Treat Sinusitis With Fluticasone Furoate
Learn how Fluticasone Furoate treats Sinusitis, how to use it safely, who it's suitable for, and what results to expect. When clinically appropriate, our trained clinicians can assess your symptoms online and provide treatment without needing a GP appointment.


MEDICAL INFORMATION
Fluticasone Furoate Key Facts
Who Manufactures Fluticasone Furoate?
Fluticasone Furoate is manufactured by various MHRA approved generic manufacturers.
What Form is Fluticasone Furoate available in?
Fluticasone Furoate is available as Fluticasone Furoate 27.5 micrograms/ dose nasal spray.
How do I store Fluticasone Furoate?
Store Fluticasone Furoate nasal spray at room temperature, away from excess moisture and heat. Store upright, always with the cap on.
What is Fluticasone Furoate used for?
Fluticasone Furoate nasal spray is used for the treatment of acute sinusitis (rhinosinusitis) under the NHS England commissioned Pharmacy First service.
How does Fluticasone Furoate work?
Fluticasone Furoate is a corticosteroid that works as an anti-inflammatory agent. Fluticasone Furoate helps to reduce swelling and irritation in the nose by preventing the release of chemicals that cause the allergic response.
When will I feel better and what should I do if I do not get better?
You should begin to feel better within a few days of using the Fluticasone Furoate nasal spray. If your symptoms do not improve or get worse, call your doctor.
Can I drink alcohol while taking Fluticasone Furoate?
Yes, you can drink alcohol while using the Fluticasone Furoate nasal spray.
Do I need to take Fluticasone Furoate with food?
You can use Fluticasone Furoate with or without food.
Who can and cannot take Fluticasone Furoate?
You may use the Fluticasone Furoate nasal spray if you meet the inclusion criteria for sinusitis for the Pharmacy First service, but may not use the Fluticasone Furoate nasal spray if you meet the exclusion criteria for sinusitis for the Pharmacy First service.
How often do I need to take Fluticasone Furoate?
Adults and children aged 12-17 should use two actuations (27.5 micrograms/actuation) in each nostril twice daily (total dose 110 micrograms twice daily) for 14 days.
What are the side effects of Fluticasone Furoate?
Side effects of Fluticasone Furoate unclude epistaxis, headaches, throat irritation, nasal ulceration, dyspnoea, altered smell or taste.
Are there any Interactions of Fluticasone Furoate with other drugs?
Interactions do not generally apply to corticosteroids used for topical action (including inhalation).
Other important information about Fluticasone Furoate
Use the Fluticasone Furoate nasal spray at regular intervals and finish the course even if symptoms improve. Seek medical advice in the event of an adverse reaction or if any other new symptoms develop.
Does Fluticasone Furoate interfere with conception and contraception?
Fluticasone Furoate does not affect fertility in men or women and does not stop any type of contraception from working.
Can I use Fluticasone Furoate when breast feeding?
It is not known if Fluticasone Furoate is excreted in human breast milk when administered as a nasal spray. Administration of Fluticasone Furoate to women who are breast-feeding should only be considered if the expected benefit is greater than any risk to the child.
Can I use Fluticasone Furoate if I am pregnant or planning to become pregnant?
Fluticasone Furoate nasal spray should not be used in pregnancy unless the potential benefit justifies any potential risk to the mother or foetus. Fluticasone Furoate nasal spray is excluded from the Pharmacy First service if you are pregnant or suspect you are pregnant and are under the age of 16.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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FAQs
Answers to Popular Questions About How Fluticasone Furoate Treats Sinusitis
What is Fluticasone Furoate nasal spray and how is it used for acute sinusitis?
Fluticasone furoate is a potent intranasal corticosteroid available as a nasal spray (branded as Avamys). It is used to reduce inflammation, congestion, and swelling in the nasal passages and sinuses during acute sinusitis. NICE recommends intranasal corticosteroids as a treatment option for acute sinusitis, either alone or alongside antibiotics. Through the NHS Pharmacy First service, pharmacists can supply fluticasone furoate nasal spray for sinusitis without a GP appointment.
How do I use Fluticasone Furoate nasal spray for sinusitis?
Adults and children 12 years and over: 2 sprays in each nostril once daily. Some prescribers may recommend twice daily during acute episodes. Shake the bottle gently before use, blow your nose first, and aim the spray towards the outer wall of the nostril (away from the nasal septum). Breathe in gently through the nose. Continue for the duration advised by your pharmacist — typically 7–14 days for acute sinusitis. Do not sniff hard after spraying.
How does Fluticasone Furoate help with sinusitis?
Fluticasone furoate reduces inflammation in the nasal and sinus lining, which helps reduce swelling, congestion, and mucus production. By reducing swelling around the sinus openings (ostia), it improves sinus drainage and ventilation, helping the sinusitis resolve. Intranasal corticosteroids can relieve symptoms of facial pain/pressure, nasal congestion, and post-nasal drip. They may also reduce the need for antibiotics in mild to moderate sinusitis.
Can I get Fluticasone Furoate through Pharmacy First?
Yes, pharmacists can supply fluticasone furoate nasal spray through the NHS Pharmacy First service for acute sinusitis. The pharmacist will assess your symptoms and may recommend this spray alone for milder cases or alongside antibiotics for more severe bacterial sinusitis. This is a free NHS service.
What are the side effects of Fluticasone Furoate nasal spray?
Common side effects include nosebleeds (epistaxis — the most common side effect), nasal irritation or dryness, and headache. To reduce nosebleed risk, aim the spray away from the nasal septum (the centre wall of the nose). Rarely, nasal septum perforation can occur with prolonged use. Systemic corticosteroid effects are very rare with nasal sprays at recommended doses.
Can I use Fluticasone Furoate alongside a decongestant spray?
Yes, you can use a short course (up to 7 days) of a nasal decongestant spray (e.g., xylometazoline/oxymetazoline) alongside fluticasone furoate. Use the decongestant first to open the nasal passages, wait 5–10 minutes, then use the fluticasone spray to allow better penetration. Do not use decongestant sprays for more than 7 consecutive days, as rebound congestion (rhinitis medicamentosa) can develop.
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