eplerenone
Used for Heart Failure and Hypertension
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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eplerenone Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is eplerenone available in?
eplerenone is available as a 25 mg and 50 mg oral tablet.
What is eplerenone used for?
eplerenone is an aldosterone receptor antagonist and is used to treat heart failure after a heart attack and high blood pressure.
How does eplerenone work?
eplerenone is a mineralocorticoid (aldosterone) antagonist. Aldosterone is a natural hormone in the body that normally raises your blood pressure by increasing the amount of salt and water in your bloodstream. So by blocking aldosterone, eplerenone helps your body get rid of extra salt and water, which then lowers your blood pressure. It’s unclear how exactly eplerenone helps with heart failure. But it’s thought that the medication helps protect the heart. This will help reduce the risk of death in people with heart failure.
How do I take eplerenone?
eplerenone is typically dosed as 25 mg to 50 mg by mouth once daily. The max dose is 50 mg by mouth once or twice daily, depending on the condition being treated.
Is it safe for me to take eplerenone?
eplerenone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a serum potassium >5.5 mEq/L at initiation, creatinine clearance ≤30 mL/min, have type 2 diabetes with microalbuminuria, a serum creatinine >2.0 mg/dL in males, >1.8 mg/dL in females, a creatinine clearance <50 mL/min with hypertension, or are taking a strong CYP3A inhibitor, potassium supplement, or potassium-sparing diuretic.
eplerenone Common Side Effects
Common side effects of eplerenone include:
- Digestive system problems
- Nervous system problems
- Urinary tract problems
- Shortness of breath
- Skin problems
- Mental health problems
- Cough
eplerenone Serious Side Effects
Serious side effects are rare with eplerenone. Contact your healthcare provider immediately if you experience any of the following.
- High potassium (hyperkalemia): irregular heart beat, nausea, muscle pain and weakness, numbness and tingling
Effects of other drugs, drug classes and over-the-counter products on eplerenone
The following medications may interact with eplerenone:
- CYP3A Inhibitors: In post-MI HFrEF patients do not exceed 25 mg once daily when used with moderate CYP3A inhibitors (e.g., verapamil, erythromycin, saquinavir, fluconazole). In patients with hypertension initiate at 25 mg once daily. For inadequate blood pressure response, dosing may be increased to a maximum of 25 mg twice daily.
Who makes eplerenone?
Various FDA-approved generic manufacturers
Is eplerenone safe in pregnancy?
It is not known if eplerenone will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.
What to do if you missed your eplerenone dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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If I have federal, state or commercial insurance and none of the eplerenone prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
What is the drug eplerenone used for?
Does eplerenone help with anxiety?
Can you eat bananas while taking eplerenone?
What should I monitor when taking eplerenone?
Does eplerenone increased urination?
What is the only thing eplerenone binds to?
Is eplerenone a spironolactone?
Who should not take eplerenone?
Which is better spironolactone or eplerenone?
Can you take spironolactone and eplerenone together?
Is eplerenone more expensive than spironolactone?
Is spironolactone more potent than eplerenone?
Is eplerenone a aldosterone blocker?
What type of diuretic is eplerenone?
Does eplerenone reduce anxiety?
What food interactions does eplerenone have?
Can you eat grapefruit while taking eplerenone?
What is equivalent to eplerenone?
Does eplerenone spare potassium?
Is eplerenone hard on kidneys?
What to avoid when taking eplerenone?
Does eplerenone cause weight gain?
What is a common side effect of eplerenone spironolactone?
Does eplerenone make you pee?
What is the main advantage of eplerenone over spironolactone?
Is eplerenone a good diuretic?
Does eplerenone affect the liver?
Does eplerenone cause water retention?
What is the mortality rate for eplerenone for heart failure?
Is eplerenone better than furosemide?
What medications are hardest on your kidneys?
Does eplerenone improve ejection fraction?
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