AllopurinolPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Allopurinol
    Generic for Zyloprim
    30 tablets $4.8 USD
    Save $6.60
  3. Allopurinol
    Generic for Zyloprim
    30 tablets $4.8 USD
    Save $6.60
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Do you need a prescription for allopurinol?

Yes, allopurinol is only available with a valid physician Rx.

How much is allopurinol without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase allopurinol, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for allopurinol in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a allopurinol savings card?

Yes. Save up to 90% on your allopurinol with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a allopurinol coupon provider in the US?

No. Now Patient does not provide allopurinol coupons or FREE allopurinol samples.

Do you accept commercial, Medicare or Medicaid coverage for allopurinol in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much allopurinol?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using allopurinol. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much allopurinol. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic allopurinol?

Generic allopurinol refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of allopurinol

Allopurinol is approved by the U.S. Food and Drug Administration (FDA) for the treatment of gout and certain types of kidney stones.

Active ingredient of allopurinol

The active ingredient of allopurinol is allopurinol.

US brand name of allopurinol and manufacturer

Allopurinol is available in the US under various brand names, including Zyloprim and Aloprim. It is manufactured by various pharmaceutical companies.

UK brand name of allopurinol and manufacturer

In the UK, allopurinol is available under various brand names, including Zyloric and Allural. The manufacturer may vary depending on the brand name.

Prescription requirement for allopurinol

A prescription (Rx) is required for allopurinol in both the US and the UK.

Availability of allopurinol in the UK with NHS prescription

Allopurinol is available in the UK with an NHS prescription.

Conditions treated by allopurinol

Allopurinol is primarily used for the treatment of gout, a type of arthritis caused by the buildup of uric acid levels in the joints. It may also be used to prevent certain types of kidney stones.

How does allopurinol work?

Allopurinol is in a class of medications called xanthine oxidase inhibitors. It works by inhibiting the production of uric acid in the body. It blocks the enzyme xanthine oxidase, which is involved in the production of uric acid. By reducing the levels of uric acid, allopurinol helps prevent gout attacks and the formation of certain types of kidney stones.

Forms of allopurinol available

Allopurinol is available in the form of oral tablets.

Dosage of allopurinol

The dosage of allopurinol may vary depending on the specific condition being treated and individual patient factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider.

Directions for allopurinol use

Allopurinol should be taken exactly as directed by the healthcare provider. Allopurinol tablets are usually taken once daily, preferably after meals, with a full glass of water. It is important to drink plenty of fluids while taking allopurinol to maintain proper hydration. If you miss a dose of allopurinol, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Warnings and precautions for allopurinol

  • Use allopurinol with caution in individuals with certain medical conditions, such as high blood pressure, liver disease or kidney problems. Dose adjustments may be necessary
  • It may interact with certain medications, including certain antibiotics like amoxicillin, ampicillin and blood thinners such as warfarin. Inform a healthcare professional about all prescription drugs, including over-the-counter medication and supplements being taken to prevent drug interactions
  • A very serious allergic reaction to this drug is rare. If you notice any symptoms of a serious allergic such as skin rash, itching, hives, or swelling of the face, lips, tongue, or throat or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling) get medical help right away

Drug interactions of allopurinol

Here are some examples of possible drug interactions with allopurinol:

  • Allopurinol can inhibit the breakdown of azathioprine and mercaptopurine leading to an increase in their levels in the body. This can potentially increase the risk of side effects or toxicity associated with azathioprine and mercaptopurine
  • Allopurinol may enhance the anticoagulant effects of warfarin, increasing the risk of bleeding. It is important to monitor blood clotting parameters closely if an individual is taking both medications concurrently
  • Allopurinol can reduce the effectiveness of certain water pills (diuretics) such as thiazides and loop diuretics. This can lead to an increased risk of gout attacks due to elevated uric acid levels
  • Allopurinol can inhibit the metabolism of theophylline, leading to an increase in blood levels. This can potentially result in toxicity and adverse effects associated with theophylline
  • Allopurinol can decrease the effectiveness of azathioprine and 6-mercaptopurine (commonly used to suppress the immune system in conditions like organ transplants). It is important to monitor the response to these medications and adjust the dose if necessary

Use of allopurinol during pregnancy

The use of allopurinol during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of allopurinol while breastfeeding

It is recommended to avoid the use of allopurinol while breastfeeding. It is important to discuss breastfeeding options with a healthcare provider.

Possible side effects of allopurinol

Common side effects of allopurinol may include rash, gastrointestinal upset, and drowsiness. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider.

Similar drugs to allopurinol

Other medications used for the treatment of gout and hyperuricemia include febuxostat and probenecid.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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