AzathioprinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Azathioprine
    Generic for Imuran
    30 tablets $8.1 USD
    Save $36.90
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Do you need a prescription for azathioprine?

Yes, azathioprine is only available with a valid physician Rx.

How much is azathioprine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase azathioprine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for azathioprine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a azathioprine savings card?

Yes. Save up to 90% on your azathioprine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a azathioprine coupon provider in the US?

No. Now Patient does not provide azathioprine coupons or FREE azathioprine samples.

Do you accept commercial, Medicare or Medicaid coverage for azathioprine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much azathioprine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using azathioprine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much azathioprine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

FDA approval of azathioprine

Azathioprine is approved by the U.S. Food and Drug Administration (FDA) for certain medical conditions, including the prevention of organ rejection in kidney transplantation and the treatment of rheumatoid arthritis.

US brand name of azathioprine and manufacturer

Azathioprine is available under the brand name Imuran, which is manufactured by GlaxoSmithKline.

UK brand name of azathioprine and manufacturer

In the UK, azathioprine is available under various brand names, including Imuran and azathioprine. Different pharmaceutical companies manufacture these brands.

Availability of azathioprine

Azathioprine is available by prescription only.

NHS prescription (UK)

Azathioprine is available in the UK with an NHS prescription.

Mechanism of action

Azathioprine works by suppressing the immune system. It does this by inhibiting the production of DNA and RNA in rapidly dividing cells, such as those found in the bone marrow and blood cells. When taken orally, azathioprine is converted into active metabolites within the body. These metabolites interfere with certain enzymes that are essential for DNA synthesis and cell proliferation. By disrupting these processes, azathioprine reduces the activity of immune cells involved in inflammatory responses. The metabolites produced from azathioprine play a crucial role in its immunosuppressive effects. They selectively target rapidly dividing immune cells and inhibit their function. This helps to prevent excessive inflammation and suppresses an overactive immune response commonly seen in autoimmune diseases like rheumatoid arthritis or inflammatory bowel disease.

Medical conditions treated with azathioprine

Azathioprine is a medication commonly used for treating various medical conditions. It is particularly effective in treating autoimmune diseases and preventing transplant rejection. By suppressing the immune system and inhibiting the production of certain white blood cells in bone marrow, azathioprine helps manage conditions such as rheumatoid arthritis, lupus nephritis, and systemic vasculitis. In addition to its role in autoimmune diseases and organ transplantation, azathioprine also serves as an adjunctive therapy for inflammatory bowel disease (IBD). This includes conditions like Crohn’s disease and ulcerative colitis. By reducing inflammation in the intestines and regulating immune responses, azathioprine can help control symptoms of IBD when other treatments have been insufficient or intolerable.

Is it safe with breastfeeding?

It is not recommended to use azathioprine while breastfeeding as the drug is excreted at low levels in breast milk. It is important to consult with your healthcare provider for appropriate alternatives or considerations.

Is it safe to take if I am pregnant or planning on becoming pregnant?

If you are pregnant, planning to become pregnant or suspect you may be pregnant, it is important to discuss the use of azathioprine with your healthcare provider and receive medical advice. They can evaluate the potential risks and benefits to determine the best course of action for your specific situation.

Precautions and warnings for azathioprine

  • While you are taking this medicine, you might be asked to have regular blood tests (blood cell counts and liver function tests) to evaluate the medicine’s effectiveness. Regularly monitor blood cell counts when taking azathioprine alongside allopurinol
  • Close monitoring of blood pressure and white blood cell counts is important when using azathioprine with ACE inhibitors
  • When taking warfarin alongside azathioprine, there is an increased risk of bleeding complications due to enhanced anticoagulant effects. Close monitoring and adjustment of dosage may be necessary to prevent adverse outcomes
  • For people with TPMT (thiopurine methyltransferase) deficiency dosage of azathioprine may need to be lowered if tests show that you have TPMT deficiency. TPMT is an enzyme in your body that breaks down azathioprine. When you don’t have enough TPMT, you’re at increased risk of side effects and blood disorders from azathioprine
  • Azathioprine may increase your risk of developing certain types of cancer, especially skin cancer and lymphoma. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors
  • Azathioprine is very similar to mercaptopurine. Do not use medications containing mercaptopurine while using azathioprine
  • It is important to inform a healthcare professional about all the prescription medications including over-the-counter drugs and supplements you are taking to avoid potential drug interactions

Drug interactions 

Azathioprine may interact with certain medications, including allopurinol, ACE inhibitors, and angiotensin receptor blockers. It is important to inform your healthcare provider about all the medications you are taking to avoid potential interactions.

Side effects of azathioprine

Common adverse effects of azathioprine may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Hair loss

Serious side effects of azathioprine may include:

  • Bone marrow suppression
  • Increased risk of infection

It may also cause liver toxicity, potentially leading to liver damage or failure. In rare cases, azathioprine can result in blood disorders such as anemia or low blood cell count, which can compromise overall health.

Dosage of azathioprine

The dosage of azathioprine may vary depending on the individual patient, the condition being treated, and other factors. It is important to follow the instructions provided by your healthcare provider. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. Store this medicine at room temperature.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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