Used for Hypertension

Are you tired of high medication costs? Our service offers unbeatable savings on your spironolactone prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by various FDA-approved generic manufacturers.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

spironolactone cost saving options available to you

  • Qualified

    Rx Advantage Card

    NowPatient's Rx Advantage card is a simple & convenient way to save money on your spironolactone

    You can save up to 90%

  • Unavailable

    Canadian Prescription Savings

    Manufactured by
    Powered by
    Buy your spironolactone without insurance from Canada at discounts of up to 90% using NowPatient's Canadian Prescription savings program.
  • Unavailable

    Drug Coupons

    Obtain your spironolactone for as little as $0 per fill. Suitable for insured individuals only.
  • Unavailable

    Patient Assistance Programs

    Obtain your spironolactone at no cost. Suitable for insured, underinsured and uninsured individuals

How it works

How to Lower Your Drug Costs

  • swoosh
    View programs

    View the savings programs that are available

  • swoosh
    Select program

    Pick the program that is suitable for you

  • swoosh

    If required, complete the online qualification check

  • swoosh
    Start Saving

    Enroll & Start Saving



Why Choose Our Service?

  • black dot icon

    Comprehensive Coverage

    Our service covers a wide range of medications, ensuring you can find savings on almost any prescription.

  • emoji icon

    Easy to Use

    Our website is user-friendly, allowing you to quickly find and apply discounts.

  • check icon

    Trusted by Many

    Thousands of users trust us to help them save on their medication costs every day.


Start Saving Today!

Lower the cost of your spironolactone prescription

Join the many satisfied customers who have already benefited from our prescription discount service.

Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

spironolactone Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is spironolactone available in?

What dosages is spironolactone available in?

spironolactone is available as a 25 mg, 50 mg, and 100 mg tablet.

What is spironolactone used for?

What is spironolactone used for?

spironolactone is a potassium-sparing diuretic (water pill) used to treat hypertension, primary aldosteronism (a hormone imbalance), or swelling due to liver damage (cirrhosis), nephrotic syndrome (a rare kidney condition), or congestive heart failure.

How does spironolactone work?

How does spironolactone work?

spironolactone is a potassium-sparing diuretic (water pill) that works in your kidneys you urinate more without lowering the amount of potassium. This helps lower the amount of fluid in your blood vessels and other areas of your body.

How do I take spironolactone?

How do I take spironolactone?

spironolactone can be taken as a single dose once a day or split into smaller doses and be taken twice a day.

Is it safe for me to take spironolactone?

Is it safe for me to take spironolactone?

spironolactone is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. ALDACTAZIDE is contraindicated in patients with hyperkalemia, Addison’s disease, or in those taking eplerenone.

spironolactone Common Side Effects

spironolactone Common Side Effects

Common side effects of spironolactone include:

  • Dizziness
  • Headache
  • Sleepiness
  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach cramps
  • Enlargement of male breasts
  • Breast pain
  • Lower sex drive
  • Sexual dysfunction
  • Irregular or lack of menstrual periods
  • Leg cramps
  • Higher potassium levels
  • Lower sodium levels
spironolactone Serious Side Effects

spironolactone Serious Side Effects

Serious side effects are rare with spironolactone. Contact your healthcare provider immediately if you experience any of the following.

  • High potassium levels: muscle weakness, numbness, a tingling sensation, racing heart, trouble catching your breath, chest pain, nausea, vomiting
  • Abnormal electrolyte levels: muscles cramps, fainting, irregular heartbeats, seizures
  • Kidney failure: not urinating as much as usual, muscle cramps, nausea, vomiting, tiredness, swelling
  • Serious skin reactions: sore throat, fever, tiredness, trouble swallowing, stinging sensation in the eyes, body aches, rash, itchiness, peeling or blistering of the skin
Effects of other drugs, drug classes and over-the-counter products on spironolactone

Effects of other drugs, drug classes and over-the-counter products on spironolactone

ACE inhibitors, Angiotensin II receptor antagonists, aldosterone blockers, potassium supplements, heparin, low molecular weight heparin, and other drugs known to cause hyperkalemia. Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. Nonsteroidal anti-inflammatory drugs (NSAIDs): In some patients, the administration of an NSAID can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing, and thiazide diuretics. Combination of NSAIDs, e.g., indomethacin, with potassium-sparing diuretics has been associated with severe hyperkalemia. Lithium: Lithium generally should not be given with diuretics. Diuretics: May reduce the renal clearance of lithium and add a high risk of lithium toxicity. Cholestyramine: Hyperkalemic metabolic acidosis has been reported with concomitant use.

Who makes spironolactone?

Who makes spironolactone?

Various FDA-approved generic manufacturers

Is spironolactone safe in pregnancy?

Is spironolactone safe in pregnancy?

It is not known if spironolactone will harm your unborn baby. If you become pregnant while receiving spironolactone, talk to your healthcare provider.


What to do if you missed your spironolactone dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
dollar sign

Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

FAQ logo

Things to know

Now Patient Data Security

Data Security

Our Commitment to You.

Find out moreNow Patient Data SecurityNow Patient Data Security

What is NowPatient

Online Pharmacy & Telehealth

NowPatient is an online pharmacy & telehealth service that is available in the US and UK. Our service is FREE and packed with useful features that can help you save money on the cost of your medications, access virtual treatments, and provide tools that can help improve your overall health.  Get started today and benefit from medication reminders, private treatment plans, NHS online pharmacy, GP appointment booking, Rx savings card, Drug Coupons, US drug savings programs, health conditions information, Drug Information, genetic testing, home test kits, BMI Risks, Type 2 Diabetes Riskspollen meter, air quality monitor, and lots more!

A laptop screen displays a dashboard with various health metrics and notifications. Widgets include drug coupons, home health testing, genetic risk, diabetes risk, BMI, pollen meter, and air quality.


To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.

Download our app today

A collage showing a map with pharmacies, a questionnaire, medication details, and a person video chatting on a screen.

Can I trust NowPatient

Meet our medical team

We are a passionate group of clinicians and medical writers covering a broad range of specialities with experience operating in health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do. You can read more about our medical team by visiting the medical team page or learn more about how we curate content by visiting our editorial process

Your Questions Answered

For your peace of mind, we can answer your questions quickly

We have a comprehensive list of FAQ’s on each feature page. Alternatively, for broader questions around our service just click the button below.
Find your answers