PANZYGA
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Manufactured by Pfizer
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PANZYGA Uses, Side Effects, Interactions, Warnings & Dosing
What is PANZYGA?
PANZYGA is the brand name for immune globulin and is available as an IV infusion.
What dosages is PANZYGA available in?
PANZYGA is available as a solution containing 10% IgG (100 mg/mL) for an IV infusion.
What is PANZYGA used for?
PANZYGA is an Immune globulin and is used for the following:
Conditions where your immune system is missing or not working as it should:
- Trouble fighting infections (primary humoral immunodeficiency or PI)
- Low platelets (chronic (long-term) immune thrombocytopenia or ITP)
- Nerve damage (chronic inflammatory demyelinating polyneuropathy or CIDP)
How does PANZYGA work?
PANZYGA is a replacement for immunoglobulin G (IgG). IgG is an antibody that your immune system makes to help protect against organisms like viruses, bacteria, and fungi. Certain medical conditions can cause your immune system to be too active or too inactive. The exact way PANZYGA works to treat these medical conditions isn’t fully known. It’s thought to boost your immune system to help prevent infections. It also might help prevent an overly active immune system from attacking parts of your own body by mistake.
How do I take PANZYGA?
Your dose of PANZYGA depends on things like your body weight, lab results, and what you’re using Panzyga for. In general:
Trouble fighting infections (PI)
- Adults and children age 2 years and older: The typical dose is 300 mg/kg to 600 mg/kg infused into the veins (IV) once every 3 to 4 weeks
Low platelets (ITP)
- Adults: The typical dose is 1 gram/kg infused IV once daily for 2 days.
Nerve damage (CIDP)
- Adults: Typically, you’ll start with a loading dose of 1 gram/kg infused IV once daily for 2 days. Then, you’ll continue with a maintenance dose of 1 gram/kg to 2 gram/kg split into 2 doses (1 dose given daily for 2 days in a row), once every 3 weeks.
Is it safe for me to take PANZYGA?
PANZYGA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- History of anaphylactic or severe systemic reactions to human immune globulin
- IgA-deficient patients with antibodies against IgA and a history of hypersensitivity
PANZYGA Common Side Effects
Common side effects of PANZYGA:
- Stomach pain
- Sinus infection/inflammation
- Extreme tiredness
- Bronchitis
- Headache
- Fever
- Nausea
- Vomiting
- Dizziness
- Weakness, pale-colored skin, or other symptoms of low red blood cell count
PANZYGA Serious Side Effects
Serious side effects are rare with PANZYGA. Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: difficulty breathing, hives, itching, fast heartbeat, tightness in the throat, nausea, stomach pain, dizziness, lightheadedness, swelling in the face or tongue
- Swelling in the brain: severe headache, neck stiffness, sensitivity to light, painful eye movements
- Lung problems: severe breathing problems, chest pain or tightness
- Dangerously high blood pressure: severe headache, dizziness, blurry vision, shortness of breath, lightheadedness
- Kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
- Blood clots: lungs (cough, difficulty breathing, chest pain); legs (redness, pain, tenderness, swelling of the skin); heart attack (chest pain, pain in the arms or shoulders, pain in the neck or jaw); stroke (difficulty speaking, numbness on one side of the body, confusion)
- Breakdown of red blood cells: tiredness, dizziness, weakness, yellowing of the skin or eyes, dark-colored urine
Effects of other drugs, drug classes and over-the-counter products on PANZYGA
The following medications may interact with PANZYGA:
- The passive transfer of antibodies may confound the results of serological testing
- The passive transfer of antibodies may interfere with the immune response to live viral vaccines, such as measles, mumps, and rubella
Who makes PANZYGA?
Pfizer
Is PANZYGA safe in pregnancy?
It is not known if PANZYGA harms your unborn baby. NYVEPRIA should be given to a pregnant woman only if clearly needed. Talk to your doctor about stopping PANZYGA if you are pregnant or planning to become pregnant.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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