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Manufactured by various FDA-approved generic manufacturers.

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Navin Khosla NowPatientGreen tick
Updated on 24 Apr 2024

aprepitant Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is aprepitant available in?

What dosages is aprepitant available in?

aprepitant is available as a 80 mg and 125 mg oral capsule and 125 mg oral suspension.

What is aprepitant used for?

What is aprepitant used for?

aprepitant is an NK1 receptor antagonist and is used to prevent nausea and vomiting caused by certain chemotherapy. It is typically taken along with dexamethasone and a serotonin antagonist (e.g., ondansetron (Zofran).

How does aprepitant work?

How does aprepitant work?

aprepitant is an antiemetic that belongs to the drug class called NK1 receptor antagonists. It works by blocking certain chemicals in the brain that can cause nausea and vomiting. As a result, aprepitant helps ease both acute and delayed nausea and vomiting from chemotherapy.

How do I take aprepitant?

How do I take aprepitant?

aprepitant is typically dosed based on the chemotherapy regimen you’re getting and the other anti-nausea medications you’re taking. aprepitant is taken by mouth, typically 1 hour before your chemotherapy treatment.

Is it safe for me to take aprepitant?

Is it safe for me to take aprepitant?

aprepitant is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a known hypersensitivity to any component of this drug or are currently taking pimozide.

aprepitant Common Side Effects

aprepitant Common Side Effects

Common side effects of aprepitant include:

  • Tiredness
  • Diarrhea
  • Weakness
  • Indigestion
  • Belly pain
  • Hiccups
  • Lower white blood cell count
  • Headache
  • Low appetite
  • Cough
  • Dizziness
aprepitant Serious Side Effects

aprepitant Serious Side Effects

Serious side effects are rare with aprepitant.

Effects of other drugs, drug classes and over-the-counter products on aprepitant

Effects of other drugs, drug classes and over-the-counter products on aprepitant

The following medications may interact with aprepitant:

  • Multiple drug interactions because of extensive plasma protein binding, saturable metabolism and potent induction of hepatic enzymes such as aprepitant, alfuzosin, doxazosin, tamsulosin, amiodarone, cabazitaxel, docetaxel, doxorubicin, etoposide, ifosfamide, irinotecan and vincristine
Who makes aprepitant?

Who makes aprepitant?

Various FDA-approved generic manufacturers

Is aprepitant safe in pregnancy?

Is aprepitant safe in pregnancy?

It is not known if aprepitant will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.


What to do if you missed your aprepitant dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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