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Semaglutide is available as a 2 mg/3 ml, 4 mg/3 ml, and 8 mg/3 ml subcutaneous injection.

Semaglutide is a GLP-1 agonist and is used for the following:

• Type 2 diabetes
• Lower the risk of heart attack, stroke, and heart-related death in adults with type 2 diabetes and heart disease

Semaglutide is a glucagon-like peptide-1 (GLP-1) agonist, meaning it acts like the natural GLP-1 hormone in the body. This hormone works to lower your blood sugar by causing your pancreas to release more insulin, stopping your liver from releasing more sugar, and slowing down your digestion.

• Semaglutide is typically started at 0.25 mg injected under the skin once per week for 4 weeks. After 4 weeks, your provider will raise your dose to 0.5 mg injected under the skin once per week
• If needed, your provider might raise your dose even further to 1 mg or 2 mg once per week, after being on a lower dose for at least 4 weeks. The maximum total dose is 2 mg per week

Semaglutide is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:

• Personal or family history of thyroid cancer
• Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Common side effects of Semaglutide:

• Nausea
• Diarrhea
• Vomiting
• Stomach pain
• Constipation

Serious side effects are rare with Semaglutide. Contact your healthcare provider immediately if you experience any of the following.

• Thyroid cancer: mass in the neck, trouble breathing or swallowing, hoarseness
• Inflammation of the pancreas (pancreatitis): stomach or back pain that won’t go away, vomiting
  Low blood sugar: shaking, sweating, dizziness, confusion, blurred vision
• Kidney problems: changes in urination, blood in your urine, swollen feet or ankles, smaller appetite, muscle cramping
• Gallbladder problems: pain in the upper stomach, fever, yellowing of the whites of the eyes, clay-colored stool
• Serious allergic reactions: trouble breathing, hives, itching, swelling of your face, lips, tongue, or throat

The following medications may interact with Semaglutide:

• Oral Medications: Semaglutide delays gastric emptying. May impact absorption of concomitantly administered oral medications. Use with caution

Various FDA-approved generic manufacturers

Discontinue Semaglutide in women at least 2 months
before a planned pregnancy due to the long washout period for Semaglutide.

• Ozempic
• Rybelsus
• Wegovy Injection
• Wegovy Pills