CALAN

CALAN is prescribed to manage hypertension, reducing blood pressure and lowering the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.

Potential side effects of this medication may include dizziness, slow heartbeat, constipation, nausea, headache, or tiredness. If any of these symptoms persist or worsen, promptly inform your doctor or pharmacist. To minimize the risk of dizziness and lightheadedness, rise slowly from a seated or lying position.

It may take up to a week for this drug to fully exhibit its high blood pressure treatment benefits. Continue taking this medication even if you feel well.

Verapamil’s vasodilator and negative inotropic effects in patients with normal or mildly impaired left ventricular function are balanced. However, severe left ventricular dysfunction may lead to abrupt decompensation, resulting in overt pulmonary edema and hypotension with verapamil treatment.

Verapamil produces fewer disruptive side effects compared to nifedipine and may offer a safe, non-addictive, and rational approach for long-term management of chronic dependence, withdrawal, and craving.

By blocking calcium entry into specific brain areas, verapamil induces relaxation in the brain and heart muscles, reducing certain brain activities. Consequently, it can alleviate symptoms of various heart conditions and potentially stabilize mood in bipolar disorder.

Calan, a calcium channel blocker, functions by relaxing the heart and blood vessel muscles. It is used to treat hypertension, angina, and specific heart rhythm disturbances.

Verapamil, a calcium channel blocker, affects calcium movement into heart and blood vessel cells. Consequently, it relaxes blood vessels, enhances blood and oxygen supply to the heart, and reduces cardiac workload.

This damage can affect the blood vessels of the brain, heart, and kidneys, leading to strokes, heart failure, or kidney failure.

Verapamil is used alone or in combination with other medications to treat heart rhythm disorders, severe chest pain (angina), or hypertension. Prolonged high blood pressure can impair the proper functioning of the heart and arteries.

While using verapamil, it is advisable to minimize grapefruit or grapefruit juice consumption. Consult your doctor before altering the quantity of these products in your diet if you have regularly consumed them with verapamil.

Although the evidence regarding calcium’s role in anxiety disorders is limited, drugs affecting calcium, such as verapamil, have been utilized to manage mood disorders.

Calan is used for the treatment of Arrhythmia, Angina, and High Blood Pressure. It falls under the drug classes of calcium channel blocking agents and group IV antiarrhythmics. Its safety during pregnancy cannot be guaranteed. Calan 80 mg is not a controlled substance under the Controlled Substances Act (CSA).

Taking this medication may result in low blood pressure (hypotension). Contact your doctor immediately if you experience symptoms such as blurred vision, confusion, severe dizziness, faintness upon abrupt position changes, sweating, or unusual tiredness or weakness.

Verapamil overdose may lead to heart failure due to reduced myocardial contractility and/or complete heart block. Hence, even seemingly low doses of verapamil can potentially cause heart failure, particularly in individuals with preexisting decreased contractility.

Verapamil should be avoided in individuals with HCM and those experiencing systemic hypotension or severe resting breathing difficulties.

Long-term use of verapamil can raise digoxin levels to a toxic extent. If you are taking digoxin in any form, your dosage may need adjustment, and close monitoring is essential.

Verapamil reduces blood vessel dilation, alleviating severe pain. It is currently the preferred drug for preventing episodic and chronic cluster headaches, with daily doses ranging from 360mg to occasionally 960mg.

Certain verapamil products should be taken in the morning, while others are best taken at bedtime. Follow your prescription label instructions carefully, and don’t hesitate to ask your doctor or pharmacist for clarification on any unclear aspects.

CALAN SR (verapamil hydrochloride) acts as a calcium ion influx inhibitor, also known as a slow-channel blocker or calcium ion antagonist.

Verapamil can be taken with or without food, but it’s essential to avoid grapefruit and grapefruit juice consumption while using this medication. Grapefruit can increase verapamil levels in the body, potentially intensifying side effects.

Available Dosage Forms:
– Trandolapril / verapamil: Oral tablet, extended release
– Lisinopril: Oral tablet
– Amlodipine: Oral tablet

Brand Names:
– Trandolapril / verapamil: N/A
– Lisinopril: Prinivil, Qbrelis, Zestril
– Amlodipine: Katerzia, Norliqva, Norvasc

Verapamil, a calcium channel blocker, widens blood vessels and relaxes heart muscles. This eases heart pumping, lowers blood pressure, and reduces heart rate.

Verapamil is prescribed to manage high blood pressure, which helps in preventing strokes, heart attacks, and kidney issues.

Mylan discontinued verapamil extended-release tablets in June 2021. Pfizer now offers Calan SR tablets.

Prolonged high blood pressure can impair the proper functioning of the heart and arteries, potentially leading to damage in the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.

The generic name is called verapamil (ver-AP-a-mil).

Verapamil, widely used as an antihypertensive agent and a calcium channel blocker, may have some degree of beta-blocking effects contributing to its pharmacological actions.

Possible side effects of verapamil include dizziness, slow heartbeat, constipation, nausea, headache, or fatigue. If any of these effects persist or worsen, consult your doctor or pharmacist. To reduce the risk of dizziness and lightheadedness, rise slowly when transitioning from a seated or lying position.

Taking your blood pressure medication before bedtime may promote a healthy nighttime dip in blood pressure, potentially offering protective effects to the heart.

Dihydropyridines primarily affect vascular smooth muscle, with nifedipine and amlodipine being the most potent, followed by the nondihydropyridines verapamil and diltiazem, which primarily act on the heart.

Verapamil is more effective in reducing blood pressure and rate-pressure responses to stress compared to amlodipine. Although plasma noradrenaline levels are lower with verapamil at rest and after stress, the increase during stress is not different.

Non-compliance with verapamil medication can lead to increased blood pressure, potentially requiring hospitalization and posing a risk of death. Overdosing may result in dangerously low blood pressure, bradycardia (slow heart rate), or gastrointestinal slowdown.

Excessive verapamil intake can lead to low blood pressure, dizziness, faintness, and irregular heart rhythms.

Prolonged high blood pressure can impair the proper functioning of the heart and arteries, potentially leading to damage in the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.

Verapamil can cause heart failure due to its potent negative inotropic effect and increased capillary filtration pressure resulting from vasodilation.

Liver injury from calcium channel blockers, although usually mild and reversible, can occasionally be symptomatic and severe. Verapamil, diltiazem, amlodipine, and nifedipine are most strongly associated with liver injury, likely due to their widespread use.

Contact your doctor if you experience shortness of breath, changes in heartbeat, dizziness, anxiety-like sensations, loss of appetite, yellowing of the skin or eyes, or flu-like symptoms while taking verapamil.

Possible skin-related side effects of verapamil include joint pain, rash, exanthema, hair loss, hyperkeratosis, maculae, sweating, urticaria, Stevens-Johnson syndrome, erythema multiforme. Special senses may be affected with blurred vision and tinnitus.