DroxidopaPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Droxidopa
    Generic for Northera
    30 capsules $12 USD
    Save $471.90
  3. Droxidopa
    Generic for Northera
    45 capsules $15.9 USD
    Save $709.95
  4. Droxidopa
    Generic for Northera
    82 capsules $27 USD
    Save $1295.66
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Do you need a prescription for droxidopa?

Yes, droxidopa is only available with a valid physician Rx.

How much is droxidopa without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase droxidopa, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for droxidopa in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a droxidopa savings card?

Yes. Save up to 90% on your droxidopa with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a droxidopa coupon provider in the US?

No. Now Patient does not provide droxidopa coupons or FREE droxidopa samples.

Do you accept commercial, Medicare or Medicaid coverage for droxidopa in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much droxidopa?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using droxidopa. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much droxidopa. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

US brand name of droxidopa and manufacturer

Droxidopa is available in the US under the brand name Northera. It is manufactured by Lundbeck.

UK brand name of droxidopa and manufacturer

Droxidopa is not currently available in the UK.

Prescription requirement for droxidopa

Droxidopa is a prescription medication and requires a prescription from a healthcare provider.

FDA approval of droxidopa

Droxidopa has received FDA (Food and Drug Administration) approval for the treatment of neurogenic orthostatic hypotension, a condition characterized by a sudden drop in blood pressure upon standing (supine hypertension).

Active ingredient of droxidopa and mechanism of action

Droxidopa is in a class of medications called alpha and beta-adrenergic agonists. It works by increasing the levels of norepinephrine in the body. Norepinephrine is a neurotransmitter that helps to constrict blood vessels and increase blood pressure. By increasing norepinephrine levels, droxidopa helps to raise blood pressure and improve symptoms of NOH (symptomatic neurogenic orthostatic hypotension).

Uses of droxidopa

Droxidopa is primarily used for the treatment of symptomatic neurogenic orthostatic hypotension (symptomatic NOH) in patients with primary autonomic failure (Parkinson’s disease, multiple system atrophy, and pure autonomic failure), dopamine beta-hydroxylase deficiency, and non-diabetic autonomic neuropathy. It helps alleviate symptoms such as dizziness, lightheadedness, and fainting associated with NOH.

NOH is a type of low blood pressure that occurs when a person stands up or sits up from a lying position. It is typically caused by disorders of the autonomic nervous system, which is responsible for regulating bodily functions like heart rate and blood pressure.

Droxidopa is used by people whose daily activities are severely affected by this condition, even after other treatments are used. Treatment of symptomatic NOH is aimed at increasing standing systolic blood pressure into the range of approximately 50 to 150 mmHg.

Forms of droxidopa

Droxidopa is available in the form of oral capsules.

Dosage of droxidopa

The dosage of droxidopa will vary depending on the individual’s condition and the recommendation of their healthcare provider. It is important to follow the dosage instructions provided by your healthcare provider.

Precautions and warnings for droxidopa

  • Droxidopa should be used cautiously in individuals with certain medical conditions, such as heart failure, asthma, and renal impairment. It may worsen symptoms or interact with medications used to treat these conditions
  • Droxidopa may cause high blood pressure when lying down, especially at higher doses. Blood pressure should be monitored regularly
  • Droxidopa can increase the risk of certain cardiovascular events, such as heart attacks or arrhythmias. If you have severe heart disease, it is generally recommended to avoid taking droxidopa due to the potential risks involved
  • Droxidopa may interact with other medications, including certain blood pressure medications and medications that increase norepinephrine levels. Inform your healthcare provider about all the medicines you are taking
  • Droxidopa is not recommended for use during pregnancy unless the potential benefits outweigh the risks. It is not known if droxidopa passes into breast milk. There are no adequate clinical trials in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding

Side effects of droxidopa

Common side effects of droxidopa may include headache, dizziness, nausea, and high blood pressure. Other possible side effects include irregular heartbeat, chest pain, and allergic reactions. If you experience any severe or concerning side effects, seek medical attention.

Drug interactions

Droxidopa may interact with other medications, including carbidopa, ephedrine, medications for migraines, and midodrine. It is important to inform your healthcare provider about all the medicines you are taking to avoid adverse events.

Inform your doctor about all the medications, herbal supplements, or over-the-counter drugs you are taking to avoid any potential drug interactions.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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