Tegsedi Prices, Discounts & Coupons
NowPatient can significantly lower the cost* of your prescription medication by providing free access to drug coupons, savings cards, patient assistance programs and other out of pocket discount programs. Whether you’re insured, uninsured, or underinsured, we empower you with transparency and cost-saving tools to make your Tegsedi more affordable.
Manufactured by Akcea Therapeutics
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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Lower the Cost of Your Tegsedi Prescription
Rx Advantage Card
Our savings card can be used in over 65,000 pharmacies and could save you up to 90% on the cost of your medication. Suitable for insured, underinsured and uninsured individuals. This is not health insurance and cannot be used in conjunction with insurance.
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Canadian Online Pharmacy
Our trusted licensed Canadian pharmacy partner, Prescription Help, is on hand to offer great savings on the cost of your medications.
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Drug Coupons
For those who are commercially insured, drug manufacturer coupons can help reduce your out-of-pocket costs. Eligible for commercially insured only.
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Patient Assistance Programs
Patient assistance programs (PAPs) are sponsored by pharmaceutical companies and can mean you can obtain your medications at no cost to you. Suitable for insured, underinsured and uninsured individuals who are financially constrained.
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MEDICAL INFORMATION
Tegsedi Key Facts
What is Tegsedi?
Tegsedi is the brand name for inotersen and is available as a subcutaneous injection.
What dosages is Tegsedi available in?
Tegsedi is available as a 284 mg/1.5 mL single-dose prefilled syringe.
What is Tegsedi used for?
Tegsedi is a medication used to treat polyneuropathy from hereditary transthyretin-mediated amyloidosis (hATTR).
How does Tegsedi work?
Tegsedi is a transthyretin-directed antisense oligonucleotide. It works by preventing the creation of misshapened TTR proteins, which lowers the amount of amyloid that builds up.
How do I take Tegsedi?
The recommended dose of Tegsedi is 284 mg injected under the skin once weekly.
Is it safe for me to take Tegsedi?
Tegsedi is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Low platelet count
- History of glomerulonephritis (kidney damage) from Tegsedi
- History of a hypersensitivity reaction to Tegsedi
Tegsedi Common Side Effects
Common side effects of Tegsedi:
- Injection site reactions
- Nausea
- Headache
- Fatigue
- Low platelet count
- Fever
- Swelling in hands, feet, or ankles
- Chills
- Low red blood cells
- Vomiting
- Muscle pain
Tegsedi Serious Side Effects
Serious side effects are rare with Tegsedi. Contact your healthcare provider immediately if you experience any of the following:
- Low platelet count: unusual bleeding or bruising, bleeding that lasts for a long time, difficulty stopping bleeds, blood in vomit, urine, or stool, dizziness, lightheadedness
- Kidney damage: puffy face, dark or brown-colored urine, urinating less frequently, swelling of ankles, frequent urination at night, bubbly or foamy urine, lack of appetite
- Liver damage: yellowing of your skin or the whites of your eyes, fatigue, low appetite, nausea, vomiting, stomach discomfort
- Stroke: sudden trouble speaking, droopy face, sudden confusion, numbness or weakness in the face, arm, or leg
- Allergic reaction: chest pain, chills, flushing, joint or muscle pain, flu-like symptoms, difficulty swallowing, redness in the palms of your hands, jerking movements
Effects of other drugs, drug classes and over-the-counter products on Tegsedi
The following medications may interact with Tegsedi:
- Antiplatelet drugs (e.g., adenosine, clopidogrel, prasugrel, ticagrelor, or ticlopidine, aspirin, nonsteroidal anti-inflammatory drugs)
- Anticoagulants (e.g., heparin, warfarin)
- Drugs that may impair kidney function
Who makes Tegsedi?
Akcea Therapeutics
Is Tegsedi safe in pregnancy?
It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.
What is the generic name for Tegsedi?
Drug Savings Guide
A Practical Guide to Saving Money and Receiving Support With Prescription Drug Costs
How can NowPatient help me to lower the cost of my Tegsedi prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your Tegsedi prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient Tegsedi savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient Tegsedi savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for Tegsedi | Canadian Prescription Savings* for Tegsedi | Tegsedi Drug Coupon* | Tegsedi Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of Tegsedi?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for Tegsedi | Canadian Prescription Savings* for Tegsedi | Tegsedi Drug Coupon* | Tegsedi Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the Tegsedi savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the Tegsedi drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for Tegsedi, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the Tegsedi prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, Tegsedi is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed Tegsedi for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the Tegsedi prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the Tegsedi prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for Tegsedi
If you are having trouble paying for your Tegsedi medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for Tegsedi you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- Tegsedi is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers Tegsedi
- If Tegsedi is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for Tegsedi
If you are having trouble paying for your Tegsedi medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for Tegsedi you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers Tegsedi
- If Tegsedi is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for Tegsedi
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your Tegsedi treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for Tegsedi you will need to meet the following criteria:
- You must be currently insured and have coverage for Tegsedi
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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