Used for Hypertension

View epoprostenol savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or epoprostenol Patient Assistance Program.

Programs are suitable for individuals who want to buy epoprostenol without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

  • Qualified

    Rx Advantage Card

    A hand holding a dark-colored prescription savings card with various ID numbers and the label "Rx Advantage." Text below states the card is not insurance and cannot be used for Medicare or Medicaid.

    Save up to 90%

  • Unavailable

    Canadian Prescription Savings

    Manufactured by
    Powered by
    Prescription Help Logo
  • Unavailable

    Drug Coupons

    A hand holds a Copay Savings Card that states eligible patients with commercial insurance may pay as little as $0 per tube for Opzelura.
  • Unavailable

    Patient Assistance Programs

    A picture of a patient assistance application form
Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

Learn more about epoprostenol

What dosages is epoprostenol available in?

What dosages is epoprostenol available in?

epoprostenol is available as a 0.5 mg (500,000 ng) or 1.5 mg
(1,500,000 ng) injection for IV use.

What is epoprostenol used for?

What is epoprostenol used for?

epoprostenol is a prostacyclin vasodilator and is used to treat pulmonary arterial hypertension (PAH).

How does epoprostenol work?

How does epoprostenol work?

epoprostenol is a prostacyclin vasodilator. Prostacyclins work by relaxing muscles in the arteries (blood vessels), which leads to vasodilation. Vasodilation means that the blood vessels widen, which allows more blood to flow through them. In addition, prostacyclins prevent platelets, pieces of cells found in the blood, from sticking to each other. This also helps improve blood flow. PAH occurs when blood can’t flow freely through the arteries in your lungs. This raises the blood pressure in your lungs, causing your heart to have to work harder to send blood to your lungs for oxygen. epoprostenol helps with PAH because it improves the blood flow in your arteries.

How do I take epoprostenol?

How do I take epoprostenol?

epoprostenol is an intravenous (IV) infusion that’s given through a pump programmed to deliver your dose over a certain period of time. Before starting epoprostenol, your provider will typically insert a catheter into a large vein near the heart. Your care team will train you on how to use the pump at home. Your provider will calculate the dose based on your body weight. The typical starting dose is 2 nanograms (ng) per kg of body weight per minute (2 ng/kg/min). The dose can be adjusted by your provider based on your response to the medication.

Is it safe for me to take epoprostenol?

Is it safe for me to take epoprostenol?

epoprostenol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:

  • Congestive heart failure due to severe left ventricular systolic dysfunction
  • Pulmonary edema
  • Hypersensitivity to the drug or to structurally related compounds
epoprostenol Common Side Effects

epoprostenol Common Side Effects

Common side effects of epoprostenol:

  • Flushing
  • Headache
  • Nausea/vomiting
  • Low blood pressure
  • Anxiety, nervousness, or agitation
  • Chest pain
epoprostenol Serious Side Effects

epoprostenol Serious Side Effects

Serious side effects are rare with epoprostenol. Contact your healthcare provider immediately if you experience any of the following.

  • Excess fluid in the lungs: shortness of breath, cough, chest pain, fatigue
  • Bleeding problems: unusual or easy bleeding or bruising, vomiting or coughing up blood, blood in your urine or stool
Effects of other drugs, drug classes and over-the-counter products on epoprostenol

Effects of other drugs, drug classes and over-the-counter products on epoprostenol

The following medications may interact with epoprostenol:

  • Diuretics, antihypertensive agents, or other vasodilators: reduction in blood pressure
  • Antiplatelet agents or anticoagulants: increase the risk of bleeding
  • Patients on digoxin: elevations of digoxin concentrations clinically significant in patients prone to digoxin toxicity
Who makes epoprostenol?

Who makes epoprostenol?

Various FDA-approved generic manufacturers

Is epoprostenol safe in pregnancy?

Is epoprostenol safe in pregnancy?

It is not known if epoprostenol will harm your unborn baby. epoprostenol should be used during pregnancy only if the potential benefit justifies the potential risk to fetus.


What to do if you missed your epoprostenol dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
dollar sign

Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

FAQ logo

People Asked

Now Patient Data Security

Data Security

Our Commitment to You.

Find out moreNow Patient Data SecurityNow Patient Data Security

What is NowPatient

Telehealth and Online Pharmacy

NowPatient is a licensed online pharmacy and doctor service that is available around the world. Our service is FREE and packed with valuable features that can benefit your health such as medication reminders, educational blogs, medically approved symptoms checker, UK NHS online pharmacyprivate treatment plansRx Advantage cardhealth conditions information, affordable medications options, genetic testinghome test kitshealth riskspollen meterair quality monitor, weight loss plans, drug savings programs and lots more!

A laptop screen displaying a health dashboard with widgets showing health profile, notifications, personalized health tools, and favorite widgets including body mass index and weight loss tracking.


To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.

Download our app today

A collage showing a map with pharmacies, a questionnaire, medication details, and a person video chatting on a screen.

Can I trust NowPatient

Meet our medical team

We are a passionate group of clinicians and medical writers covering a broad range of specialities with experience operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process

Your Questions Answered

For your peace of mind, we can answer your questions quickly

We have a comprehensive list of FAQ’s on each feature page. Alternatively, for broader questions around our service just click the button below.
Find your answers