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Galsulfase is available as a 5 mg/5 mL (1 mg/mL) single-dose vial.

Galsulfase is used to improve the ability of people with Mucopolysaccharidosis VI to walk and climb stairs.

Galsulfase is a hydrolytic lysosomal glycosaminoglycan (GAG)-specific enzyme. People with Mucopolysaccharidosis VI either don’t have any or don’t have enough of an enzyme that breaks down a certain sugar called glycosaminoglycan (GAG). GAG builds up in your body over time and can cause symptoms, such as bone changes, vision changes, and heart problems. Galsulfase replaces the missing enzyme that breaks down the sugars, providing relief from some symptoms of this condition.

The recommended dosage of Galsulfase is 1 mg per kg of body weight administered once weekly as an intravenous infusion.

Galsulfase is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Galsulfase:

• Infusion-related reactions
• Stomach pain
• Joint pain
• Ear pain
• Pain
• Rash
• Pink eye
• Chills
• Trouble breathing

Serious side effects are rare with Galsulfase. Contact your healthcare provider immediately if you experience any of the following:

• Serious allergic reactions: swelling of the face, throat or tongue, wheezing, hives, rash, flushing, vomiting, trouble breathing

There are no major drug interactions listed for this medication. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Various FDA-approved generic manufacturers

It is not known whether this medication is safe for you and your unborn baby during pregnancy. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you.

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