Glyburide-metforminPrices, Coupons & Savings

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1. Medication
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   US ONLY
2. Glyburide-Metformin

   Generic for Glucovance

   Rx

   5mg-500mg

   30 tablets $4.2 USD

   30 tablets $4.2 USD - 0.14 USD/tablet
   Save $5.70

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Do you need a prescription for glyburide-metformin?

Yes, glyburide-metformin is only available with a valid physician Rx.

How much is glyburide-metformin without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase glyburide-metformin, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for glyburide-metformin in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a glyburide-metformin savings card?

Yes. Save up to 90% on your glyburide-metformin with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a glyburide-metformin coupon provider in the US?

No. Now Patient does not provide glyburide-metformin coupons or FREE glyburide-metformin samples.

Do you accept commercial, Medicare or Medicaid coverage for glyburide-metformin in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much glyburide-metformin?

US

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using glyburide-metformin. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much glyburide-metformin. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

UK

If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is glyburide-metformin?

Glyburide-metformin is a medication that is used to treat type 2 diabetes. It is a combination of two different drugs, glyburide and metformin, which work together to help control blood sugar levels in individuals with diabetes. Glyburide belongs to a class of medications called sulfonylureas, which stimulate the pancreas to produce more insulin. Insulin is a hormone that helps regulate blood sugar levels by allowing glucose (sugar) to enter cells and be used for energy. Metformin, on the other hand, belongs to a class of medications called biguanides. It works by decreasing the amount of glucose produced by the liver and improving the body’s response to insulin. By combining both glyburide and metformin, this medication can effectively lower blood sugar levels in people with type 2 diabetes. It helps to control blood sugar levels throughout the day, both after meals and while fasting. It is important to note that glyburide-metformin is not suitable for individuals with type 1 diabetes or diabetic ketoacidosis. It should also be used with caution in people with kidney or liver problems, as well as those with certain heart conditions.

FDA approval of glyburide-metformin

Glyburide-metformin is approved by the U.S. Food and Drug Administration (FDA) for the treatment of type 2 diabetes.

Active ingredients of glyburide-metformin

The active ingredients of glyburide-metformin are glyburide and metformin.

US brand name of glyburide-metformin and manufacturer

Glyburide-metformin is available in the United States under the brand name Glucovance. It is manufactured by Merck & Co., Inc.

UK brand name of glyburide-metformin and manufacturer

In the United Kingdom, glyburide-metformin is not available as a combination product. Glyburide is called glibenclamide in the UK.

Generic availability of glyburide-metformin

Generic versions of glyburide-metformin are available and are typically sold under the name glyburide-metformin.

Prescription requirement for glyburide-metformin

Glyburide-metformin is a prescription medication in the United States and the United Kingdom. It is important to consult a healthcare provider to determine if glyburide-metformin is appropriate for you and to receive the correct dosage instructions.

Availability of glyburide-metformin in the UK with NHS Prescription

Glyburide-metformin as a combination product is not available with a National Health Service (NHS) prescription in the United Kingdom.

Conditions treated by glyburide-metformin

Glyburide-metformin is primarily used for the management of type 2 diabetes mellitus, particularly when diet and exercise alone are not sufficient to control blood sugar levels.

How does glyburide-metformin work?

Glyburide-metformin is a medication that combines two different drugs, glyburide and metformin, in order to help control blood glucose levels in individuals with type 2 diabetes. It works through different mechanisms of action to achieve this goal. Glyburide belongs to a class of medications known as sulfonylureas. It works by stimulating the pancreas to release more insulin, which helps lower blood sugar levels. Insulin is a hormone that is responsible for regulating the amount of sugar (glucose) in the blood. By increasing insulin production, glyburide helps the body utilize glucose more effectively and reduce high blood sugar levels (hyperglycemia).

In contrast, metformin belongs to a class of medications called biguanides. It works by reducing the amount of glucose produced by the liver and improving the body’s response to insulin. Metformin also helps to decrease the absorption of glucose from the intestines. By reducing the amount of glucose produced by the liver and increasing insulin sensitivity, metformin helps to lower blood sugar levels and improve glycemic control. By combining glyburide and metformin into a single medication, glyburide-metformin provides a synergistic effect. The two drugs work together to target different aspects of blood sugar control, resulting in improved glycemic control for individuals with type 2 diabetes.

Forms of glyburide-metformin available

Glyburide-metformin is available as an oral tablet.

Dosage of glyburide-metformin

The dosage of glyburide-metformin may vary depending on individual factors, such as the severity of diabetes, response to treatment, and other medications being taken. It is important to follow the dosage instructions provided by the healthcare provider and not exceed the prescribed dose. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Directions for glyburide-metformin use

Glyburide-metformin is typically taken orally with meals. It is important to take glyburide-metformin exactly as prescribed by the healthcare provider and follow their instructions regarding the dosing schedule and any specific precautions. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Side effects of glyburide-metformin

Here are some common side effects of glyburide-metformin:

• One of the main side effects of glyburide-metformin is low blood sugar levels (hypoglycemia) This can cause symptoms such as dizziness, blurred vision, weakness, sweating, confusion, and hunger. It is important to monitor your blood sugar levels regularly and be aware of the signs of hypoglycemia
• Some people may experience gastrointestinal side effects, including nausea, vomiting, upset stomach and stomach pain. These symptoms are usually mild and may improve over time as your body adjusts to the medication. If the symptoms are severe or persistent, it is important to consult your doctor
• Weight gain is a potential side effect of glyburide-metformin. This may be due to the way the medication affects insulin and blood sugar levels. It is important to maintain a healthy diet and exercise regularly to help manage your weight
• In rare cases, some individuals may experience more serious side effects such as allergic reactions to glyburide-metformin. Symptoms of an allergic reaction may include rash, itching, swelling, severe dizziness, and trouble breathing. If you experience any of these symptoms, seek medical attention immediately

Warning and precautions

• If you have kidney disease or liver disease you may be at increased risk for metformin-related side effects, including lactic acidosis
• Stop taking this medication and seek immediate medical attention if you develop any of the following symptoms of lactic acidosis: unusual tiredness, severe drowsiness, chills, blue/cold skin, muscle pain and fast/difficult breathing
• People who have an enzyme deficiency known as glucose-6-phosphate dehydrogenase (G6PD) deficiency may develop hemolytic anemia with glyburide. Be sure to talk with your doctor if you have this enzyme deficiency
• Long-term treatment with metformin may lead to low vitamin B-12 levels. If you have ever had low vitamin B-12 levels, talk with your doctor

Drug interactions 

Glyburide-metformin may interact with certain medications, including other diabetes medications, certain antibiotics, and drugs that affect liver enzymes. It is important to inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential  adverse effects. It is important to always inform your healthcare provider of all your medical conditions and medications, including prescription drugs, over-the-counter drugs, herbal supplements, or vitamins while taking glyburide. They can provide you with the necessary information and guidance to ensure your safety and manage any potential.

Is glyburide-metformin safe to take if I am pregnant or planning on becoming pregnant?

Glyburide-metformin is not recommended for use during pregnancy. It is important to discuss with your healthcare provider the use of glyburide-metformin if you are pregnant or planning to become pregnant. Alternative treatment options may be considered.

Is glyburide-metformin safe to take if I am breastfeeding?

It is not recommended to take glyburide-metformin while breastfeeding. It is important to consult with a healthcare provider for individualized recommendations.

Sources

• FDA Prescribing Information for Glucovance (Glyburide-Metformin)
• NHS – Glyburide and Metformin
• WebMD – Glyburide-Metformin
• Drugs.com – Glyburide-Metformin