Desogestrel Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Desogestrel Ethinyl Estradiol & Ethinyl Estradiol
    Generic for Mircette, Volnea
    28 blister pack of tabletss $8.54 USD
    Save $22.80
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Do you need a prescription for desogestrel?

Yes, desogestrel is only available with a valid physician Rx.

How much is desogestrel without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase desogestrel, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for desogestrel in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a desogestrel savings card?

Yes. Save up to 90% on your desogestrel with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a desogestrel coupon provider in the US?

No. Now Patient does not provide desogestrel coupons or FREE desogestrel samples.

Do you accept commercial, Medicare or Medicaid coverage for desogestrel in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much desogestrel?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using desogestrel. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much desogestrel. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of desogestrel and manufacturer

Desogestrel is available in the US under the brand name Apri, which is manufactured by Teva Pharmaceuticals.

UK brand name of desogestrel and manufacturer

Desogestrel is available in the UK under various brand names, including Cerazette and desogestrel, which different pharmaceutical companies manufacture.

Prescription requirement for desogestrel

Desogestrel is a prescription medication in both the US and the UK. It is not available over the counter and requires a prescription from a healthcare provider.

FDA approval of desogestrel

Desogestrel has received FDA approval as an oral contraceptive, also known as a birth control pill.

Is desogestrel available in the UK on NHS?

Desogestrel is available on the NHS in the UK. It can be prescribed by healthcare providers as a contraceptive option.

Mechanism of action

Desogestrel is a progestogen-only pill. It contains synthetic progestin, which means it acts similarly to the hormone progesterone in the body. It works by preventing ovulation, thickening the cervical mucus to inhibit sperm penetration, and altering the uterine lining to make it less receptive to implantation.

Uses of desogestrel

Desogestrel is primarily used as an oral contraceptive to prevent pregnancy. It is a highly effective method when taken correctly. Desogestrel, commonly known as the mini-pill, is a type of birth control pill that contains only one hormone, progestin. This sets it apart from combined oral contraceptives which contain both estrogen and progestin.
Other Medical Uses
Desogestrel has several potential uses beyond birth control. It may be prescribed to regulate menstrual cycles, reduce menstrual pain, or treat conditions such as endometriosis. Desogestrel also shows potential as a hormone replacement therapy (HRT) for women going through menopause. It can help manage the symptoms of hot flashes, mood swings, and vaginal dryness that often accompany this stage of life. Additionally, desogestrel has been found to be an effective tool in managing polycystic ovary syndrome (PCOS), helping to regulate menstrual cycles and alleviate associated symptoms such as acne and excess hair growth. Furthermore, ongoing research is exploring off-label uses of desogestrel for conditions like acne treatment and endometriosis.

Dosage of desogestrel

The dosage of desogestrel will depend on the specific brand and formulation prescribed. It is important to follow the dosage instructions provided by your healthcare provider. Generally, desogestrel is taken orally once daily.

Precautions and warnings for desogestrel

  • Desogestrel should not be used in individuals who have a known allergy to the medication or any of its components
  • Before using this medication, tell your doctor or pharmacist if you are allergic to any estrogens (such as ethinyl estradiol, mestranol) or any progestins (such as norethindrone, desogestrel); or if you have any other allergies
  • Desogestrel usage may increase the risk of blood clot formation, which can be potentially dangerous and lead to serious health complications. It is crucial for patients to closely monitor any symptoms such as swelling or pain in the legs, shortness of breath, or chest pain and immediately seek medical attention if they occur
  • High blood pressure, diabetes, and obesity cause an increased risk of stroke and heart attack. These underlying conditions create a higher likelihood of developing cardiovascular complications when using desogestrel. It is crucial for patients to prioritize managing these health concerns to minimize potential risks
  • It is important to inform your healthcare provider about any existing medical conditions, especially if you have a history of blood clots, heart disease, liver disease (including tumours), breast cancer, gallbladder problems, thyroid problems, or unexplained vaginal bleeding
  • Using this medicine may increase your risk of breast cancer or cervical cancer. Talk with your doctor about this risk
  • Desogestrel does not protect against sexually transmitted infections (STIs). Additional barrier methods should be used for STI prevention
  • The use of desogestrel during pregnancy should be avoided, as it is intended for contraceptive purposes
  • Breastfeeding individuals should consult with their healthcare provider regarding the use of desogestrel, as it may affect milk production. This medicine passes into breast milk. Ask your doctor before breastfeeding

Side effects of desogestrel

In clinical trials common side effects of desogestrel may include menstrual irregularities, changes in menstrual bleeding patterns, breast tenderness/enlargement, weight gain, nausea, mood changes, contact lens discomfort and headache. Serious side effects are rare but may include blood clots, high blood pressure, and liver problems.

Serious side effects of desogestrel

  • Desogestrel may increase the risk of developing blood clots, which can lead to serious complications such as deep vein thrombosis or pulmonary embolism
  • Some individuals may experience severe allergic reactions to desogestrel, including rash, itching, swelling, dizziness, and difficulty breathing
  • In rare cases, desogestrel has been associated with depression or mood changes. It is important to monitor your mental health while taking this medication

Note that these are not all the possible adverse effects of desogestrel. It is essential to consult your healthcare provider for a complete list and discuss any concerns you may have before starting this medication.

Drug interactions

Antibiotics like rifampin, anticonvulsants like carbamazepine, and the herbal supplement St. John’s Wort can potentially interact with desogestrel, leading to decreased effectiveness of hormonal contraceptives. It is important to inform your healthcare provider if you are taking any of these medications or supplements while using desogestrel.

  • Certain antibiotics, like rifampicin and rifabutin, may reduce the effectiveness of desogestrel. It is advisable to use an alternative method of contraception while taking these antibiotics and for a week after completing the course
  • St. John’s Wort can increase the metabolism of desogestrel, potentially reducing its effectiveness. It is important to discuss the use of St. John’s Wort with your healthcare provider if you are taking desogestrel
  • Some antiepileptic drugs (AEDs) such as phenytoin, carbamazepine, and topiramate, can decrease the effectiveness of desogestrel. This may increase the risk of unintended pregnancy. If you are taking AEDs, your healthcare provider may recommend using an additional or alternative form of contraception
  • Women who are being treated for high cholesterol (high lipid levels) should be followed closely if they elect to use oral contraceptives. Some progestogens may increase concentrations of low-density lipoproteins and may render the control of hyperlipidemias more difficult
  • Some antiviral medications, including ritonavir and nevirapine, can affect the metabolism of desogestrel, potentially reducing its effectiveness. Your healthcare provider may need to adjust your treatment plan or recommend additional contraception methods
  • If you do become pregnant while you’re using desogestrel, there may be a small risk of an ectopic pregnancy



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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