paliperidone palmitate

paliperidone palmitate

Used for Schizophrenia

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Manufactured by various FDA-approved generic manufacturers.

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paliperidone palmitate Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is paliperidone palmitate available in?

What dosages is paliperidone palmitate available in?

paliperidone palmitate is available as a 273 mg/0.88 mL, 410 mg/1.32 mL, 546 mg/1.75 mL, or 819 mg/2.63 mL extended-release injectable suspension.

What is paliperidone palmitate used for?

What is paliperidone palmitate used for?

  • paliperidone palmitate is an atypical antipsychotic and is used to treat schizophrenia
How does paliperidone palmitate work?

How does paliperidone palmitate work?

paliperidone palmitate is an atypical antipsychotic. It can affect dopamine and serotonin levels in your brain, which helps control your thoughts, mood, and behaviors.

How do I take paliperidone palmitate?

How do I take paliperidone palmitate?

  • paliperidone palmitate is given as an injection into the muscle by a healthcare provider. It should only be used after you’ve taken Invega Sustenna (paliperidone) for at least 4 months. Your provider will determine your dose based on what dose of Invega Sustenna (paliperidone) you were taking
  • You’ll receive your first dose of paliperidone palmitate when your next 1-month Invega Sustenna (paliperidone) dose is due. After that, paliperidone palmitate is injected once every 3 months. The typical dose ranges from 273 mg to 819 mg
Is it safe for me to take paliperidone palmitate?

Is it safe for me to take paliperidone palmitate?

paliperidone palmitate is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have an allergy to paliperidone (Invega) or risperidone (Risperdal).

paliperidone palmitate Common Side Effects

paliperidone palmitate Common Side Effects

Common side effects of paliperidone palmitate:

  • Upper respiratory tract infection
  • Weight gain
  • Headache
  • Not able to stay still
paliperidone palmitate Serious Side Effects

paliperidone palmitate Serious Side Effects

Serious side effects are rare with paliperidone palmitate.Contact your healthcare provider immediately if you experience any of the following.

  • Seizures
  • Difficulty swallowing
  • Neuroleptic malignant syndrome: high fever, muscle stiffness, confusion, sweating, changes in pulse, heart rate, changes in blood pressure
  • Tardive dyskinesia: uncontrolled muscle movements, such as facial grimacing, lip-smacking, blinking
  • Extremely high blood sugar levels: feeling very hungry or thirsty, urinating more often, stomach pain, weakness, fruity-smelling breath
  • Serious infections: fever, chills, body aches, tiredness, cough
  • Priapism: painful erection that that lasts longer than 4 hours
Effects of other drugs, drug classes and over-the-counter products on paliperidone palmitate

Effects of other drugs, drug classes and over-the-counter products on paliperidone palmitate

The following medications may interact with paliperidone palmitate:

  • Strong CYP3A4/P-glycoprotein (P-gp) inducers: Avoid using a strong inducer of CYP3A4 and/or P-gp (e.g., carbamazepine, rifampin, St John’s Wort) during a dosing interval for paliperidone palmitate. If administering a strong inducer is necessary, consider managing the patient using paliperidone extended release tablets
Who makes paliperidone palmitate?

Who makes paliperidone palmitate?

Various FDA-approved generic manufacturers

Is paliperidone palmitate safe in pregnancy?

Is paliperidone palmitate safe in pregnancy?

paliperidone palmitate may cause extrapyramidal and/or withdrawal symptoms in neonates with third trimester exposure. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to atypical antipsychotics, including paliperidone palmitate, during pregnancy. Healthcare providers are encouraged to register patients by contacting the National Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or online at women’s health


What to do if you missed your paliperidone palmitate dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

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NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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