AcetaminophenPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Acetaminophen ER
    Generic for Tylenol
    30 extended release tablets $5.1 USD
    Save $1.50
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Do you need a prescription for acetaminophen?

Yes, acetaminophen is only available with a valid physician Rx.

How much is acetaminophen without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase acetaminophen, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for acetaminophen in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a acetaminophen savings card?

Yes. Save up to 90% on your acetaminophen with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a acetaminophen coupon provider in the US?

No. Now Patient does not provide acetaminophen coupons or FREE acetaminophen samples.

Do you accept commercial, Medicare or Medicaid coverage for acetaminophen in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much acetaminophen?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using acetaminophen. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much acetaminophen. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic acetaminophen?

Generic acetaminophen refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of acetaminophen

Acetaminophen is approved by the U.S. Food and Drug Administration (FDA) for the treatment of pain and fever.

Active Ingredient of Acetaminophen

The active ingredient of acetaminophen is acetaminophen.

US brand name of acetaminophen and manufacturer

Acetaminophen is available in the US under various brand names, including Tylenol, Excedrin, and Panadol. It is manufactured by different pharmaceutical companies.

UK brand name of acetaminophen and manufacturer

In the UK, acetaminophen is called paracetamol.

Prescription requirement for acetaminophen

Acetaminophen is available over the counter in both the US and the UK, and a prescription is not required for its purchase.

Availability of acetaminophen (paracetamol) in the UK with NHS prescription

Acetaminophen is widely available in the UK without a prescription or with a prescription through the NHS.

Conditions treated by acetaminophen

Acetaminophen is primarily used for mild to moderate pain relief and reduction of fever associated with various conditions, including headache, muscle aches, toothache, backache, osteoarthritis and cold or flu symptoms. It can be used alone or in combination with opioids such as codeine and hydrocodone for severe pain management.

How does acetaminophen work?

The exact mechanism of action of acetaminophen is not fully understood. It is believed to work by inhibiting the production of certain substances in the body that are involved in pain and fever. Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers).

Forms of acetaminophen available

Acetaminophen comes in many different forms such as capsules, liquid, chewable tablets or disintegrating tablets, and dissolving powders or granules.

Dosage of acetaminophen

The dosage of acetaminophen may vary depending on the individual’s age, weight, and the specific condition being treated. It is important to follow the recommended dosage instructions provided on the product packaging or as directed by a healthcare provider.

Directions for acetaminophen use

Acetaminophen should be used exactly as directed by the product label or as advised by a healthcare provider. The medication is usually taken orally with or without food. It is important to follow the recommended dosing intervals and avoid exceeding the maximum daily dose.

Warnings and precautions for acetaminophen

  • High doses of acetaminophen (acetaminophen overdose) can cause liver damage if taken in excessive amounts or combined with certain medications or alcohol. It is important to follow the recommended dosage and avoid exceeding the maximum daily dose
  • It may interact with other medications, including those that also contain acetaminophen. It is important to read the labels of all medications to avoid accidental overdose. Tell your doctor and pharmacist what prescription and nonprescription medications, OTC (over-the-counter) medications vitamins, nutritional supplements, or herbal products you are taking or plan to take

Drug interactions

  • It is crucial to avoid taking multiple medications containing acetaminophen simultaneously. Doing so can lead to an unintentional overdose, which can cause liver damage and other serious health complications. Always read the labels of all over-the-counter and prescription medications to check for acetaminophen content
  • NSAIDs (nonsteroidal anti-inflammatory drugs) like ibuprofen, aspirin, and naproxen should be used with caution while taking acetaminophen. These medications also have analgesic and antipyretic properties, and combining them with acetaminophen may increase the risk of side effects, particularly related to the stomach and kidneys. If both drugs are necessary, consult a healthcare professional to determine appropriate dosages and schedules
  • Consuming alcohol while taking acetaminophen can increase the risk of liver damage. Both acetaminophen and alcohol are metabolized by the liver, and the combination can put extra stress on this vital organ. It is advisable to avoid alcohol while using acetaminophen or to limit alcohol consumption to moderate levels to minimize the risk of liver damage
  • If you have a chronic condition such as liver disease, kidney disease, or gastrointestinal ulcers, it is important to consult your healthcare professional before using acetaminophen. These conditions may affect how your body processes the medication and increase the risk of side effects or complications. Your healthcare professional can provide guidance on the appropriate use and dosage of acetaminophen based on your specific condition

Use of acetaminophen during pregnancy

Acetaminophen is generally considered safe to use during pregnancy when taken at recommended doses. However, it is recommended to consult a healthcare provider for medical advice before using any medication during pregnancy.

Use of acetaminophen while breastfeeding

Acetaminophen is considered safe to use while breastfeeding when taken at recommended doses. It is important to follow the recommended dosage instructions and consult a healthcare provider if any concerns arise.

Possible side effects of acetaminophen

When used as directed, acetaminophen is generally well-tolerated. However, common side effects may include nausea, stomach pain, and allergic reactions. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare professional.

Similar drugs to acetaminophen

Other over-the-counter pain relievers and fever reducers include ibuprofen, aspirin, and naproxen. These medications may have different mechanisms of action and considerations for use.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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