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allopurinol

allopurinol

Used for Gout

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Manufactured by various FDA-approved generic manufacturers.

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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Updated on 24 Apr 2024

allopurinol Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is allopurinol available in?

What dosages is allopurinol available in?

allopurinol is available as a 100 mg, 200 mg, and 300 mg oral tablet.

What is allopurinol used for?

What is allopurinol used for?

allopurinol is a xanthine oxidase inhibitor that is used to treat:

  • Gout
  • High uric acid in cancer
  • Recurrent kidney stones (kidney stones that keep coming back)
How does allopurinol work?

How does allopurinol work?

allopurinol stops an enzyme called xanthine oxidase from making uric acid; this then lowers the uric acid levels in your body. Keeping uric acid levels low can prevent gout attacks and kidney stones.

How do I take allopurinol?

How do I take allopurinol?

The daily dose of allopurinol will depend on your body’s levels of uric acid. The dose can be taken once a day or in divided doses throughout the day. The maximum daily dose is 800 mg. The typical starting dose for each indication is:

  • Gout: 100 mg daily
  • High uric acid in cancer: 600-800 mg daily for 2 or 3 days with lots of fluids
  • Recurrent kidney stones: 200-300 mg daily
Is it safe for me to take allopurinol?

Is it safe for me to take allopurinol?

allopurinol is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

allopurinol Common Side Effects

allopurinol Common Side Effects

Common side effects of allopurinol:

  • More gout attacks
  • Rash
  • Headache
  • Muscle and joint pain
  • Nerve pain
  • Change or loss in taste
  • Change in blood work
allopurinol Serious Side Effects

allopurinol Serious Side Effects

Serious side effects are rare with allopurinol.

Effects of other drugs, drug classes and over-the-counter products on allopurinol

Effects of other drugs, drug classes and over-the-counter products on allopurinol

The following medications may interact with allopurinol:

  • Several drug interactions exist with allopurinol. The most important drug interaction is with azathioprine and 6-mercaptopurine, both metabolized by the enzyme xanthine oxidase. Using any xanthine oxidase inhibitor such as allopurinol in a patient on azathioprine or 6-mercaptopurine can cause severe agranulocytosis and pancytopenia.
Who makes allopurinol?

Who makes allopurinol?

Various FDA-approved generic manufacturers

Is allopurinol safe in pregnancy?

Is allopurinol safe in pregnancy?

It is not known if allopurinol will harm your unborn baby. You and your doctor will have to decide if you should take allopurinol while you are pregnant or if you plan to become pregnant.

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What to do if you missed your allopurinol dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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