Key facts about Clobetasol
What dosages is Clobetasol available in?
Clobetasol is available as a 0.05% topical cream, gel, solution, spray, lotion, foam, and ointment.
What is Clobetasol used for?
Clobetasol is a corticosteroid that is used to treat:
- Treatment of skin rashes and itchy skin – all topical forms except shampoo
- Treatment of moderate to severe scalp psoriasis – foam and shampoo only
- Treatment of plaque psoriasis not on the scalp – all topical forms except shampoo
How does Clobetasol work?
Clobetasol is a topical corticosteroid. When it’s used on the skin, it has three actions:
- It lowers the amount of inflammatory chemicals that cause redness, itching, and swelling. This helps to lower skin inflammation
- It can also slow down new skin cells from being made, which can help lower the amount of patches or scales in some skin problems (e.g., psoriasis)
- Finally, it lessens the immune response of your body, which can help with certain skin problems that are caused by a sensitive immune system (e.g., eczema)
How do I take Clobetasol?
Clobetasol is typically applied as a thin layer to the affected area(s) twice daily.
Is it safe for me to take Clobetasol?
Clobetasol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Clobetasol Common Side Effects
Common side effects of Clobetasol:
- Burning
- Stinging
- Skin irritation
- Itching
- Dry skin
- Rash
- Thinning skin
Clobetasol Serious Side Effects
Serious side effects are rare with Clobetasol.
Effects of other drugs, drug classes and over-the-counter products on Clobetasol
- There are no major drug interactions listed for Clobetasol. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes Clobetasol?
Various FDA-approved generic manufacturers
Is Clobetasol safe in pregnancy?
There are no adequate and well-controlled studies in pregnant women. Therefore, Clobetasol should be used during
pregnancy only if the potential benefit justifies the potential risk to the fetus.













