MercaptopurinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Mercaptopurine
    Generic for Purinethol
    30 tablets $15.6 USD
    Save $120.00
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Do you need a prescription for mercaptopurine?

Yes, mercaptopurine is only available with a valid physician Rx.

How much is mercaptopurine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase mercaptopurine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for mercaptopurine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a mercaptopurine savings card?

Yes. Save up to 90% on your mercaptopurine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a mercaptopurine coupon provider in the US?

No. Now Patient does not provide mercaptopurine coupons or FREE mercaptopurine samples.

Do you accept commercial, Medicare or Medicaid coverage for mercaptopurine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much mercaptopurine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using mercaptopurine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much mercaptopurine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of mercaptopurine and manufacturer

Mercaptopurine is FDA approved and available in the US under the brand names Purixan and Purinethol. It is manufactured by Teva Pharmaceuticals.

UK brand name of mercaptopurine and manufacturer

Mercaptopurine is available in the UK under the brand name Purinethol. It is also manufactured by Teva Pharmaceuticals.

Is mercaptopurine available in the UK on the NHS?

Yes, mercaptopurine is available on the NHS in the UK.

Prescription requirement for mercaptopurine

Mercaptopurine is a prescription medication and requires a prescription from a healthcare provider.

Active ingredient of mercaptopurine and mechanism of action

Mercaptopurine contains the active ingredient mercaptopurine. It belongs to a class of medications known as antimetabolites. It works by interfering with the growth and replication of cancer cells.

Uses of mercaptopurine

Mercaptopurine is a purine antagonist, primarily used for the treatment of certain types of cancer, including acute lymphocytic leukemia (ALL; also called acute lymphoblastic leukemia) and acute myeloid leukemia (AML). It is also used off-label for other conditions, such as inflammatory bowel disease.

Forms of mercaptopurine

Mercaptopurine is available in the form of oral tablets. The specific strength and formulation will depend on the individual patient’s needs and the prescribing healthcare provider’s instructions. Store mercaptopurine at room temperature, away from moisture, heat, and direct light.

Dosage of mercaptopurine

The dosage of mercaptopurine tablets will vary depending on the specific indication, the individual patient’s body weight, and other factors. It is important to follow the dosage instructions provided by your healthcare provider.

If you forget to take your medication, take the missed dose as soon as you can. If it is almost time for your next dose, skip the missed dose and take your next dose at the usual time..

Precautions and warnings for mercaptopurine

  • Mercaptopurine should only be used under the supervision of a healthcare provider experienced in the use of chemotherapy medications. Patients taking mercaptopurine for the treatment of Crohn’s disease or ulcerative colitis have developed hepatosplenic T cell lymphoma, a very serious type of cancer
  • It can have serious side effects, including bone marrow suppression, a reduction in the number of white blood cells and platelets in your blood and an increased risk of infections. Regular monitoring of blood counts is necessary during treatment
  • Tell your doctor if you have ever had liver disease, kidney disease, a condition where your body cannot produce enough of the enzyme thiopurine methyltransferase (TPMT), or any type of infection
  • It is essential to discuss the potential risks and benefits of mercaptopurine with your healthcare provider, especially if you have a history of certain medical conditions or if you are pregnant or planning to become pregnant
  • Speak to your doctor if you have had an allergic reaction to mercaptopurine or azathioprine in the past
  • You are advised not to breast-feed while taking mercaptopurine or for 1 week after stopping it

Side effects of mercaptopurine

Common side effects of mercaptopurine may include nausea, vomiting, diarrhea, mouth sores, sore throat, loss of appetite, tiredness, and hair loss. It can also cause more serious side effects, such as bone marrow suppression, liver toxicity, and increased risk of infections. It is important to report any persistent or concerning adverse effects to your healthcare provider.

Interactions with other drugs

Mercaptopurine may have drug interactions with other medications, including certain immunosuppressants, aminosalicylates such as olsalazine and sulfasalazine, anticoagulants such as warfarin, allopurinol and medications that affect liver enzymes. It is important to inform your healthcare provider about all the medications you are taking including vitamis and supplements to ensure there are no potential interactions.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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