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Is the cost of your glyburide/metformin too expensive?

You may qualify for programs where you can pay as little as $0 per fill, subject to income and insurance status.

This content is intended for US audiences only

NowPatient offers cost effective access to glyburide/metformin for everyone including those who are uninsured, those who have commercial insurance as well as those who are enrolled into state or federal programs like Medicaid, Medicare Part D, full Low Income Subsidy (LIS, “Extra Help”), TRICARE or Veterans (VA) Benefits.

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Table of contents
OverviewWhat can I do if I am commercially insured but cannot afford my glyburide/metformin?What can I do if I am uninsured and cannot afford my glyburide/metformin?What can I do if I am insured with Medicare and cannot afford my glyburide/metformin?Am I eligible for the Rx Advantage Card and how much does glyburide/metformin cost without insurance?What will my out-of-pocket cost be for glyburide/metformin when using the Rx Advantage Card?Is it legal for me to pay cash for glyburide/metformin even though I have insurance?Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?Does the Rx Advantage Card work with Commercial Insurance?How do I check prices for glyburide/metformin and how do I use the Rx Advantage Card?Do I need to pay for the Rx Advantage Card?Is there a glyburide/metformin co-pay program?Is there a glyburide/metformin Patient Assistance Program (PAP)?What should I do if I take too much glyburide/metformin?What are the benefits of NowPatient?What is glyburide/metformin?FDA approval of glyburide/metforminActive ingredients of glyburide/metforminUS brand name of glyburide/metformin and manufacturerUK brand name of glyburide/metformin and manufacturerGeneric availability of glyburide/metforminPrescription requirement for glyburide/metforminAvailability of glyburide/metformin in the UK with NHS PrescriptionConditions treated by glyburide/metforminHow does glyburide/metformin work?Forms of glyburide/metformin availableDosage of glyburide/metforminDirections for glyburide/metformin useSide effects of glyburide/metforminWarning and precautionsDrug interactions Is glyburide/metformin safe to take if I am pregnant or planning on becoming pregnant?Is glyburide/metformin safe to take if I am breastfeeding?SourcesPeople also asked
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Medically reviewed by Navin Khosla, BPharm and written by Rajive Patel, BPharm - Updated on 25 Jan 2024
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What can I do if I am commercially insured but cannot afford my glyburide/metformin?

If you are commercially insured and you cannot afford your copay or co-insurance you can opt for purchasing glyburide/metformin outside of your plan using the Rx Advantage card, with costs that are usually lower than a typical plan copay. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

If you cannot afford the cash price possibly due to income constraints, then there is the option of applying to state assistance programs like Medicaid. Often, you may be able to receive your glyburide/metformin without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am uninsured and cannot afford my glyburide/metformin?

If you cannot afford the cash price of glyburide/metformin using the Rx Advantage card then there is the option of applying to state programs like Medicaid. Often, you may be able to receive your glyburide/metformin without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am insured with Medicare and cannot afford my glyburide/metformin?

If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have a number of options:

Option

Savings Information

RX ADVANTAGE CARD

You can use the Rx Advantage to purchase the medication outside of your plan at prices that may be lower than you copay or co-insurance element. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

LOW INCOME SUBSIDY

If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

MEDICAID

Alternatively, you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

Am I eligible for the Rx Advantage Card and how much does glyburide/metformin cost without insurance?

Our website gives savings options to customers who wish to purchase glyburide/metformin, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.

What will my out-of-pocket cost be for glyburide/metformin when using the Rx Advantage Card?

Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for glyburide/metformin using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.

Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.

Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?

No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket glyburide/metformin cash price you pay can be typically cheaper than your plan copay.

Does the Rx Advantage Card work with Commercial Insurance?

We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket glyburide/metformin cash price you pay can be typically cheaper than your plan copay.

How do I check prices for glyburide/metformin and how do I use the Rx Advantage Card?

You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your glyburide/metformin Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.

Do I need to pay for the Rx Advantage Card?

No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.

Is there a glyburide/metformin co-pay program?

Generic medications like glyburide/metformin do not have co-pay card savings options. A Copay program, if available, would normally be for the brand name version of glyburide/metformin. You can search the brand name of glyburide/metformin and check to see if a co-pay program exists. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.

Is there a glyburide/metformin Patient Assistance Program (PAP)?

Generic medications like glyburide/metformin do not have PAP savings options. A Patient assistance program, if available would normally be for the brand name version of glyburide/metformin. You can search the brand name of glyburide/metformin and check to see if a co-PAP exists. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.

What should I do if I take too much glyburide/metformin?

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using glyburide/metformin. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much glyburide/metformin. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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What is glyburide/metformin?

glyburide/metformin is a medication that is used to treat type 2 diabetes. It is a combination of two different drugs, glyburide and metformin, which work together to help control blood sugar levels in individuals with diabetes. Glyburide belongs to a class of medications called sulfonylureas, which stimulate the pancreas to produce more insulin. Insulin is a hormone that helps regulate blood sugar levels by allowing glucose (sugar) to enter cells and be used for energy. Metformin, on the other hand, belongs to a class of medications called biguanides. It works by decreasing the amount of glucose produced by the liver and improving the body’s response to insulin. By combining both glyburide and metformin, this medication can effectively lower blood sugar levels in people with type 2 diabetes. It helps to control blood sugar levels throughout the day, both after meals and while fasting. It is important to note that glyburide/metformin is not suitable for individuals with type 1 diabetes or diabetic ketoacidosis. It should also be used with caution in people with kidney or liver problems, as well as those with certain heart conditions.

FDA approval of glyburide/metformin

glyburide/metformin is approved by the U.S. Food and Drug Administration (FDA) for the treatment of type 2 diabetes.

Active ingredients of glyburide/metformin

The active ingredients of glyburide/metformin are glyburide and metformin.

US brand name of glyburide/metformin and manufacturer

glyburide/metformin is available in the United States under the brand name Glucovance. It is manufactured by Merck & Co., Inc.

UK brand name of glyburide/metformin and manufacturer

In the United Kingdom, glyburide/metformin is not available as a combination product. Glyburide is called glibenclamide in the UK.

Generic availability of glyburide/metformin

Generic versions of glyburide/metformin are available and are typically sold under the name glyburide/metformin.

Prescription requirement for glyburide/metformin

glyburide/metformin is a prescription medication in the United States and the United Kingdom. It is important to consult a healthcare provider to determine if glyburide/metformin is appropriate for you and to receive the correct dosage instructions.

Availability of glyburide/metformin in the UK with NHS Prescription

glyburide/metformin as a combination product is not available with a National Health Service (NHS) prescription in the United Kingdom.

Conditions treated by glyburide/metformin

glyburide/metformin is primarily used for the management of type 2 diabetes mellitus, particularly when diet and exercise alone are not sufficient to control blood sugar levels.

How does glyburide/metformin work?

glyburide/metformin is a medication that combines two different drugs, glyburide and metformin, in order to help control blood glucose levels in individuals with type 2 diabetes. It works through different mechanisms of action to achieve this goal. Glyburide belongs to a class of medications known as sulfonylureas. It works by stimulating the pancreas to release more insulin, which helps lower blood sugar levels. Insulin is a hormone that is responsible for regulating the amount of sugar (glucose) in the blood. By increasing insulin production, glyburide helps the body utilize glucose more effectively and reduce high blood sugar levels (hyperglycemia).

In contrast, metformin belongs to a class of medications called biguanides. It works by reducing the amount of glucose produced by the liver and improving the body’s response to insulin. Metformin also helps to decrease the absorption of glucose from the intestines. By reducing the amount of glucose produced by the liver and increasing insulin sensitivity, metformin helps to lower blood sugar levels and improve glycemic control. By combining glyburide and metformin into a single medication, glyburide/metformin provides a synergistic effect. The two drugs work together to target different aspects of blood sugar control, resulting in improved glycemic control for individuals with type 2 diabetes.

Forms of glyburide/metformin available

glyburide/metformin is available as an oral tablet.

Dosage of glyburide/metformin

The dosage of glyburide/metformin may vary depending on individual factors, such as the severity of diabetes, response to treatment, and other medications being taken. It is important to follow the dosage instructions provided by the healthcare provider and not exceed the prescribed dose. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Directions for glyburide/metformin use

glyburide/metformin is typically taken orally with meals. It is important to take glyburide/metformin exactly as prescribed by the healthcare provider and follow their instructions regarding the dosing schedule and any specific precautions. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Side effects of glyburide/metformin

Here are some common side effects of glyburide/metformin:

  • One of the main side effects of glyburide/metformin is low blood sugar levels (hypoglycemia) This can cause symptoms such as dizziness, blurred vision, weakness, sweating, confusion, and hunger. It is important to monitor your blood sugar levels regularly and be aware of the signs of hypoglycemia
  • Some people may experience gastrointestinal side effects, including nausea, vomiting, upset stomach and stomach pain. These symptoms are usually mild and may improve over time as your body adjusts to the medication. If the symptoms are severe or persistent, it is important to consult your doctor
  • Weight gain is a potential side effect of glyburide/metformin. This may be due to the way the medication affects insulin and blood sugar levels. It is important to maintain a healthy diet and exercise regularly to help manage your weight
  • In rare cases, some individuals may experience more serious side effects such as allergic reactions to glyburide/metformin. Symptoms of an allergic reaction may include rash, itching, swelling, severe dizziness, and trouble breathing. If you experience any of these symptoms, seek medical attention immediately

Warning and precautions

  • If you have kidney disease or liver disease you may be at increased risk for metformin-related side effects, including lactic acidosis
  • Stop taking this medication and seek immediate medical attention if you develop any of the following symptoms of lactic acidosis: unusual tiredness, severe drowsiness, chills, blue/cold skin, muscle pain and fast/difficult breathing
  • People who have an enzyme deficiency known as glucose-6-phosphate dehydrogenase (G6PD) deficiency may develop hemolytic anemia with glyburide. Be sure to talk with your doctor if you have this enzyme deficiency
  • Long-term treatment with metformin may lead to low vitamin B-12 levels. If you have ever had low vitamin B-12 levels, talk with your doctor

Drug interactions 

glyburide/metformin may interact with certain medications, including other diabetes medications, certain antibiotics, and drugs that affect liver enzymes. It is important to inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential  adverse effects. It is important to always inform your healthcare provider of all your medical conditions and medications, including prescription drugs, over-the-counter drugs, herbal supplements, or vitamins while taking glyburide. They can provide you with the necessary information and guidance to ensure your safety and manage any potential.

Is glyburide/metformin safe to take if I am pregnant or planning on becoming pregnant?

glyburide/metformin is not recommended for use during pregnancy. It is important to discuss with your healthcare provider the use of glyburide/metformin if you are pregnant or planning to become pregnant. Alternative treatment options may be considered.

Is glyburide/metformin safe to take if I am breastfeeding?

It is not recommended to take glyburide/metformin while breastfeeding. It is important to consult with a healthcare provider for individualized recommendations.

Sources

  • FDA Prescribing Information for Glucovance (glyburide/metformin)
  • NHS – Glyburide and Metformin
  • WebMD – glyburide/metformin
  • Drugs.com – glyburide/metformin
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