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MEDICAL INFORMATION
Wegovy Pills Key Facts
What is Wegovy Pills?
Wegovy Pills (semaglutide) is the first and only FDA-approved GLP-1 pill for weight loss, developed by Novo Nordisk. It’s a prescription medicine containing semaglutide that is taken once daily, as opposed to the injectable, once-weekly, version of Wegovy.
What dosages is Wegovy Pills available in?
The Wegovy pill uses a gradual dose escalation schedule. Your health care professional will start you on the 1.5 mg once-daily dose and gradually increase the dose every 30 days until you reach the 25 mg maximum dose. The dosing schedule includes: 1.5 mg, 4 mg, 9 mg, and 25 mg strengths.
What is Wegovy Pills used for?
Wegovy Pills are used for:
- Weight Loss & Long‑Term Weight Management
Wegovy Pills help adults with obesity or who are overweight (with at least one weight‑related medical problem such as high blood pressure, type 2 diabetes, or high cholesterol) to lose weight and maintain that weight loss. - Cardiovascular Risk Reduction
In adults who have established cardiovascular disease and obesity or overweight, Wegovy can be prescribed to reduce the risk of major cardiovascular events (like heart attack, stroke, or death) when used alongside diet and exercise.
How does Wegovy Pills work?
Wegovy Pills contain semaglutide, a GLP-1 receptor agonist. The FDA-approved Wegovy® pill has technology designed to facilitate absorption of semaglutide.
The medication works as part of a GLP-1 class mechanism to help with weight management.
In clinical trials, adults lost on average 33 lb (14% weight loss) based on an average starting weight of 235 lb with Wegovy Pills, compared to 6 lb (2.4% weight loss) with placebo.
How do I take Wegovy Pills?
Wake up and take one WEGOVY PILL with a sip of water (up to 4 ounces) on an empty stomach. Start your morning while waiting at least 30 minutes before eating or drinking or taking other oral medications.
Key instructions include:
- Take one pill by mouth with water (4 oz max) and not with other liquids. Don’t crush, cut, chew, or dissolve the pill
- Wait at least 30 minutes before eating, drinking, or taking other oral medications to give Wegovy® pill time to absorb
- Store pills in the closed Wegovy® bottle until you are ready to take one, not in another container
- Do not take more than 1 pill per day
- If you miss a dose, the missed dose should be skipped, and the next dose should be taken the following day
Is it safe for me to take Wegovy Pills?
Do not use Wegovy Pills if:
- You or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- You have had a serious allergic reaction to semaglutide or any of the ingredients in WEGOVY INJECTION or Wegovy Pills
Tell your healthcare provider if you:
- Have or have had problems with your pancreas or kidneys
- Have type 2 diabetes and a history of diabetic retinopathy
- Have or have had depression, suicidal thoughts, or mental health issues
- Are scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)
Wegovy Pills contain semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.
Wegovy Pills Common Side Effects
- nausea
- diarrhea
- vomiting
- constipation
- stomach (abdomen) pain
- headache
- tiredness (fatigue)
- upset stomach
- dizziness
- feeling bloated
- belching
- low blood sugar in people with type 2 diabetes
- gas
- stomach flu
- heartburn
- runny nose
- sore throat
Wegovy Pills Serious Side Effects
- Thyroid tumors: In studies with rodents, Wegovy Pills and other medicines that work like Wegovy® caused thyroid tumors, including thyroid cancer. It is not known if Wegovy Pills will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.
- Pancreatitis: Stop using Wegovy Pills and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without nausea or vomiting.
- Gallbladder problems: Wegovy Pills may cause gallbladder problems, including gallstones. Some gallstones may need surgery.
- Low blood sugar (hypoglycemia): Increased risk of low blood sugar, especially those who also take medicines for diabetes such as insulin or sulfonylureas.
- Kidney problems: Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems.
- Severe stomach problems: Stomach problems, sometimes severe, have been reported in people who use Wegovy Pills
- Serious allergic reactions: Stop using Wegovy Pills and get medical help right away, if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching.
- Vision changes: Change in vision in people with type 2 diabetes.
- Increased heart rate: Wegovy Pills can increase your heart rate while you are at rest.
- Mental health effects: Depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes in your mood, behaviors, thoughts, or feelings.
- Aspiration risk: Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation).
Effects of other drugs, drug classes and over-the-counter products on Wegovy Pills
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Wegovy Pills may affect the way some medicines work and some medicines may affect the way Wegovy Pills works.
Tell your healthcare provider if you are taking other medicines to treat diabetes, including sulfonylureas or insulin. Wegovy Pills slows stomach emptying and can affect medicines that need to pass through the stomach quickly.
Who makes Wegovy Pills?
Novo Nordisk Inc.
Is Wegovy Pills safe in pregnancy?
No. Wegovy Pills may harm your unborn baby. You should stop using Wegovy Pills, 2 months before you plan to become pregnant.
Regarding breastfeeding: Breastfeeding is not recommended during treatment with Wegovy Pills.
What is the generic name for Wegovy Pills?
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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