spironolactone/hctz
Used for Hypertension
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Manufactured by various FDA-approved generic manufacturers.
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spironolactone/hctz Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is spironolactone/hctz available in?
spironolactone/HCTZ is available as a 25 mg/25 mg and 50 mg/50 mg tablet.
What is spironolactone/hctz used for?
spironolactone/HCTZ is a combination medicine used to treat hypertension or swelling due to liver damage (cirrhosis), nephrotic syndrome (a rare kidney condition), or congestive heart failure.
How does spironolactone/hctz work?
spironolactone/HCTZ contains spironolactone, which is a potassium-sparing diuretic (water pill) that works in your kidneys you urinate more without lowering the amount of potassium. This helps lower the amount of fluid in your blood vessels and other areas of your body. It also contains hydrochlorothiazide, which is a thiazide diuretic (water pill) that makes you urinate more. It works in your kidneys to remove extra water and certain electrolytes (like sodium and potassium), which helps lower your blood pressure and decrease swelling throughout your body.
How do I take spironolactone/hctz?
spironolactone/HCTZ can be taken as a single dose once a day or split into smaller doses and be taken twice a day.
Is it safe for me to take spironolactone/hctz?
spironolactone/HCTZ is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. spironolactone/HCTZ is contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison’s disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. spironolactone/HCTZ may also be contraindicated in acute or severe liver failure.
spironolactone/hctz Common Side Effects
Common side effects of spironolactone/HCTZ include:
- Enlargement of a man’s breasts
- Dizziness
- Low blood pressure
- Sensitivity to the sun
spironolactone/hctz Serious Side Effects
Serious side effects are rare with spironolactone/HCTZ. Contact your healthcare provider immediately if you experience any of the following.
- Stevens-Johnson Syndrome and toxic epidermal necrolysis (rare, but life-threatening skin disorders)
- High levels of potassium in the blood
- Kidney failure
- Severe allergic reactions
Effects of other drugs, drug classes and over-the-counter products on spironolactone/hctz
ACE inhibitors, Angiotensin II receptor antagonists, aldosterone blockers, potassium supplements, heparin, low molecular weight heparin, and other drugs known to cause hyperkalemia. Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. Nonsteroidal anti-inflammatory drugs (NSAIDs): In some patients, the administration of an NSAID can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing, and thiazide diuretics. Combination of NSAIDs, e.g., indomethacin, with potassium-sparing diuretics has been associated with severe hyperkalemia. Lithium: Lithium generally should not be given with diuretics. Diuretics: May reduce the renal clearance of lithium and add a high risk of lithium toxicity. Cholestyramine: Hyperkalemic metabolic acidosis has been reported with concomitant use.
Who makes spironolactone/hctz?
Various FDA-approved generic manufacturers
Is spironolactone/hctz safe in pregnancy?
It is not known if spironolactone/HCTZ will harm your unborn baby. If you become pregnant while receiving spironolactone/HCTZ, talk to your healthcare provider.
What to do if you missed your spironolactone/hctz dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Tips
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
What is the brand name for spironolactone and HCTZ?
Why is HCTZ and spironolactone given together?
What are the long term side effects of spironolactone?
What is the cost of spironolactone HCTZ?
Is spironolactone stronger than HCTZ?
What time of day should you take spironolactone?
Is spironolactone the same as Lasix?
Can spironolactone affect your eyes?
What is the new version of spironolactone?
What drugs does spironolactone interact with?
Is spironolactone a good diuretic?
Does spironolactone raise blood sugar?
Does spironolactone HCTZ cause weight gain?
Can spironolactone reduce belly fat?
Does spironolactone change a woman's body?
Does spironolactone make your face puffy?
Does HCTZ help you lose weight?
Does spironolactone affect sleep?
What organs does spironolactone affect?
How does spironolactone affect mood?
How common is weight gain with spironolactone?
Can you go in the sun on spironolactone?
What does spironolactone do for hair loss?
What are the common adverse effects of the combination diuretics spironolactone and hydrochlorothiazide?
Why give HCTZ and spironolactone together?
What is the most significant adverse effect of spironolactone?
What medications should not be taken with HCTZ?
Has anyone lost weight on spironolactone?
Does spironolactone cause kidney damage?
What is the major adverse effect of hydrochlorothiazide?
What unique effects does spironolactone have as a diuretic drug?
Does spironolactone affect the eyes?
Is spironolactone stronger than hydrochlorothiazide?
Does spironolactone cause hair loss?
What should you avoid while taking spironolactone?
What is bad about spironolactone?
Is spironolactone bad for your heart?
What organ does spironolactone affect?
Why can't you take spironolactone at night?
Do you gain weight on spironolactone?
What drugs interact with spironolactone?
Is spironolactone a high risk medication?
Is spironolactone toxic to the liver?
What happens if you drink alcohol while taking spironolactone?
What are the benefits of taking spironolactone?
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