FluocinolonePrices, Coupons & Savings

FDA badge
Looking for ways to save up to 90%* on your FDA-approved branded and generic medications?
You could enjoy savings using Now Patient’s mail-order online pharmacy or the Now Patient Rx Advantage Card at over 65,000 pharmacies.
US Flag
United States
*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

Mail Order Pharmacy

  1. Medication
    You save
    US Flag
  2. Fluocinolone Acetonide Body
    Generic for Derma-Smoothe/FS Body
    118.28mL bottle of oils $24.85 USD
    Save $79.14
Now Patient Parcel

Or join now to use our savings card

Savings Card

Save up to 90% of your branded or generic medications using the Now Patient Rx Advantage Card

Do you need a prescription for fluocinolone?

Yes, fluocinolone is only available with a valid physician Rx.

How much is fluocinolone without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase fluocinolone, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for fluocinolone in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a fluocinolone savings card?

Yes. Save up to 90% on your fluocinolone with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a fluocinolone coupon provider in the US?

No. Now Patient does not provide fluocinolone coupons or FREE fluocinolone samples.

Do you accept commercial, Medicare or Medicaid coverage for fluocinolone in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much fluocinolone?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using fluocinolone. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much fluocinolone. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic fluocinolone?

Generic fluocinolone refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of fluocinolone

Fluocinolone is approved by the U.S. Food and Drug Administration (FDA) for various dermatological conditions, including eczema, psoriasis, and allergic reactions.

Active ingredient of fluocinolone

The active ingredient of fluocinolone is fluocinolone acetonide.

US brand name of fluocinolone and manufacturer

Fluocinolone is available in the US under various brand names, including Synalar and Derma-Smoothe/FS. The manufacturers may vary depending on the brand names.

UK brand name of fluocinolone and manufacturer

In the UK, fluocinolone is available under various brand names, including Synalar. The manufacturer may vary depending on the brand name.

Prescription requirement for fluocinolone

A prescription (Rx) is required for fluocinolone in both the US and the UK.

Availability of fluocinolone in the UK with NHS prescription

Fluocinolone is available in the UK with an NHS prescription.

Conditions treated by fluocinolone

Fluocinolone is commonly used to treat a range of inflammatory skin conditions, including dermatitis, eczema, and psoriasis. It is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions. Additionally, ongoing research explores the potential off-label uses of fluocinolone in emerging areas of dermatology.

How does fluocinolone work?

Fluocinolone belongs to the class of medications called corticosteroids. It works by reducing inflammation, itching, and redness associated with skin conditions.

Forms of fluocinolone available

Fluocinolone is available in various forms, including topical creams, ointments, and topical solutions.

Dosage of fluocinolone

The dosage of fluocinolone may vary depending on the specific skin condition being treated, the severity of the condition, and other individual factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Directions for fluocinolone use

Fluocinolone should be applied as directed by the healthcare provider or as indicated on the product packaging. It should be applied to the affected area of the skin and gently rubbed in.

Topical corticosteroids are generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition. In hairy sites, the hair should be parted to allow direct contact with the lesion.

Store at room temperature. Do not freeze. Keep all medications away from children and pets.

Warnings and precautions for fluocinolone

  • Fluocinolone should not be used on open wounds or areas with skin infections
  • Fluocinolone is contraindicated in patients with hypersensitivity to the drug or any of its components
  • Caution should be exercised when using fluocinolone in patients with active untreated infections, as it may suppress the immune response. Additionally, long-term use of a steroid like fluocinolone on large areas of the body should be avoided due to potential systemic absorption and adverse effects
  • Monitor for signs of adrenal insufficiency during treatment with fluocinolone, especially when used for prolonged periods or on extensive areas of skin
  • Don’t use fluocinolone cream to treat perioral dermatitis (rash around the mouth)
  • Prolonged use of fluocinolone may cause side effects, such as thinning of the skin, skin discolouration, and increased risk of infections
  • Use with caution with patients with preexisting skin atrophy
  • It is important to avoid contact with the eyes when using fluocinolone
  • Parents of pediatric patients should be advised not to use tight-fitting diapers or plastic pants on a child being treated in the diaper area, as these garments may constitute occlusive dressings
  • Adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings.These reactions include: burning perioral dermatitis, contact dermatitis, folliculitis skin atrophy and striae
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding before starting treatment

Drug interactions of fluocinolone

There are some potential interactions to consider:

  • Using multiple topical medications simultaneously can increase the absorption of fluocinolone through the skin, leading to an increased risk of side effects. It is important to inform your healthcare provider about any other topical products you are using, including over-the-counter creams, ointments, or lotions
  • Concurrent use of oral or injectable corticosteroids with fluocinolone may increase the risk of systemic side effects such as adrenal suppression, Cushing’s syndrome (roundness of your face, weight gain, or a hump between your shoulders) and immunosuppression. Close monitoring and adjustment of dosage may be required if both medications are necessary
  • Concurrent use of fluocinolone and anticoagulants e.g. warfarin may increase the risk of bleeding. It is important to closely monitor for any signs of bleeding, such as easy bruising or prolonged bleeding from cuts or injuries, and seek medical attention if necessary

Drug interactions may change how your medications work or increase your risk for serious side effects. Always inform a healthcare professional about all prescription drugs, supplements, and vitamins you are taking before starting fluocinolone. They can provide guidance on any potential interactions and adjust your medication or dosages if necessary.

Possible side effects of fluocinolone

Common side effects of fluocinolone may include burning, itching, irritation, or redness at the application site. If these side effects persist or worsen, it is important to contact a healthcare provider.

Similar drugs to fluocinolone

Other corticosteroids, such as hydrocortisone and betamethasone, may be used as alternatives to fluocinolone for the treatment of inflammatory skin conditions.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives.  Our service gives you access to smart features & resources that can help empower you to take control of your health and improve your health outcomes.  All this, in one place, for FREE.  We strive to bring a fresh perspective to managing health. Not play by the rules. Now Patient can be accessed by downloading the App or using your web browser.

A mobile phone with a health app and a pollen meter.
Your Questions Answered
For your peace of mind, we can answer your health questions quickly
If you want to learn more about the range of services that we provide which can help manage and improve your health, then just click the button below.
Find your answers