aflibercept
Are you tired of high medication costs? Our service offers unbeatable savings on your aflibercept prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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aflibercept key facts
What dosages is aflibercept available in?
aflibercept is available as a 2 mg (0.05 mL of 40 mg/mL) solution in a single-dose pre-filled syringe and single-dose vial.
What is aflibercept used for?
aflibercept is a VEGF inhibitor and is used for the following:
Wet age-related macular degeneration (wet AMD)
Macular edema following retinal vein occlusion (MEfRVO)
Diabetic retinopathy (DR)
Diabetic macular edema (DME)
Retinopathy of prematurity (ROP)
How does aflibercept work?
aflibercept is a vascular endothelial growth factor (VEGF) inhibitor. It blocks VEGF, a protein that makes new blood vessels in the body. When there’s too much of these proteins in the eye, it creates new, weak blood vessels which leak fluid into the back of the eye. By blocking VEGF proteins from working, aflibercept slows the growth of additional blood vessels to lessen the amount of fluid leaking in the eye. So it helps to lower the risk of vision loss in different eye conditions.
How do I take aflibercept?
aflibercept is dosed as follows:
The dose of aflibercept depends on the condition being treated. In general:
Adults
Wet AMD: The typical starting dose is 2 mg into the eye(s) once a month for 3 months. Afterwards, 2 mg once into the eye(s) every 2 months.
MEfRVO: The typical dose is 2 mg into the eye(s) once a month (about every 25 days).
DR and DME: The typical starting dose is 2 mg into the eye(s) once a month for the first 5 months. Afterwards, 2 mg once into the eye(s) every 2 months.
Children
ROP: The typical dose is one 0.4 mg injection into the eye(s). And if needed, your child might receive another injection 10 days after the first injection.
Is it safe for me to take aflibercept?
aflibercept is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following.
Ocular or periocular infection.
Active intraocular inflammation.
Hypersensitivity.
aflibercept Common Side Effects
- Common side effects of aflibercept:
- Cataract
- Eye pain
- Raised eye pressure
- Greater amount of eye floaters
- Blood spots on the whites of the eye
- Retinal detachment
aflibercept Serious Side Effects
Serious side effects are rare with aflibercept. Contact your healthcare provider immediately if you experience any of the following.
Eye infection (endophthalmitis): eye pain, sensitivity to light, loss of vision, eye redness
Separation of the retina from the back of the eye (retinal detachment): flashing lights, feeling like something is covering your vision, changes in your vision, or vision loss, seeing floaters
Effects of other drugs, drug classes and over-the-counter products on aflibercept
- There are no major drug interactions listed for aflibercept. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes aflibercept?
Various FDA-approved generic manufacturers
Is aflibercept safe in pregnancy?
It is not known if aflibercept will harm your unborn baby. Tell your healthcare provider if you become pregnant while taking aflibercept.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my aflibercept prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your aflibercept prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient aflibercept savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient aflibercept savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for aflibercept | Canadian Prescription Savings* for aflibercept | aflibercept Drug Coupon* | aflibercept Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of aflibercept?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for aflibercept | Canadian Prescription Savings* for aflibercept | aflibercept Drug Coupon* | aflibercept Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the aflibercept savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the aflibercept drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for aflibercept, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the aflibercept prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, aflibercept is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed aflibercept for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the aflibercept prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the aflibercept prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for aflibercept
If you are having trouble paying for your aflibercept medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for aflibercept you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- aflibercept is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers aflibercept
- If aflibercept is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for aflibercept
If you are having trouble paying for your aflibercept medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for aflibercept you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers aflibercept
- If aflibercept is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for aflibercept
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your aflibercept treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for aflibercept you will need to meet the following criteria:
- You must be currently insured and have coverage for aflibercept
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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NowPatient is owned and operated by Infohealth Ltd, a licensed online pharmacy with services spanning the UK, US and Rest of the World. Infohealth Ltd is registered in England and Wales under company number 04004930 and our registered office is at Lynwood House, 373 – 375 Station Road, Harrow, England, HA1 2AW.
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Our dispensing pharmacy is regulated and authorized for internet sales by the General Pharmaceutical Council (GPhC), registration number 1036487. You can view our license credentials on the General Pharmaceutical Council website. Our superintendent pharmacist who is responsible for the safe and effective oversight of medicines supplies is Mr Amish Patel (Registration Number 2042705).
Medicines are not ordinary items of commerce. All medicines or healthcare product sales are made under the supervision of a registered pharmacist who is licensed by the GPhC. At all times, we endeavour to provide a professional and transparent service whose primary goal is to ensure that the best interests of the patient are served.
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Our head of US services is Dr. Jamie Winn.
You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
We do not provide any prescribing services or dispensing services in the United States.
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