INVEGA TRINZA
Used for Schizophrenia
NowPatient helps you obtain your INVEGA TRINZA prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Janssen Pharmaceuticals
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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INVEGA TRINZA key facts
What is INVEGA TRINZA?
INVEGA TRINZA is the brand name for paliperidone palmitate and is available as an extended-release injectable suspension.
What dosages is INVEGA TRINZA available in?
INVEGA TRINZA is available as a 273 mg/0.88 mL, 410 mg/1.32 mL, 546 mg/1.75 mL, or 819 mg/2.63 mL extended-release injectable suspension.
What is INVEGA TRINZA used for?
- INVEGA TRINZA is an atypical antipsychotic and is used to treat schizophrenia
How does INVEGA TRINZA work?
INVEGA TRINZA is an atypical antipsychotic. It can affect dopamine and serotonin levels in your brain, which helps control your thoughts, mood, and behaviors.
How do I take INVEGA TRINZA?
- INVEGA TRINZA is given as an injection into the muscle by a healthcare provider. It should only be used after you’ve taken Invega Sustenna (paliperidone) for at least 4 months. Your provider will determine your dose based on what dose of Invega Sustenna (paliperidone) you were taking
- You’ll receive your first dose of INVEGA TRINZA when your next 1-month Invega Sustenna (paliperidone) dose is due. After that, INVEGA TRINZA is injected once every 3 months. The typical dose ranges from 273 mg to 819 mg
Is it safe for me to take INVEGA TRINZA?
INVEGA TRINZA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have an allergy to paliperidone (Invega) or risperidone (Risperdal).
INVEGA TRINZA Common Side Effects
Common side effects of INVEGA TRINZA:
- Upper respiratory tract infection
- Weight gain
- Headache
- Not able to stay still
INVEGA TRINZA Serious Side Effects
Serious side effects are rare with INVEGA TRINZA.Contact your healthcare provider immediately if you experience any of the following.
- Seizures
- Difficulty swallowing
- Neuroleptic malignant syndrome: high fever, muscle stiffness, confusion, sweating, changes in pulse, heart rate, changes in blood pressure
- Tardive dyskinesia: uncontrolled muscle movements, such as facial grimacing, lip-smacking, blinking
- Extremely high blood sugar levels: feeling very hungry or thirsty, urinating more often, stomach pain, weakness, fruity-smelling breath
- Serious infections: fever, chills, body aches, tiredness, cough
- Priapism: painful erection that that lasts longer than 4 hours
Effects of other drugs, drug classes and over-the-counter products on INVEGA TRINZA
The following medications may interact with INVEGA TRINZA:
- Strong CYP3A4/P-glycoprotein (P-gp) inducers: Avoid using a strong inducer of CYP3A4 and/or P-gp (e.g., carbamazepine, rifampin, St John’s Wort) during a dosing interval for INVEGA TRINZA. If administering a strong inducer is necessary, consider managing the patient using paliperidone extended release tablets
Who makes INVEGA TRINZA?
Janssen Pharmaceuticals
Is INVEGA TRINZA safe in pregnancy?
INVEGA TRINZA may cause extrapyramidal and/or withdrawal symptoms in neonates with third trimester exposure. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to atypical antipsychotics, including INVEGA TRINZA, during pregnancy. Healthcare providers are encouraged to register patients by contacting the National Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or online at women’s health
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my INVEGA TRINZA prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your INVEGA TRINZA prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient INVEGA TRINZA savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient INVEGA TRINZA savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for INVEGA TRINZA | Canadian Prescription Savings* for INVEGA TRINZA | INVEGA TRINZA Drug Coupon* | INVEGA TRINZA Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of INVEGA TRINZA?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for INVEGA TRINZA | Canadian Prescription Savings* for INVEGA TRINZA | INVEGA TRINZA Drug Coupon* | INVEGA TRINZA Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the INVEGA TRINZA savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the INVEGA TRINZA drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for INVEGA TRINZA, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the INVEGA TRINZA prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, INVEGA TRINZA is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed INVEGA TRINZA for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the INVEGA TRINZA prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the INVEGA TRINZA prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for INVEGA TRINZA
If you are having trouble paying for your INVEGA TRINZA medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for INVEGA TRINZA you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- INVEGA TRINZA is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers INVEGA TRINZA
- If INVEGA TRINZA is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for INVEGA TRINZA
If you are having trouble paying for your INVEGA TRINZA medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for INVEGA TRINZA you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers INVEGA TRINZA
- If INVEGA TRINZA is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for INVEGA TRINZA
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your INVEGA TRINZA treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for INVEGA TRINZA you will need to meet the following criteria:
- You must be currently insured and have coverage for INVEGA TRINZA
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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