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Aptiom is the brand name for eslicarbazepine acetate oral tablets.

Aptiom is available as a 200 mg, 400 mg, 600 mg, or 800 mg oral tablet.

Aptiom is an antiepileptic and is used to treat partial-onset seizures.

Aptiom is an antiepileptic (anti-seizure) medication. It’s not entirely clear how this medication works, but it’s thought to target the activity of sodium channels in the brain. This might help calm down signaling from nerves and brain activity, which can help prevent seizures.

Aptiom is dosed as follows:

• Adults: The typical starting dose is 400 mg or 800 mg by mouth once daily. The dose is raised weekly based on how well you respond to the medication. The typical long-term (maintenance) dose is 800 mg to 1,600 mg once daily
• Children 4 to 17 years of age: The dose is based on your child’s weight and given by mouth once daily. The dose is raised weekly based on how well your child is responding to the medication. The starting dose ranges from 200 mg to 400 mg once daily, and the long-term (maintenance) dose ranges from 400 mg to 1,200 mg once daily

Your dose might differ if you have kidney problems or if you take certain other antiepileptics (e.g., carbamazepine (Tegretol), phenytoin (Dilantin), primidone (Mysoline)).

Aptiom is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a hypersensitivity to eslicarbazepine acetate or oxcarbazepine.

Common side effects of Aptiom:

• Dizziness
• Sleepiness
• Headache
• Nausea
• Double vision
• Vomiting
• Tiredness
• Blurry vision
• Difficulty with movement or coordination
• Feeling like the room is spinning
• Shakiness

Serious side effects are rare with Aptiom. Contact your healthcare provider immediately if you experience any of the following.

• Thoughts of hurting yourself or of suicide
• Low sodium levels: nausea, tiredness, headache, confusion, more seizures than usual
• Liver injury: severe nausea, vomiting, right-sided stomach pain, fatigue, low or no appetite, yellowing of the skin or eyes
• Allergic reaction: severe rash, hives, difficulty breathing, swelling of the face, mouth, or throat

The following medications may interact with Aptiom:

• Carbamazepine: May need dose adjustment for Aptiom or carbamazepine
• Phenytoin: Higher dosage of Aptiom may be necessary and dose adjustment may be needed for phenytoin.
• Phenobarbital or Primidone: Higher dosage of Aptiom may be necessary
• Hormonal Contraceptives: Aptiom may decrease the effectiveness of hormonal contraceptives

Sumitomo Pharma America, Inc.

Aptiom may harm your unborn baby. Tell your healthcare provider right away if you become pregnant while taking Aptiom. If you become pregnant while taking
Aptiom, talk to your healthcare provider about registering with the North American Antiepileptic Drug (NAAED) Pregnancy Registry. The purpose of this registry is to collect information about the safety of antiepileptic medicine during pregnancy. You can enroll in this registry by calling 1-888-233-2334.

• Eslicarbazepine Acetate