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Updated on 26 Apr 2024

GENOTROPIN Uses, Side Effects, Interactions, Warnings & Dosing



GENOTROPIN is the brand name for somatropin and is available as a subcutaneous injection.

What dosages is GENOTROPIN available in?

What dosages is GENOTROPIN available in?

GENOTROPIN is available as one of the following:
GENOTROPIN lyophilized powder in a two-chamber color-coded cartridge:

  • 5 mg (green tip) and 12 mg (purple tip) (with preservative)
    GENOTROPIN MINIQUICK Growth Hormone Delivery Device containing a two-chamber cartridge (without preservative): 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 1.0 mg, 1.2 mg, 1.4 mg, 1.6 mg, 1.8 mg, and 2.0 mg
What is GENOTROPIN used for?

What is GENOTROPIN used for?

GENOTROPIN is a recombinant human growth hormone and is used for the following:

  • Certain growth-related conditions in children (e.g., low growth hormone, Turner Syndrome, Prader-Willi Syndrome)
  • Low growth hormone in adults
How does GENOTROPIN work?

How does GENOTROPIN work?

GENOTROPIN is a recombinant human growth hormone medication. It acts like our body’s natural growth hormone to promote growth in children. In adults, it helps control and maintain many important body functions, especially those that involve metabolism (how your body turns the food you eat into energy).

How do I take GENOTROPIN?

How do I take GENOTROPIN?

Somatropin injection is available as different brands:

  • Genotropin, Humatrope, Norditropin, Nutropin AQ, Omnitrope, Saizen, and Zomacton
  • Each brand contains a different amount of somatropin and has different administration instructions, so they are not interchangeable. Each brand also has specific dosing that’s based on the condition you’re being treated for. So, your provider will determine the right dose for you or your child
  • Growth-related conditions in children: The dose is based on your child’s body weight. The medication is injected under the skin either 3, 6, or 7 days a week. How often your child needs medication depends on the condition your child has and the brand medication that’s used. If needed, your provider might adjust the dose based on how your child responds to the medication
  • Low growth hormone in adults: There are two different ways the medication is dosed for adults. Some providers choose the dose based on your weight. Other providers might choose to start low and slowly raise the dose depending on how you respond to treatment. This medication is commonly injected under the skin once a day
Is it safe for me to take GENOTROPIN?

Is it safe for me to take GENOTROPIN?

GENOTROPIN is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

  • Acute Critical Illness
  • Children with Prader-Willi syndrome who are severely obese or have severe respiratory impairment – reports of sudden death
  • Active Malignancy
  • Hypersensitivity to somatropin or excipients
  • Active Proliferative or Severe Non-Proliferative Diabetic
  • Retinopathy
  • Children with closed epiphyses
GENOTROPIN Common Side Effects

GENOTROPIN Common Side Effects

Common side effects of GENOTROPIN:

  • Bruising
  • Headache
  • Leg pain
  • Swelling in the arms and legs
  • Joint pain
  • Upper respiratory infections
  • Pain in the arms and legs
GENOTROPIN Serious Side Effects

GENOTROPIN Serious Side Effects

Serious side effects are rare with GENOTROPIN. Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reactions: skin rash, hives, itching, swelling of face or tongue, trouble breathing, chest tightness
  • High blood pressure in the brain: changes in vision, headache, nausea, vomiting
  • Swelling of the pancreas (pancreatitis): nausea, vomiting, severe abdominal pain that spreads to your back
Effects of other drugs, drug classes and over-the-counter products on GENOTROPIN

Effects of other drugs, drug classes and over-the-counter products on GENOTROPIN

The following medications may interact with GENOTROPIN:

  • Inhibition of 11ß-Hydroxysteroid Dehydrogenase Type 1: May require the initiation of glucocorticoid replacement therapy. Patients treated with glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in their maintenance doses.
  • Glucocorticoid Replacement: Should be carefully adjusted
  • Cytochrome P450-Metabolized Drugs: Monitor carefully if used with somatropin
  • Oral Estrogen: Larger doses of somatropin may be required in women
  • Insulin and/or Oral/Injectable Hypoglycemic Agents: May require adjustment



Is GENOTROPIN safe in pregnancy?

Is GENOTROPIN safe in pregnancy?

It is not known if GENOTROPIN can harm your unborn baby. GENOTROPIN should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.


What to do if you missed your GENOTROPIN dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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