Key facts about Brintellix
What is Brintellix?
Trintellix is the brand name for vortioxetine and is available as an oral tablet.
What dosages is Brintellix available in?
Trintellix is available as 5 mg, 10 mg, and 20 mg oral tablet.
What is Brintellix used for?
Trintellix is an atypical antidepressant used for the treatment of major depressive disorder (MDD) in adults.
How does Brintellix work?
Trintellix is an atypical antidepressant. It’s not fully understood how the medication works. But researchers think it helps boost serotonin in your brain. Serotonin is a chemical in the brain that plays a role in regulating mood and emotion.
How do I take Brintellix?
The recommended starting dose is 10 mg by mouth once daily without regard to meals. The dose should then be increased to 20 mg/day, as tolerated. Consider 5 mg/day for patients who do not tolerate higher doses.
Is it safe for me to take Brintellix?
Trintellix is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Take a monoamine oxidase inhibitor (MAOI) within 21 days of Trintellix
- Hypersensitivity to vortioxetine or any components of the product
Brintellix Common Side Effects
Common side effects of Trintellix:
- Nausea
- Diarrhea
- Dizziness
- Dry mouth
- Vomiting
- Constipation
Brintellix Serious Side Effects
Serious side effects are rare with Trintellix. Contact your healthcare provider immediately if you experience any of the following:
- Suicidal thoughts and behavior
- Serotonin syndrome: fast heart rate, sweating, muscle stiffness or spasms, fever, confusion
- Very low sodium: nausea, vomiting, headache, memory problems, confusion, muscle weakness or cramps, low blood pressure
- Serious bleeding: dizziness, pale skin, feeling weak, getting nosebleeds often, bleeding that’s hard to stop, bruising that won’t go away, vomiting blood, black and tarry stool
Effects of other drugs, drug classes and over-the-counter products on Brintellix
The following medications may interact with Trintellix:
- Strong inhibitors of CYP2D6
- Strong CYP inducers
Who makes Brintellix?
Lundbeck
Is Brintellix safe in pregnancy?
Trintellix may harm your unborn baby. Taking it during your third trimester of pregnancy may cause your baby to have withdrawal symptoms after birth or may cause your baby to be at increased risk for a serious lung problem at birth. Talk to your healthcare provider about the risks to you and your unborn or newborn baby if you take Trintellix during pregnancy. Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment
