BupropionPrices, Coupons & Savings
Mail Order Pharmacy
- MedicationYou saveUS ONLY
- Bupropion HClGeneric for WellbutrinRx75mg30 tablets $4.8 USD30 tablets $4.8 USD - 0.16 USD/tabletSave $17.10
- Bupropion HClGeneric for WellbutrinRx100mg60 tablets $5.7 USD60 tablets $5.7 USD - 0.1 USD/tabletSave $38.10
- Bupropion SRGeneric for Wellbutrin SRRx150mg30 sustained release tablets $4.2 USD30 sustained release tablets $4.2 USD - 0.14 USD/sustained release tabletSave $6.30
- Bupropion SRGeneric for Wellbutrin SRRx200mg30 sustained release tablets $5.4 USD30 sustained release tablets $5.4 USD - 0.18 USD/sustained release tabletSave $5.10
- Bupropion SRGeneric for Wellbutrin SRRx100mg30 sustained release tablets $5.1 USD30 sustained release tablets $5.1 USD - 0.17 USD/sustained release tabletSave $5.40
- Bupropion XLGeneric for Wellbutrin XLRx150mg30 extended release tablets $4.8 USD30 extended release tablets $4.8 USD - 0.16 USD/extended release tabletSave $62.70
- Bupropion XLGeneric for Wellbutrin XLRx300mg60 extended release tablets $5.7 USD60 extended release tablets $5.7 USD - 0.1 USD/extended release tabletSave $129.30

Do you need a prescription for bupropion?
Yes, bupropion is only available with a valid physician Rx.
How much is bupropion without Insurance in the US?
Our website gives two competitive savings options to US customers who wish to purchase bupropion, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.
What will my out-of-pocket cost be for bupropion in the US?
There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.
Is Now Patient a bupropion savings card?
Yes. Save up to 90% on your bupropion with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.
Can you handle Rx transfers for home delivery in the US?
Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.
Is Now Patient a bupropion coupon provider in the US?
No. Now Patient does not provide bupropion coupons or FREE bupropion samples.
Do you accept commercial, Medicare or Medicaid coverage for bupropion in the US?
No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.
Does Now Patient work with Medicare?
Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.
Does Now Patient work with Commercial Insurance?
Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.
What should you do if you use too much bupropion?
Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using bupropion. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much bupropion. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.
If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.
What should I do if I miss my dose?
There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.
Click here to find out what to do if you forgot to take your medication
What is generic bupropion?
Generic bupropion refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.
FDA approval of bupropion
Bupropion is approved by the U.S. Food and Drug Administration (FDA) for the treatment of major depressive disorder and seasonal affective disorder. It is also approved as an aid to smoking cessation.
Active ingredient of bupropion
The active ingredient of bupropion is bupropion hydrochloride.
US brand name of bupropion and manufacturer
Bupropion is available in the US under various brand names, including Wellbutrin. It is manufactured by various pharmaceutical companies.
UK brand name of bupropion and manufacturer
In the UK, bupropion was marketed under the brand name Zyban (smoking cessation), until it was withdrawn due to possible nitrosamine impurities, in December 2022.
Prescription requirement for bupropion
A prescription (Rx) is required for bupropion in both the US.
Availability of bupropion in the UK with NHS prescription
Bupropion is not available in the UK.
Conditions treated by bupropion
Bupropion is primarily used for the treatment of major depressive disorder, seasonal affective disorder (SAD), and as an aid to smoking cessation. It is classified as an atypical antidepressant that affects certain neurotransmitters in the brain.
How does bupropion work?
The exact mechanism of action of bupropion is not fully understood. It is believed to work by inhibiting the reuptake of dopamine and norepinephrine in the brain, which helps to restore the balance of these neurotransmitters. This is thought to contribute to its antidepressant and smoking cessation effects.
Forms of bupropion available
Bupropion is available in the form of oral tablets and extended-release tablets.
Dosage of bupropion
The dosage of bupropion may vary depending on the specific condition being treated and the individual’s response to the medication. It is important to follow the recommended dosage instructions provided by the healthcare provider.
Directions for bupropion use
Bupropion should be taken exactly as directed by the healthcare provider. The medication is usually taken once or twice daily, with or without food. It is important to take bupropion consistently and continue the prescribed treatment course.
Warnings and precautions for bupropion
- Bupropion may increase the risk of suicidal thoughts and behaviors, especially in children, adolescents, and young adults. Close monitoring is necessary during treatment.
- It may interact with certain medications, including monoamine oxidase inhibitors (MAOIs) and selective serotonin reuptake inhibitors (SSRIs). Inform the healthcare provider about all medications being taken.
Use of bupropion during pregnancy
The use of bupropion during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.
Use of bupropion while breastfeeding
Bupropion may pass into breast milk, but the amount is usually low. It is recommended to consult a healthcare provider before using Bupropion while breastfeeding.
Possible side effects of bupropion
Common side effects of bupropion may include dry mouth, insomnia, headache, nausea, and agitation. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider.
Similar drugs to bupropion
Other antidepressant medications used for the treatment of depression and smoking cessation include selective serotonin reuptake inhibitors (SSRIs) such as sertraline and fluoxetine.
Sources:
- FDA Prescribing Information for Bupropion
- MHRA GOV.UK
- WebMD – Bupropion
- Drugs.com – Bupropion
- NHS UK
Disclaimer
Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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