Omeprazole sodium

Omeprazole sodium Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Omeprazole-Sodium Bicarbonate
    Generic for Zegerid
    30 capsules $20.1 USD
    Save $2052.90
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Do you need a prescription for omeprazole sodium?

Yes, omeprazole sodium is only available with a valid physician Rx.

How much is omeprazole sodium without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase omeprazole sodium, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for omeprazole sodium in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a omeprazole sodium savings card?

Yes. Save up to 90% on your omeprazole sodium with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a omeprazole sodium coupon provider in the US?

No. Now Patient does not provide omeprazole sodium coupons or FREE omeprazole sodium samples.

Do you accept commercial, Medicare or Medicaid coverage for omeprazole sodium in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much omeprazole sodium?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using omeprazole sodium. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much omeprazole sodium. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic omeprazole sodium?

Generic omeprazole sodium refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of omeprazole sodium

Omeprazole sodium is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various gastrointestinal conditions, including gastroesophageal reflux disease (GERD) and stomach ulcers.

Active ingredient of omeprazole sodium

The active ingredient of omeprazole sodium is omeprazole.

US brand name of omeprazole sodium and manufacturer

Omeprazole sodium is available in the US under various brand names, including Prilosec and Zegerid. It is manufactured by various pharmaceutical companies.

UK brand name of omeprazole sodium and manufacturer

In the UK, omeprazole sodium is available under various brand names, including Losec. The manufacturer may vary depending on the brand name.

Prescription requirement for omeprazole sodium

A prescription (Rx) is required for omeprazole sodium in both the US and the UK.

Availability of omeprazole sodium in the UK with NHS prescription

Omeprazole sodium is available in the UK with an NHS prescription.

Conditions treated by omeprazole sodium

Omeprazole sodium is a combination of omeprazole and sodium bicarbonate. It is used for the treatment of various gastrointestinal and esophagus conditions, including heartburn (gastroesophageal reflux disease/GERD), stomach ulcers, duodenal ulcers, and Zollinger-Ellison syndrome. It is also prescribed in combination with antibiotics for the eradication of Helicobacter pylori, a bacteria associated with stomach ulcers.

How does omeprazole sodium work?

Omeprazole sodium belongs to a class of medications called proton pump inhibitors (PPIs). It works by reducing the production of acid in the stomach. By inhibiting the activity of the proton pump, omeprazole sodium helps reduce the acidity in the stomach, providing relief from acid-related symptoms and promoting the healing of stomach ulcers. Sodium bicarbonate, is an antacid that neutralizes excess gastric acid in the stomach.

Dosage forms of omeprazole sodium available

Omeprazole sodium is available in various formulations, such as oral capsules and oral powder for suspension.

Dosage of omeprazole sodium

The dosage of omeprazole sodium may vary depending on the specific gastrointestinal condition being treated, the patient’s age, and other individual factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider.

Directions for omeprazole sodium use

Omeprazole sodium should be taken exactly as directed by the healthcare provider. The medication is usually taken once daily, preferably in the morning on an empty stomach before breakfast. It should be swallowed whole with water and should not be crushed or chewed.

Warnings and precautions for omeprazole sodium

  • Omeprazole sodium should be used with caution in individuals with certain medical conditions, such as liver disease. Dose adjustments may be necessary
  • Long-term use of omeprazole may be associated with certain risks, such as an increased risk of fractures, vitamin B12 deficiency, and certain gastrointestinal infections. Regular monitoring and appropriate supplementation may be necessary
  • It may interact with certain medications, including clopidogrel and certain antifungal drugs. Inform the healthcare provider about all medications being taken
  • Tell your healthcare provider if you are of Asian descent and have ever had low blood levels of magnesium, calcium, or potassium, hypoparathyroidism, osteoporosis, systemic lupus erythematosus, or liver disease

Use of omeprazole sodium during pregnancy

The use of omeprazole sodium during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of omeprazole sodium while breastfeeding

Omeprazole sodium is excreted in breast milk but is generally considered safe to use while breastfeeding. It is recommended to consult a healthcare provider before using omeprazole sodium while breastfeeding.

Possible side effects of omeprazole sodium

Common side effects of omeprazole sodium may include headache, lightheadedness, diarrhea, stomach pain, and nausea. Serious side effects such as allergic reactions are rare. Get medical help immediately if you have symptoms such as a rash, swelling of the face, tongue, or throat, chest pain, or trouble breathing.

Interactions with other drugs

Omeprazole may interact with certain medications, including warfarin, atazanavir, cilostazol, citalopram, clopidogrel, diazepam, digoxin, erlotinib, itraconazole, ketoconazole, methotrexate, nelfinavir, phenytoin, rifampin, St John’s wort, rilpivirine or tacrolimus.

It is important to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter (OTC) drugs, dietary supplements, multivitamins, and herbal products, to avoid any adverse effects and potential drug interactions.

Similar drugs to omeprazole sodium

Other proton pump inhibitors used for the treatment of gastrointestinal conditions include esomeprazole, lansoprazole, and pantoprazole.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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