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anitihemophilic factor (recombinant) is available as a single-dose vial containing 250 IU, 500 IU, 1000 IU, 2000 IU, or 3000 IU.

anitihemophilic factor (recombinant) is a recombinant,human DNA sequence derived, full length Factor VIII concentrate indicated for use in adults and children with hemophilia A (congenital Factor VIII
deficiency) for:

• On-demand treatment and control of bleeding episodes
• Perioperative management of bleeding
• Routine prophylaxis to reduce the frequency of bleeding episodes

anitihemophilic factor (recombinant) is a clotting factor replacement for people who are missing special blood-clotting proteins called factor VIII (FVIII) due to hemophilia A. By replacing the missing clotting factor (FVIII, or antihemophilic factor) in people who naturally don’t have it, bleeding episodes can be reduced or treated.

anitihemophilic factor (recombinant) is typically dosed as follows:

• Adults and adolescents: 20-40 IU/kg 2 or 3 times per week
• Children ≤12 years old: 25-50 IU/kg 2 times per week, 3 times per week or every other day

anitihemophilic factor (recombinant) is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a history of hypersensitivity reactions to the active substance, mouse or hamster protein, or other constituents of the product.

Common side effects of anitihemophilic factor (recombinant):

• Fever
• Headache
• Rash

Serious side effects are rare with anitihemophilic factor (recombinant). Contact your healthcare provider immediately if you experience any of the following.

• Hypersensitivity reactions, including anaphylaxis, are possible. Should symptoms occur, discontinue treatment with anitihemophilic factor (recombinant) and administer appropriate treatment

• There are no major drug interactions listed for anitihemophilic factor (recombinant). However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking

Various FDA-approved generic manufacturers

There are no data with anitihemophilic factor (recombinant) use in pregnant women to inform on drug-associated risk. Animal reproduction studies have not been conducted using anitihemophilic factor (recombinant). It is not known whether anitihemophilic factor (recombinant) can cause fetal harm when
administered to a pregnant woman or can affect reproduction capacity.

• Kogenate FS
• Kovaltry