Used for Depression

View vortioxetine savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or vortioxetine Patient Assistance Program.

Programs are suitable for individuals who want to buy vortioxetine without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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Updated on 24 Apr 2024

Learn more about vortioxetine

What dosages is vortioxetine available in?

What dosages is vortioxetine available in?

vortioxetine is available as 5 mg, 10 mg, and 20 mg oral tablet.

What is vortioxetine used for?

What is vortioxetine used for?

vortioxetine is an atypical antidepressant and is used to treat depression.

How does vortioxetine work?

How does vortioxetine work?

vortioxetine is an atypical antidepressant. Although it’s not fully understood, it seems to work by boosting the action of serotonin in your brain. Serotonin is a neurotransmitter (communication molecule) that’s associated with well-being and happiness.

How do I take vortioxetine?

How do I take vortioxetine?

vortioxetine is typically started at 10 mg by mouth once daily. The maximum dose is 20 mg by mouth per day.

  • Your dose will depend on what other medications you’re taking and how you respond to vortioxetine
Is it safe for me to take vortioxetine?

Is it safe for me to take vortioxetine?

vortioxetine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because vortioxetine will not be safe for you to take. Taking a monoamine oxidase inhibitor (MAOI) within 21 days of vortioxetine.

vortioxetine Common Side Effects

vortioxetine Common Side Effects

Common side effects of vortioxetine:

  • Nausea
  • Diarrhea
  • Dizziness
  • Dry mouth
  • Vomiting
  • Constipation
vortioxetine Serious Side Effects

vortioxetine Serious Side Effects

Serious side effects are rare with vortioxetine. Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts and behavior
  • Serotonin syndrome: fast heart rate, sweating, muscle stiffness or spasms, fever, confusion
  • Very low levels of sodium (hyponatremia): nausea, vomiting, headache, memory problems, confusion, muscle weakness or cramps, low blood pressure
  • Serious bleeding: dizziness, pale skin, feeling weak, bleeding that’s difficult to stop, bruising that won’t go away, vomiting blood, black and tarry stool
Effects of other drugs, drug classes and over-the-counter products on vortioxetine

Effects of other drugs, drug classes and over-the-counter products on vortioxetine

The following medications may interact with vortioxetine:

  • Strong inhibitors of CYP2D6: Reduce vortioxetine dose by half when a strong CYP2D6 inhibitor (e.g., bupropion, fluoxetine paroxetine, or quinidine) is coadministered
  • Strong CYP Inducers: Consider increasing vortioxetine dose when a strong CYP inducer (e.g., rifampin, carbamazepine, or phenytoin) is coadministered for more than 14 days. The maximum recommended dose should not exceed 3 times the original dose
Who makes vortioxetine?

Who makes vortioxetine?

Various FDA-approved generic manufacturers

Is vortioxetine safe in pregnancy?

Is vortioxetine safe in pregnancy?

It is not known if vortioxetine will harm your unborn baby. Taking vortioxetine while pregnant in your third trimester may cause your newborn baby to have withdrawal symptoms that causes a certain type of breathing problem called Persistent Pulmonary Hypertension of the Newborn (PPHN).


What to do if you missed your vortioxetine dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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