information is for educational purposes only and should not replace the advice of a healthcare professional.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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