Lactulose Generic

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Lactulose
    Generic for Cephulac
    473mL solutions $14.5 USD
    Save $16.01
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Do you need a prescription for lactulose?

Yes, lactulose is only available with a valid physician Rx.

How much is lactulose without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase lactulose, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for lactulose in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a lactulose savings card?

Yes. Save up to 90% on your lactulose with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a lactulose coupon provider in the US?

No. Now Patient does not provide lactulose coupons or FREE lactulose samples.

Do you accept commercial, Medicare or Medicaid coverage for lactulose in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much lactulose?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using lactulose. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much lactulose. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic lactulose?

Generic lactulose refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of lactulose

Lactulose is approved by the U.S. Food and Drug Administration (FDA) for the treatment of constipation and hepatic encephalopathy.

Active ingredient of lactulose

The active ingredient of lactulose is lactulose.

US brand name of lactulose and manufacturer

Lactulose is available in the US under various brand names, including Cephulac, Cholac, Chronulac, Constulose, Generlac, Kristalose and Enulose. The manufacturers may vary depending on the brand names.

UK brand name of lactulose and manufacturer

In the UK, lactulose is available under various brand names, including Duphalac and Lactugal. The manufacturers may vary depending on the brand names.

Prescription requirement for lactulose

A prescription (Rx) is required for lactulose in both the US and the UK.

Availability of lactulose in the UK with NHS prescription

Lactulose is available in the UK with an NHS prescription.

Conditions treated by lactulose

Lactulose is used for the treatment of constipation, chronic constipation and hepatic encephalopathy, a condition that affects the brain function in people with liver disease.

How does lactulose work?

Lactulose is a disaccharide, absorbed poorly from the gastrointestinal tract. Enzymes able to break down lactulose are not present in the human gastrointestinal tissue. Lactulose works by drawing water into the intestine, softening the stool and increasing bowel movements. In the case of hepatic encephalopathy, lactulose reduces the production and absorption of ammonia in the intestine, helping to reduce its concentration in the blood, which can alleviate symptoms associated with liver disease.

Forms of lactulose available

Lactulose is available in liquid form for oral administration.

Dosage of lactulose

Your dose of lactulose may vary depending on your specific condition and response to the medication. It is important to follow the recommended dosage instructions and medical advice provided by a healthcare professional.

Directions for lactulose use

Lactulose should be stored at room temperature and taken exactly as directed by the healthcare provider. It is usually taken orally, with or without food. It may take a few days for the full effect of Lactulose to be noticed.

Warnings and precautions for lactulose

  • Lactulose may have certain risks and potential side effects. It is important to discuss these with a healthcare provider before starting the medication
  • Should not be used in those who follow a low lactose or galactose diet
  • Lactulose should be used with caution in individuals with diabetes, as it contains sugar and may affect blood glucose levels

Use of lactulose if pregnant or planning pregnancy

The use of lactulose during pregnancy should be discussed with a healthcare provider. It is generally considered safe for use during pregnancy. It is not known if lactulose passes into breast milk. Speak to your doctor before breast-feeding.

Possible side effects of lactulose

Common side effects of lactulose may include diarrhea (which may cause electrolyte problems), abdominal discomfort, bloating and flatulence. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider. Serious allergic reactions to lactulose are rare. Get medical help immediately however, if you notice symptoms such as a rash, swelling, or itching (especially of the face, tongue or throat), have difficulty breathing, or severe dizziness.

Similar drugs to lactulose

Other laxatives, such as polyethylene glycol (PEG) may be used as alternatives for the treatment of constipation. Some antacids containing magnesium and/or aluminium may interact with lactulose, however no other drug interactions are associated with mixing lactulose with other prescription drugs, over-the-counter medicines, supplements or herbal remedies.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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