eplerenone
Used for Hypertension and Heart Failure
Are you tired of high medication costs? Our service offers unbeatable savings on your eplerenone prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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eplerenone key facts
What dosages is eplerenone available in?
eplerenone is available as a 25 mg and 50 mg oral tablet.
What is eplerenone used for?
eplerenone is an aldosterone receptor antagonist and is used to treat heart failure after a heart attack and high blood pressure.
How does eplerenone work?
eplerenone is a mineralocorticoid (aldosterone) antagonist. Aldosterone is a natural hormone in the body that normally raises your blood pressure by increasing the amount of salt and water in your bloodstream. So by blocking aldosterone, eplerenone helps your body get rid of extra salt and water, which then lowers your blood pressure. It’s unclear how exactly eplerenone helps with heart failure. But it’s thought that the medication helps protect the heart. This will help reduce the risk of death in people with heart failure.
How do I take eplerenone?
eplerenone is typically dosed as 25 mg to 50 mg by mouth once daily. The max dose is 50 mg by mouth once or twice daily, depending on the condition being treated.
Is it safe for me to take eplerenone?
eplerenone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a serum potassium >5.5 mEq/L at initiation, creatinine clearance ≤30 mL/min, have type 2 diabetes with microalbuminuria, a serum creatinine >2.0 mg/dL in males, >1.8 mg/dL in females, a creatinine clearance <50 mL/min with hypertension, or are taking a strong CYP3A inhibitor, potassium supplement, or potassium-sparing diuretic.
eplerenone Common Side Effects
Common side effects of eplerenone include:
- Digestive system problems
- Nervous system problems
- Urinary tract problems
- Shortness of breath
- Skin problems
- Mental health problems
- Cough
eplerenone Serious Side Effects
Serious side effects are rare with eplerenone. Contact your healthcare provider immediately if you experience any of the following.
- High potassium (hyperkalemia): irregular heart beat, nausea, muscle pain and weakness, numbness and tingling
Effects of other drugs, drug classes and over-the-counter products on eplerenone
The following medications may interact with eplerenone:
- CYP3A Inhibitors: In post-MI HFrEF patients do not exceed 25 mg once daily when used with moderate CYP3A inhibitors (e.g., verapamil, erythromycin, saquinavir, fluconazole). In patients with hypertension initiate at 25 mg once daily. For inadequate blood pressure response, dosing may be increased to a maximum of 25 mg twice daily.
Who makes eplerenone?
Various FDA-approved generic manufacturers
Is eplerenone safe in pregnancy?
It is not known if eplerenone will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my eplerenone prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your eplerenone prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient eplerenone savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient eplerenone savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for eplerenone | Canadian Prescription Savings* for eplerenone | eplerenone Drug Coupon* | eplerenone Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of eplerenone?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for eplerenone | Canadian Prescription Savings* for eplerenone | eplerenone Drug Coupon* | eplerenone Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the eplerenone savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the eplerenone drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for eplerenone, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the eplerenone prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, eplerenone is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed eplerenone for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the eplerenone prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the eplerenone prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for eplerenone
If you are having trouble paying for your eplerenone medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for eplerenone you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- eplerenone is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers eplerenone
- If eplerenone is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for eplerenone
If you are having trouble paying for your eplerenone medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for eplerenone you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers eplerenone
- If eplerenone is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for eplerenone
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your eplerenone treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for eplerenone you will need to meet the following criteria:
- You must be currently insured and have coverage for eplerenone
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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In the UK, we are located at:
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NowPatient
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Suite 4200 #1263
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Who owns NowPatient?
NowPatient is owned and operated by Infohealth Ltd, a licensed online pharmacy with services spanning the UK, US and Rest of the World. Infohealth Ltd is registered in England and Wales under company number 04004930 and our registered office is at Lynwood House, 373 – 375 Station Road, Harrow, England, HA1 2AW.
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Can you tell me more about your NHS online pharmacy?
NowPatient’s Pharmaceutical services in the UK are provided by Infohealth Limited trading as ‘Infohealth Pharmacy’.
Our dispensing pharmacy is regulated and authorized for internet sales by the General Pharmaceutical Council (GPhC), registration number 1036487. You can view our license credentials on the General Pharmaceutical Council website. Our superintendent pharmacist who is responsible for the safe and effective oversight of medicines supplies is Mr Amish Patel (Registration Number 2042705).
Medicines are not ordinary items of commerce. All medicines or healthcare product sales are made under the supervision of a registered pharmacist who is licensed by the GPhC. At all times, we endeavour to provide a professional and transparent service whose primary goal is to ensure that the best interests of the patient are served.
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NowPatient prescribing services are run by Infohealth Limited. The Clinical Safety Officer and nominated individual is Mr Navin Khosla.
Can you tell me more about NowPatient’s US services?
Our head of US services is Dr. Jamie Winn.
You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
We do not provide any prescribing services or dispensing services in the United States.
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