DexamethasonePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Dexamethasone
    Generic for Decadron
    30 tablets $15.6 USD
    Save $24.60
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Do you need a prescription for dexamethasone?

Yes, dexamethasone is only available with a valid physician Rx.

How much is dexamethasone without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase dexamethasone, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for dexamethasone in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a dexamethasone savings card?

Yes. Save up to 90% on your dexamethasone with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a dexamethasone coupon provider in the US?

No. Now Patient does not provide dexamethasone coupons or FREE dexamethasone samples.

Do you accept commercial, Medicare or Medicaid coverage for dexamethasone in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much dexamethasone?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using dexamethasone. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much dexamethasone. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic dexamethasone?

Generic dexamethasone refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of dexamethasone

Dexamethasone is approved by the U.S. Food and Drug Administration (FDA) for various indications, including the treatment of inflammatory and immune-related conditions.

Active ingredient of dexamethasone

The active ingredient of dexamethasone is dexamethasone.

US brand name of dexamethasone and manufacturer

Dexamethasone is available in the US under various brand names, including Decadron and DexPak. The manufacturers may vary depending on the brand names.

UK brand name of dexamethasone and manufacturer

In the UK, dexamethasone is available under various brand names, including Dexafree, Dropodex, Eythalm, Maxidex. The manufacturer may vary depending on the brand name.

Prescription requirement for dexamethasone

A prescription (Rx) is required for dexamethasone in both the US and the UK.

Availability of dexamethasone in the UK with NHS prescription

Dexamethasone is available in the UK with an NHS prescription.

Conditions treated by dexamethasone

Here are some of the conditions that dexamethasone is used to treat:

  • Inflammatory conditions: Dexamethasone is often prescribed to reduce inflammation in the body. It can be used to treat conditions like arthritis, bursitis, tendinitis, and other inflammatory joint disorders
  • Allergic reactions: Dexamethasone is effective in managing severe allergic reactions, including allergic rhinitis, asthma, and severe allergic skin reactions like hives or angioedema
  • Asthma: As an anti-inflammatory medication, dexamethasone can help control and prevent asthma attacks by reducing inflammation in the airways
  • Autoimmune disorders: Dexamethasone is frequently used in the treatment of various autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus (SLE), and multiple sclerosis
  • Organ transplants: After an organ transplant, dexamethasone is commonly prescribed to suppress the immune system and prevent the body from rejecting the new organ
  • Cancer: In cancer treatment, dexamethasone can be used to manage symptoms like nausea, vomiting, and swelling caused by chemotherapy drugs. It may also be used to alleviate symptoms of certain types of cancer

How does dexamethasone work?

Dexamethasone belongs to a class of medications called steroids (also known as corticosteroids or glucocorticoids). It works by reducing inflammation and suppressing the immune response in the body. This helps alleviate symptoms associated with inflammatory and immune-related conditions.

Forms of dexamethasone available

Dexamethasone is available in various forms, including oral tablets, injections, and eye/ear drops.

Dosage of dexamethasone

The dosage of dexamethasone may vary depending on the specific condition being treated, the severity of the condition, and other individual factors. It is important to follow the recommended dosage instructions the healthcare provider provides.
If you take dexamethasone once a day and miss a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose and take the next one at the usual time.
If you take it 2 or 3 times a day, take the missed dose as soon as you remember, unless it’s less than 2 hours until your next dose. In this case, skip the missed dose and take the next one as normal.
Do not take a double dose to make up for a forgotten one.

Directions for dexamethasone use

Dexamethasone should be taken or administered as directed by the healthcare provider. The specific instructions may include the timing of administration, dosage adjustments, and any necessary precautions.
Store dexamethasone tablets at room temperature away from moisture and heat.

Warnings and precautions for dexamethasone

  • Dexamethasone should be used with caution and under the supervision of a healthcare provider, as it can have potential side effects and interactions with other medications
  • Abrupt discontinuation of dexamethasone should be avoided, and the dosage should be gradually tapered off as directed by the healthcare provider
  • Taking dexamethasone tablets or liquid can mean you’re more likely to get infections. Tell your doctor if you get an infection, such as coronavirus (COVID-19), or if you come into contact with anyone who has measles, chickenpox or shingles while you’re taking dexamethasone
  • Always inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal supplements, to ensure safe and effective treatment

Use of dexamethasone if pregnant or planning pregnancy

The use of dexamethasone during pregnancy and breastfeeding should be discussed with a healthcare provider. The potential benefits and risks should be evaluated on an individual basis.

Possible side effects of dexamethasone

In clinical trials some common adverse effects of dexamethasone included:

  • Dexamethasone can stimulate appetite, leading to increased food intake and potential weight gain
  • This medication can cause fluid retention, leading to swelling in the hands, feet, or lower legs
  • Dexamethasone can interfere with sleep patterns, causing difficulty falling asleep or staying asleep
  • Some individuals may experience mood changes, irritability, or increased anxiety while taking dexamethasone
  • Dexamethasone can elevate blood sugar levels, which may be problematic for individuals with diabetes or prediabetes
  • Prolonged use of dexamethasone can weaken bones and increase the risk of osteoporosis or fractures
  • Dexamethasone can suppress the immune system, making individuals more susceptible to infections and delaying wound healing
  • Dexamethasone may cause stomach irritation, leading to symptoms such as indigestion, nausea, or stomach ulcers
  • Some individuals may experience skin reactions such as rash, itching, or acne while taking dexamethasone
  • Long-term use of dexamethasone can increase the risk of developing cataracts or glaucoma
  • Dexamethasone can disrupt hormone levels in the body, leading to menstrual irregularities or changes in libido
  • Prolonged use of dexamethasone can suppress the function of the adrenal glands, which may result in adrenal insufficiency when the medication is discontinued abruptly

Long-term use or high doses of dexamethasone can lead to serious side effects. It is important to promptly report any concerning symptoms to a healthcare provider.

Drug interactions of dexamethasone

Dexamethasone may interact with the following medications:

  • Taking dexamethasone with NSAIDs (Nonsteroidal Anti-inflammatory Drugs) such as ibuprofen or aspirin may increase the risk of gastrointestinal bleeding or ulcers
  • Dexamethasone can reduce the effectiveness of medicines to treat heart and blood problems, such as warfarin, high blood pressure medicine and water tablets (diuretics)
  • Dexamethasone may raise blood glucose levels, potentially counteracting the effects of antidiabetic medications. Dose adjustments may be necessary
  • Dexamethasone can weaken the immune system, potentially reducing the effectiveness of vaccines. It is advisable to consult with your healthcare provider before receiving any vaccinations
  • Dexamethasone may reduce the efficacy of certain antifungal medications like ketoconazole or itraconazole. Dose adjustments may be needed. You should not use dexamethasone if you have a fungal infection anywhere in your body
  • Dexamethasone can decrease the effectiveness of anticonvulsant medications like phenytoin or carbamazepine. Frequent monitoring and dosage adjustments may be required
  • Dexamethasone can interact with certain antibiotics, such as rifampin, erythromycin, and clarithromycin. These antibiotics can increase the metabolism of dexamethasone, leading to reduced effectiveness. Your healthcare provider may need to adjust the dosage of dexamethasone or switch to a different antibiotic
  • Dexamethasone can decrease the effectiveness of estrogen-containing medications, such as oral contraceptives or hormone replacement therapy. It is important to discuss alternative contraception methods with your healthcare provider if you are taking dexamethasone
  • Dexamethasone can increase the loss of potassium from the body. When combined with medications that also cause potassium loss, such as diuretics or certain asthma medications, it can lead to dangerously low potassium levels. Regular monitoring of potassium levels may be required
  • Dexamethasone can weaken the immune system, which may reduce the effectiveness of live vaccines. It is recommended to consult with your healthcare provider before receiving any live vaccines
  • Dexamethasone can interact with other medications that affect the immune system, such as immunosuppressants or immunomodulatory drugs. These interactions can lead to decreased effectiveness of both medications or increased risk of side effects. Close monitoring and dosage adjustments may be necessary when using dexamethasone with other immune-modulating medications

Similar drugs to dexamethasone

Other corticosteroid medications, such as prednisone and hydrocortisone, may be used as alternatives to dexamethasone for the treatment of inflammatory and immune-related conditions.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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