ISTODAX®

Coupons, Savings & Patient Assistance

Learn more about ISTODAX® and see what savings options may be available to you that can help bring down the cost of your medication.

Options may include Rx Advantage Card, Copay assistance & Coupons, or Patient Assistance Programs. Suitable for insured, underinsured or uninsured individuals. Pay as little as $0 per fill.

Manufactured by Bristol-Myers Squibb.

This content is intended for US audiences only

Drug savings options

Qualified

Rx Advantage Card for ISTODAX®

Good News! You can save up to 90% savings on the cost of your ISTODAX® when using the FREE NowPatient’s Rx Advantage Card at your local pharmacy.

Coming Soon

Canada Pharmacy for ISTODAX®

Use our trusted Canada Pharmacy partner, Prescription Help, for your ISTODAX®. It’s suitable if you are cash paying, uninsured or insured and cannot afford your copays.

Options
Coming Soon
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Coming Soon
Unavailable

Copay Assistance for ISTODAX®

Unfortunately, Bristol-Myers Squibb who manufactures ISTODAX®, does not offer a co-pay assistance program at this time. Please check back regularly as this situation may change.

Available

Patient Assistance Programs for ISTODAX®

Bristol-Myers Squibb who manufactures ISTODAX®, offers a patient assistance program for those who are unable to afford their medication or do not have adequate coverage.

If you qualify, we can supply you with all the details to help you get started with your enrollment.

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Written by Rajive Patel, BPharm
Updated on 4 Apr 2024
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Learn more about ISTODAX

What is ISTODAX?

What is ISTODAX?

ISTODAX is the brand name for romidepsin and is available as an injection for IV use.

What dosages is ISTODAX available in?

What dosages is ISTODAX available in?

ISTODAX is available as a single-dose vial that contains 10 mg of romidepsin.

What is ISTODAX used for?

What is ISTODAX used for?

ISTODAX is a histone deacetylase (HDAC) inhibitor indicated for the treatment of
cutaneous T-cell lymphoma (CTCL) in adult patients who have received at least one prior
systemic therapy

How does ISTODAX work?

How does ISTODAX work?

ISTODAX works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

How do I take ISTODAX?

How do I take ISTODAX?

ISTODAX is dosed as follows:
14 mg/m2 administered intravenously over a 4-hour period on days 1, 8, and 15 of
a 28-day cycle. Repeat cycles every 28 days provided that the patient continues to
benefit from and tolerates the drug.
Discontinue or interrupt treatment (with or without dose reduction to 10 mg/m2) to
manage drug toxicity.
Reduce starting dose in patients with moderate and severe hepatic impairment.

Is it safe for me to take ISTODAX?

Is it safe for me to take ISTODAX?

ISTODAX is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

ISTODAX Common Side Effects

ISTODAX Common Side Effects

Common side effects of ISTODAX:

  • Nausea
  • Fatigue
  • Infections
  • Vomiting
  • Weight loss
  • Heart rhythm changes
  • Altered taste
  • Constipation
ISTODAX Serious Side Effects

ISTODAX Serious Side Effects

Serious side effects are rare with ISTODAX. Contact your doctor or seek medical help if you experience any of the following.
Low blood cell counts
Serious infections
Changes in your heartbeat
Tumor lysis syndrome

Effects of other drugs, drug classes and over-the-counter products on ISTODAX

Effects of other drugs, drug classes and over-the-counter products on ISTODAX

The following medications may interact with ISTODAX:

  • Carefully monitor prothrombin time (PT) and International Normalized Ratio (INR) in
  • patients concurrently administered ISTODAX and warfarin or coumarin derivatives.
  • Monitor for toxicities related to increased romidepsin exposure when co-administering
  • romidepsin with strong CYP3A4 inhibitors.
  • Avoid use with rifampin and strong CYP3A4 inducers.
Who makes ISTODAX?

Who makes ISTODAX?

Bristol-Myers Squibb

Is ISTODAX safe in pregnancy?

Is ISTODAX safe in pregnancy?

ISTODAX may harm your unborn baby.
Females who are able to become pregnant:
Your healthcare provider will perform a pregnancy test within 7 days before you start treatment with ISTODAX.
You should avoid becoming pregnant during treatment with ISTODAX and for 1 month after the last dose.
You should use effective birth control (contraception) during treatment with ISTODAX and for 1 month after your last dose.
ISTODAX may affect the way estrogen-containing birth control works. Talk to your healthcare provider for more information about other types of birth control to use during treatment with ISTODAX.
Tell your healthcare provider right away if you become pregnant or think you may be pregnant during
treatment with ISTODAX.

Males with a female sexual partner who can become pregnant:
ISTODAX can harm the unborn baby of your partner.
You should use a condom and avoid fathering a child during treatment with ISTODAX and for 1 month after treatment with ISTODAX. Talk to your healthcare provider if this is a concern for you.

pill

What to do if you missed your ISTODAX ® dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects

What can I do if I am commercially insured but cannot afford my ISTODAX ®?

If you are commercially insured and you cannot afford your ISTODAX® copay or co-insurance you have four options:

Option

Savings Information

Copay Assistance Program

Check at the top of the page to see if there is a ISTODAX® Copay Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your ISTODAX® for as little as $0 per fill.

Patient Assistance Program

Check at the top of the page to see if there is a ISTODAX® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your ISTODAX® for no cost.

Rx Advantage Card

You can use the NowPatient Rx Advantage Card which removes the constraints of insurance and the cost can be typically lower than your plan copay or co-insurance. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

Medicaid

If the above options are not feasible then you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

What can I do if I am uninsured and cannot afford my ISTODAX ®?

If you are uninsured and you cannot afford your ISTODAX®, then you have three options:

Option

Savings Information

Patient Assistance Program

Check at the top of the page to see if there is a ISTODAX® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your ISTODAX® for no cost.

Rx Advantage Card

You can use the NowPatient Rx Advantage Card at a local pharmacy and obtain prices that are typically 80% of standard retail prices.

Medicaid

If the above options are not feasible then you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

What can I do if I am insured with Medicare and cannot afford my ISTODAX ®?

If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have four options:

Option

Savings Information

Patient Assistance Program

Check at the top of the page to see if there is a ISTODAX® Patient Assistance Program sponsored by the manufacturer. You can check your eligibility to see if you qualify. If you qualify you could obtain your ISTODAX® for no cost.

Rx Advantage Card

You can use the NowPatient Rx Advantage Card which removes the constraints of insurance and the cost can be typically lower than your plan copay or co-insurance. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

Low Income Subsidy

If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

Medicaid

The final option is to check ‘dual eligibility’ to Medicaid in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

Am I eligible for the Rx Advantage Card and how much does ISTODAX ® cost without insurance?

Our website gives savings options to customers who wish to purchase ISTODAX®, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.

What will my out-of-pocket cost be for ISTODAX ® when using the Rx Advantage Card?

Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for ISTODAX® using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.

Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.

Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?

No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket ISTODAX® cash price you pay can be typically cheaper than your plan copay.

Does the Rx Advantage Card work with Commercial Insurance?

We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket ISTODAX® cash price you pay can be typically cheaper than your plan copay.

How do I check prices for ISTODAX ® and how do I use the Rx Advantage Card?

You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your ISTODAX® Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.

Do I need to pay for the Rx Advantage Card?

No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.

Is there a ISTODAX ® co-pay program?

You can check the top of the page to see if there is an option for a ISTODAX® co-pay card. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.

What are the eligibility requirements for a ISTODAX ® co-pay card and how much do I have to pay?

Eligibility requirements vary between pharmaceutical companies. However, they almost all require you to be commercially insured. If you qualify there is no cost to you. It is a FREE program.

Can I enroll in the ISTODAX ® co-pay program if I have state, federal, or other government insurance?

Most likely, no. The copay card program is primarily designed for commercially or privately insured individuals. However, if you are finding it difficult to afford your medication, then there are other forms of assistance. For example, you can apply for LIS (Low Income Subsidy) or extra help is available online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778). As well, you can look at state assistance programs like Medicaid.

Can I enroll in the ISTODAX ® co-pay program if I have no insurance?

Most likely No. However, many pharmaceutical companies offer fully funded free programs for uninsured persons. These programs are called Patient Assistance Programs (PAP) and NowPatient provides a useful resource to check program availability and eligibility.

How can I check if I am eligible for the ISTODAX ® co-pay program?

If a ISTODAX® co-pay card exists, you will see it as a savings option at the top of the page. You can select the option and it will direct you to an eligibility checker. If you qualify you will be prompted to create an account with NowPatient, from where you will be able to access the instructions on how to enroll.

How do I use the ISTODAX ® co-pay card?

Once you are enrolled into the program you will be able to download the card. When you next fill your Rx, simply present the co-pay card to the pharmacist. The Pharmacist will use the card to process and submit your claim. You will then be provided with your discount. The program cost is covered by the pharmaceutical company.

Is there a ISTODAX ® Patient Assistance Program (PAP)?

You can check the top of the page to see if there is an option for a ISTODAX patient assistance program. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.

What are the eligibility requirements for a ISTODAX ® PAP and how much do I have to pay?

Eligibility requirements vary between pharmaceutical companies. However, they almost all require you to be uninsured, underinsured with no drug coverage, or insured but unable to afford your co-pay or co-insurance contribution. If you qualify there is no cost to you. It is a FREE program funded by the pharmaceutical company.

Can I enroll in a ISTODAX ® PAP if I have state, federal, or other government insurance?

It is possible. Some programs do not allow any insured individuals to apply, however, some programs do have exceptions. If you find that you do not qualify and are finding it difficult to afford your medication, then there are other forms of assistance. For example, you can apply for LIS (Low Income Subsidy) or extra help is available online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778). As well, you can look at state assistance programs like Medicaid.

Can I enroll in a ISTODAX ® PAP if I have no insurance?

Yes. Most programs are open to individuals who are uninsured and meet income eligibility criteria.

How can I check if I am eligible for the ISTODAX ® PAP?

If a ISTODAX® patient assistance program exists, you will see it as a savings option at the top of the page. You can select the option and it will direct you to an eligibility checker. If you qualify you will be prompted to create an account with NowPatient, from where you will be able to access the instructions on how to enroll.

How do I use the ISTODAX ® PAP to obtain my medication?

Once you are enrolled in the program you will be advised by the pharmaceutical company how they will make supplies to you. In most cases, they will ship the medication through their nominated mail-order pharmacy, directly to you. However, depending on the nature of the medication, the pharmaceutical company may opt to provide you with a pharmacy card (which you can redeem against your medication for FREE at your nearby pharmacy) or ship the medication directly to your healthcare provider (HCP).

Refills are usually handled by the pharmaceutical company.

I am insured but I do not qualify for patient assistance or copay assistance for ISTODAX ®. Is there any other form of assistance that can help with the costs of my existing copays or co-insurance?

There are a number of resources available such as charitable foundations that may be able to provide assistance for your ISTODAX®:

Patient Access Network Foundation (PAN) assistance for ISTODAX®

If you are having trouble paying for your ISTODAX® medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for ISTODAX® you will need to meet one or all of the following criteria:

  • Your income is below 400% of the federal poverty level
  • ISTODAX® is prescribed for an approved FDA indication
  • You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
  • You have Medicare insurance coverage that covers ISTODAX®
  • If ISTODAX® is listed on PAN's list of covered medications

You can check the Patient Access Network Foundation Website for more information.

HealthWell Foundation Copay Program for ISTODAX®

If you are having trouble paying for your ISTODAX® medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for ISTODAX® you will need to meet the following criteria:

  • You live in and are being treated in the United States
  • You are insured and your plan covers ISTODAX®
  • If ISTODAX® is listed on the HealthWell Foundation's list of covered medications

You can check the HealthWell Foundation Website for more information.

Patient Advocate Foundation Co-Pay Relief Program for ISTODAX®

Patient Advocate Foundation's Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your ISTODAX® treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for ISTODAX® you will need to meet the following criteria:

  • You must be currently insured and have coverage for ISTODAX®
  • You must have a confirmed diagnosis and treatment plan
  • You must reside and receive treatment in the United States
  • Your Income must fall at or below 3000r 4000f the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
  • Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.

You can check the Patient Advocate Foundation Website for more information.

What should I do if I take too much ISTODAX ®?

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using ISTODAX®. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much ISTODAX®. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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