Spironolactone-HCTZPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Spironolactone-HCTZ
    Generic for Aldactazide
    30 tablets $16.8 USD
    Save $16.20
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Do you need a prescription for spironolactone-hctz?

Yes, spironolactone-hctz is only available with a valid physician Rx.

How much is spironolactone-hctz without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase spironolactone-hctz, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for spironolactone-hctz in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a spironolactone-hctz savings card?

Yes. Save up to 90% on your spironolactone-hctz with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a spironolactone-hctz coupon provider in the US?

No. Now Patient does not provide spironolactone-hctz coupons or FREE spironolactone-hctz samples.

Do you accept commercial, Medicare or Medicaid coverage for spironolactone-hctz in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much spironolactone-hctz?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using spironolactone-hctz. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much spironolactone-hctz. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic spironolactone-HCTZ?

Generic spironolactone-HCTZ refers to the non-brand-name version of the medication. It contains the same active ingredients as the brand-name drug but is typically less expensive.

FDA approval of spironolactone-HCTZ

Spironolactone-HCTZ is approved by the U.S. Food and Drug Administration (FDA) for the treatment of high blood pressure and fluid retention (edema).

Active ingredients of spironolactone-HCTZ

Spironolactone-HCTZ is a combination medication that contains two active ingredients: spironolactone and hydrochlorothiazide.

US brand name of spironolactone-HCTZ and manufacturer

Spironolactone-HCTZ is available under various brand names in the US, including Aldactazide. These medications are manufactured by different pharmaceutical companies.

UK brand name of spironolactone-HCTZ and manufacturer

In the UK, spironolactone-HCTZ is available under various brand names, and the manufacturers may vary.

Prescription requirement for spironolactone-HCTZ

A prescription (Rx) is required for spironolactone-HCTZ in both the US and the UK.

Availability of spironolactone-HCTZ in the UK with NHS prescription

Spironolactone-HCTZ is available in the UK with an NHS prescription.

Conditions treated by spironolactone-HCTZ

Spironolactone-HCTZ is used to treat high blood pressure (hypertension) and edema (fluid retention) associated with certain conditions, such as congestive heart failure, liver cirrhosis, and kidney disorders.

How does spironolactone-HCTZ work?

Spironolactone-HCTZ combines two different types of medications: spironolactone, which is a potassium-sparing diuretic, and hydrochlorothiazide, which is a thiazide diuretic. Spironolactone works by blocking the effects of a hormone called aldosterone, reducing the retention of salt and water. Hydrochlorothiazide increases urine production, leading to the elimination of excess fluid from the body.

Forms of spironolactone-HCTZ available

Spironolactone-HCTZ is available in the form of oral tablets.

Dosage of spironolactone-HCTZ

The dosage of spironolactone-HCTZ may vary depending on the specific condition being treated, the severity of the condition, and individual patient factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider.

Directions for spironolactone-HCTZ Use

Spironolactone-HCTZ should be taken exactly as directed by the healthcare provider. The tablets should be swallowed whole with a glass of water. It is usually taken once daily, with or without food.

Warnings and precautions for spironolactone-HCTZ

  • Spironolactone-HCTZ may cause potassium levels in the body to become too high. Regular monitoring of potassium levels is important, especially in patients with kidney problems or those taking other medications that can affect potassium levels
  • Tell your doctor if you have Addison’s disease (an adrenal gland disorder), electrolyte imbalances such as high levels of potassium or low levels of calcium, sodium or magnesium, in your blood, kidney disease, liver disease, or heart disease
  • It may interact with certain medications, including other diuretics, blood pressure medications, and nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Spironolactone-HCTZ is not recommended if you have an allergy to spironolactone, hydrochlorothiazide, or sulfa medication

Use of spironolactone-HCTZ during pregnancy

Spironolactone-HCTZ is generally not recommended during pregnancy. Consultation with a healthcare provider is necessary to discuss the potential risks and benefits.

Use of spironolactone-HCTZ while breastfeeding

Spironolactone-HCTZ may pass into breast milk and may have adverse effects on the nursing infant. It is generally not recommended while breastfeeding. Consultation with a healthcare provider is necessary to discuss alternative treatment options.

Possible side effects of spironolactone-HCTZ

Common side effects of spironolactone-HCTZ may include dizziness, lightheadedness, drowsiness, headache, stomach upset, increased urination, and changes in potassium levels. Serious side effects are rare but can include allergic reactions, electrolyte imbalances, muscle weakness, and kidney problems. Get medical help right away if you have any serious side effects such as an allergic reaction. Symptoms include hives, trouble breathing, shortness of breath, chest pain, swelling of the face, tongue or throat, skin rash, and severe skin reactions. Promptly report any adverse effects to a healthcare professional for medical advice.

Interactions with other drugs

Spironolactone-HCTZ may interact with certain medications, including eplerenone, angiotensin-converting enzyme (ACE) inhibitors such as lisinopril, angiotensin II antagonists (angiotensin receptor blockers) such as valsartan, nonsteroidal anti-inflammatory medications (NSAIDS) such as ibuprofen and naproxen, digoxin, diuretics (water pills) including potassium-sparing diuretics such as amiloride or triamterene, lithium, potassium supplements, and trimethoprim. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medication, salt substitutes, supplements, and vitamins you are taking to avoid potential adverse effects and drug interactions.

Similar drugs to spironolactone-HCTZ

Other combination medications used to treat high blood pressure and fluid retention include Lisinopril-HCTZ, Amlodipine-Benazepril, and Losartan-HCTZ.


  • FDA Prescribing Information for Spironolactone-HCTZ
  • MHRA product information for Spironolactone-HCTZ
  • NHS UK
  • Drugs.com
  • WebMD

About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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