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Minocycline HCI Extended Release is available as a 45 mg, 55 mg, 65 mg, 80 mg, 90 mg, 105 mg, 115 mg, and 135 mg extended-release oral tablet.

Minocycline HCI Extended Release is a tetracycline antibiotic and is used for the following:

• Moderate-to-severe acne
• Respiratory tract infections, including in the nose, throat, and lungs
• Sexually transmitted infections (STIs) like chlamydia, gonorrhea, chancroid, and syphilis
• Skin infections
• Urinary tract infections (UTIs)
• Rickettsial infections (usually from ticks, fleas, or mites), such as Rocky Mountain spotted fever and typhus fever
• Other infections such as anthrax, plague, cholera, and more. Minocycline can be used to treat many other less common infections not listed here.

Minocycline HCI Extended Release is a tetracycline antibiotic. It prevents bacteria from making certain proteins, which stops them from multiplying and spreading in your body. For acne, minocycline lowers the amount of the P. acnes bacteria that live naturally on your skin. This can help lessen inflammation and acne.

Minocycline HCI Extended Release is dosed as follows:

• Adults: Your dose will depend on the reason why you’re taking minocycline. For most infections, the typical dose is 200 mg by mouth for one time, then 100 mg by mouth every 12 hours. Another dosing option is 100 mg or 200 mg by mouth for one time, then 50 mg by mouth 4 times a day
• Children over 8 years old: Your child’s provider will calculate their dose based on their body weight. The typical dose is 4 mg/kg of weight (up to 200 mg per dose) by mouth for one time, then 2 mg/kg of weight(up to 100 mg per dose) by mouth every 12 hours
• Extended-release tablets (Minocycline HCI Extended Release, Minolira) or capsules (Ximino) for acne only (ages 12 years and older): Your dose will be based on your body weight. The typical dose is 1 mg/kg of weight by mouth once daily for 12 weeks
• Minocycline is also available as an intravenous (IV) injection that’s given by a healthcare provider

Minocycline HCI Extended Release is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. This drug is contraindicated in persons who have shown hypersensitivity to
any of the tetracyclines.

Common side effects of Minocycline HCI Extended Release:

• Headache
• Feeling tired
• Dizziness
• Itching

Serious side effects are rare with Minocycline HCI Extended Release. Contact your healthcare provider immediately if you experience any of the following.

• Severe allergic reaction: trouble breathing; hives; swelling of the face, lips, tongue, or throat
• Severe skin reactions: rash, blisters, red skin
• Severe diarrhea
• High pressure in the brain: headache, dizziness, blurred vision, swelling inside eye, vision changes, double vision, vision loss

The following medications may interact with Minocycline HCI Extended Release:

• Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage
• The concurrent use of tetracycline and methoxyflurane has been reported to result in fatal renal toxicity
• To avoid contraceptive failure, female patients are advised to use a second form of contraceptive during treatment with minocycline

Various FDA-approved generic manufacturers

Minocycline HCI Extended Release may harm your unborn baby. Taking Minocycline HCI Extended Release while you are pregnant may cause serious side effects on the growth of bone and teeth of your baby. Talk to your doctor before taking Minocycline HCI Extended Release if you plan to become pregnant, or if you are already taking Minocycline HCI Extended Release and plan to become pregnant. Stop taking Minocycline HCI Extended Release and call your doctor right away if you become pregnant while taking Minocycline HCI Extended Release.

• Solodyn