chlorpromazine
Used for Schizophrenia and Anxiety
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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chlorpromazine Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is chlorpromazine available in?
chlorpromazine is available as a 30 mg/ml and 100 mg/ml oral concentrate and a 10 mg, 25 mg, 50 mg, 100 mg, and 200 mg oral tablet.
What is chlorpromazine used for?
chlorpromazine is a typical antipsychotic that is used for:
- Management of psychotic disorders
- Schizophrenia
- Nausea and vomiting
- Restlessness and anxiety before surgery
- Acute intermittent porphyria
- Tetanus
- Manic episodes of bipolar disorder
- Hiccups that won’t go away
- Severe behavioral issues in children 1 to 12 years old (e.g., aggressive behavior, frustration, explosive or hyperexcitable behavior)
How does chlorpromazine work?
chlorpromazine is an antipsychotic medication. It works by controlling dopamine activity in your brain, which affects your thoughts and mood. It also helps relax you and lowers nausea and vomiting.
How do I take chlorpromazine?
chlorpromazine dose varies depending on the condition you’re taking chlorpromazine for. In general, the typical dose ranges from 10 mg to 50 mg by mouth two to four times a day. If you’re taking chlorpromazine for restlessness and anxiety before surgery, the typical dose is 25 mg to 50 mg by mouth once, 2 to 3 hours before your procedure.
Is it safe for me to take chlorpromazine?
chlorpromazine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:
- Circulatory collapse.
- CNS depression, e.g. coma or drug intoxication.
Previous history of a hypersensitivity reaction (e.g. jaundice or blood dyscrasia) to phenothiazines, especially chlorpromazine itself, or to any of the excipients contained in the tablets or injection - Bone marrow depression
- Phaeochromocytoma
- Hepatic failure or active hepatic disease
chlorpromazine Common Side Effects
Common side effects of chlorpromazine:
- Drowsiness
- Uncontrollable muscle movements (e.g., neck spasms, difficulty swallowing and breathing, sticking your tongue out)
- Dry mouth
- Stuffy nose
- Nausea
- Constipation
- Bladder problems
chlorpromazine Serious Side Effects
Serious side effects are rare with chlorpromazine. Contact your healthcare provider immediately if you experience any of the following.
- Neuroleptic malignant syndrome: high fever, fast heart rate, full body stiffness, and confusion
- Very low blood pressure
- Seizures
Effects of other drugs, drug classes and over-the-counter products on chlorpromazine
The following medications may interact with chlorpromazine:
- Interactions resulting in decreased chlorpromazine levels
- Food, alcohol and benztropine can reduce the absorption of chlorpromazine. Antacids can slow the absorption of chlorpromazine. Lithium and chronic administration of barbiturates can lead to increased clearance of chlorpromazine
- Interactions resulting in increased chlorpromazine levels
- Tricyclic antidepressants decrease the clearance of chlorpromazine and may lead to increased serum levels.
- Administration of chlorpromazine with CYP1A2 inhibitors, in particular strong (such as ciprofloxacin and fluvoxamine) or moderate (such as oral contraceptives and vemurafenib) inhibitors leads to an increase in chlorpromazine plasma concentrations. Therefore, patients may experience any chlorpromazine dose-dependent adverse drug reaction
Who makes chlorpromazine?
Various FDA-approved generic manufacturers
Is chlorpromazine safe in pregnancy?
chlorpromazine should not be used in pregnant women, or those likely to become pregnant, unless the expected benefit outweighs any potential risk.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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