Key facts about Etodolac
What dosages is Etodolac available in?
Etodolac is available as a 200 mg and 300 mg oral capsule and a 400 mg and 500 mg oral tablet.
What is Etodolac used for?
Etodolac is an NSAID that is used to treat acute (sudden onset) pain (immediate-release version only), osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis (extended-release version only).
How does Etodolac work?
Etodolac is a nonsteroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves pain and swelling.
How do I take Etodolac?
Etodolac is typically given as 200 mg to 400 mg by mouth every 6 to 8 hours. The maximum daily dose is 1 gram.
Is it safe for me to take Etodolac?
Etodolac is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to Etodolac, have experienced asthma, urticaria, or other allergic-type
reactions after taking aspirin or other NSAIDs, or for the treatment of peri-operative pain in the setting of coronary artery
bypass graft (CABG) surgery.
Etodolac Common Side Effects
Common side effects of Etodolac:
- Upset stomach or indigestion
- Stomach pain
- Diarrhea
- Gas
- Nausea
- Weakness
- Dizziness
Etodolac Serious Side Effects
Serious side effects are rare with Etodolac. Contact your healthcare provider immediately if you experience any of the following.
- Liver problems: nausea, fatigue, diarrhea, yellowing of skin or whites of the eyes
- Kidney problems: irregular heartbeat, shortness of breath, lower urine output, confusion, weakness
Heart attack: chest pain, sweating, shortness of breath, pain or discomfort in jaw, neck, or shoulders - Gastrointestinal (GI) bleeding: black or tarry stool, dizziness, stomach pain or discomfort
- Serious allergic reactions: hives, swelling of face, tongue, or throat, difficulty breathing
- Serious skin reactions: flu-like symptoms, painful rash or blisters all over body, peeling of skin
- Stroke: weakness on one side of the body, slurred speech, loss of balance, confusion
- Heart failure: shortness of breath, swelling or fluid buildup in ankles, feet, or legs, cough
Effects of other drugs, drug classes and over-the-counter products on Etodolac
The following medications may interact with Etodolac:
- ACE-Inhibitors and Angiotensin II Antagonists: Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors and angiotensin II antagonists. Etodolac can reduce the antihypertensive effects of captopril and losartan
- Aspirin: The use of Etodolac in conjunction with aspirin or other salicylates is not recommended
- Beta-adrenoceptor blocking agents: Blunting of the antihypertensive effect of beta-adrenoceptor blocking agents by non-steroidal antiinflammatory drugs including Etodolac has been reported
- Cyclosporine: Administration of non-steroidal anti-inflammatory drugs concomitantly with cyclosporine has been associated with an increase in cyclosporine-induced toxicity
- Digoxin: Etodolac given concomitantly with digoxin has been reported to increase the serum concentration and prolong the half-life of digoxin
- Probenecid: When Etodolac is given to patients receiving probenecid, the plasma levels of indomethacin are likely to be increased.
Who makes Etodolac?
Various FDA-approved generic manufacturers
Is Etodolac safe in pregnancy?
It’s not completely clear whether Etodolac is safe to take during the first 20 weeks of pregnancy. But you should avoid Etodolac after 20 weeks of pregnancy because it might cause developmental problems in your unborn baby or complications during delivery.
