TRAZIMERA
Used for Cancer
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Manufactured by Pfizer
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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TRAZIMERA Uses, Side Effects, Interactions, Warnings & Dosing
What is TRAZIMERA?
TRAZIMERA is the brand name for trastuzumab-qyyp and is available as an IV injection.
What dosages is TRAZIMERA available in?
TRAZIMERA is available as a 150 mg or 420 mg IV injection.
What is TRAZIMERA used for?
TRAZIMERA is a monoclonal antibody that is used to treat:
HER2-positive, breast cancers – IV and SQ injections
HER2-positive, metastatic stomach cancer – IV injection only
How does TRAZIMERA work?
TRAZIMERA s a monoclonal antibody that acts as a human epidermal growth factor receptor 2 (HER2) inhibitor. It blocks a specific protein in the body that’s important for cell growth called HER2. HER2 is found on both normal and cancer cells. Cancer cells usually have more HER2 proteins than normal cells. This can cause cancer cells to grow more quickly than normal cells. When HER2 is blocked by TRAZIMERA, cancer cells can’t grow and spread as well.
How do I take TRAZIMERA?
TRAZIMERA is given by a healthcare provider as an injection into a vein (IV).
When given IV, the dose depends on your body weight. Your healthcare provider will determine the appropriate dose for you each time you receive the medication.
HER2-positive, breast cancers
IV injection: The typical dose is 4 mg/kg of bodyweight IV for the first injection, and then 2 mg/kg given once a week. It can also be given as 8 mg/kg for the first injection, and then 6 mg/kg every 3 weeks thereafter.
HER2-positive, metastatic stomach cancer: The typical dose is 8 mg/kg IV for the first injection, and then 6 mg/kg every 3 weeks thereafter.
Is it safe for me to take TRAZIMERA?
TRAZIMERA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
TRAZIMERA Common Side Effects
Common side effects of TRAZIMERA:
- Body and joint pain
- Weakness
- Fever
- Nausea
- Chills
- Headache
- Cough
- Diarrhea
- Vomiting
- Infection
TRAZIMERA Serious Side Effects
Serious side effects are rare with TRAZIMERA. Contact your healthcare provider immediately if you experience any of the following.
Heart problems: chest pain, racing heartbeat, shortness of breath that usually worsens with activity or while lying flat, swelling of your legs or feet, sudden weight gain, fatigue
Serious infusion reactions: trouble breathing, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting
Lung problems: shortness of breath, trouble breathing
Serious infections (when receiving in combination with chemotherapy): repeated fevers, chills, sweating, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
Effects of other drugs, drug classes and over-the-counter products on TRAZIMERA
The following medications may interact with TRAZIMERA:
- Patients who receive anthracycline after stopping trastuzumab products may be at increased risk of cardiac dysfunction because of trastuzumab’s long washout period based on population PK analysis. If possible, physicians should avoid anthracycline-based therapy for up to 7 months after stopping trastuzumab products. If anthracyclines are used, the patient’s cardiac function should be monitored carefully.
Who makes TRAZIMERA?
Pfizer
Is TRAZIMERA safe in pregnancy?
TRAZIMERA can cause fetal harm when administered to a pregnant woman. If you can become pregnant, you should use effective contraception during treatment with TRAZIMERA and for 7 months following the last dose of TRAZIMERA. Contact your doctor immediately if you become pregnant while taking this medication.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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