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Desogestrel is available as an oral tablet that contains Desogestrel/ethinyl estradiol and ethinyl estradiol in a strength of 0.15 mg/0.02 mg/0.01 mg.

Desogestrel is a combined contraceptive that is used to prevent pregnancy.

Desogestrel is a combined contraceptive that contains two hormones: ethinyl estradiol (an estrogen) and Desogestrel (a progestin). Both hormones work together to prevent pregnancy by suppressing ovulation (release of an egg from the ovary), changing cervical mucus to block sperm movement, and aking it difficult for the fertilized egg to implant by changing the lining in the uterus.

Desogestrel comes in a 28-day pack. There are 26 active tablets and they contain different dosages of Desogestrel and ethinyl estradiol. The typical dose is 1 tablet by mouth at the same time every day. Tablets must be taken in the exact order of the blister pack.

Desogestrel is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:

• Thrombophlebitis or thromboembolic disorders
• A past history of deep vein thrombophlebitis or thromboembolic disorders
• Cerebral vascular or coronary artery disease
• Known or suspected carcinoma of the breast
• Carcinoma of the endometrium or other known or suspected estrogen-dependent neoplasia
• Undiagnosed abnormal genital bleeding
• Cholestatic jaundice of pregnancy or jaundice with prior pill use
• Hepatic adenomas or carcinomas
• Known or suspected pregnancy

Common side effects of Desogestrel:

• Nausea
• Vomiting
• Stomach cramps
• Bloating
• Spotting
• Breast tenderness
• Weight changes (up or down)
• Headache
• Raised blood pressure
• Depression

Serious side effects are rare with Desogestrel. Contact your healthcare provider immediately if you experience any of the following.

• Heart attack: chest pain, stomach discomfort, sweating, nausea, dizziness
• Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
• Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
• Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart

The following medications may interact with Desogestrel:

• Reduced efficacy and increased incidence of breakthrough bleeding and menstrual irregularities have been associated with concomitant use of rifampin. A similar association, though less marked, has been suggested with barbiturates, phenylbutazone, phenytoin sodium, carbamazepine and possibly with griseofulvin, ampicillin, and tetracyclines
• Combined hormonal contraceptives have been shown to significantly decrease plasma concentrations of lamotrigine. This may reduce seizure control; therefore, dosage adjustments of lamotrigine may be necessary.
• Consult the labeling of the concurrently-used drug to obtain further information about interactions with hormonal contraceptives or the potential for enzyme alterations

Various FDA-approved generic manufacturers

Desogestrel is contraindicated during pregnancy as it may cause fetal harm when administered to pregnant women.

• Mircette
• Volnea